カテゴリー「no classified」
Author: L. Litcher, E.J. Bromet, G. Carlson et al.
Reference: J. Child. Psychol. Psychiatry. — 2000. — Vol. 3, № 41. — P. 291–299.
Keywords: neuropsychological functioning, Pripyat, Benton Form A, mothers, Conners Teacher’s Rating Scale
Abstract: This paper examines the cognitive and neuropsychological functioning of children who were in utero to age 15 months at the time of the Chornobyl disaster and were evacuated to Kyiv from the 30-kilometer zone surrounding the plant. Specifically, we compared 300 evacuee children at ages 10–12 with 300 non-evacuee Kyiv classmates on objective and subjective measures of attention, memory, and school performance. The evacuee children were not significantly different from their classmates on the objective measures (grades; Symbolic Relations subtest of the Detroit Test; forms 1 and 2 of the Visual Search and Attention Test; Benton Form A; Trails A; Underline the Words Test) or on most of the subjective measures (the attention subscale of the Child Behavior Checklist completed by mothers; the attention items of the Iowa Conners Teacher’s Rating Scale; mother and child perceptions of school performance). The one exception was that 31.3% of evacuee mothers compared to 7.4% of classmate mothers indicated that their child had a memory problem. However, this subjective measure of memory problems was not significantly related to neuropsychological or school performance. No significant differences were found in comparisons of evacuees and classmates who were in utero at the time of the explosion, children from Pripyat vs. other villages in the 30-kilometer zone, and children manifesting greater generalized anxiety. For both groups, children with greater Chornobyl-focused anxiety performed significantly worse than children with less Chornobyl-focused anxiety on measures of attention. The results thus fail to confirm two previous reports that relatively more children from areas contaminated by radiation had cognitive deficits compared to controls. Possible reasons for the differences in findings among the studies are discussed. (full text available on web)
URL: http://www.upa-psychiatry.org.ua/articles/LitcherNeuropsych.pdf
Author: Sadetzki S, Chetrit A, Mandelzweig L, Nahon D, Freedman L, Susser E, Gross R.
Reference: Radiat Res. 2011, 176 (5): 670–677.
Keywords: schizophrenia
Abstract: The aim of our study was to assess risk of schizophrenia after childhood exposure to ionizing radiation to the head (mean dose: 1.5 Gy).
No statistically significant association was found between radiation exposure and schizophrenia for the total group (hazard ratio per 1 Gy to the brain: 1.05, 95% confidence interval: 0.93-1.18) or within subgroups of sex, dose categories or latent period. When comparing a subgroup of subjects irradiated under 5 years of age with the matched unexposed group, the estimated hazard ratio reached 1.18 (95% confidence interval: 0.96-1.44; P = 0.1). The results of our analysis do not support an association between exposure to ionizing radiation and risk of schizophrenia. Further research is required.
URL: http://www.ncbi.nlm.nih.gov/pubmed/22026716
Author: J. Raber, R. Rola, A. LeFevour et al.
Reference: Radiat. Res. ― 2004. ― Vol. 162, № 1. ― P. 39–47.
Keywords: brain tumor, arteriovenous malformation, cognitive function, learning memory
Abstract: During treatment of brain tumors, some head and neck tumors, and other diseases, like arteriovenous malformations, the normal brain is exposed to ionizing radiation. While high radiation doses can cause severe tissue destruction, lower doses can induce cognitive impairments without signs of overt tissue damage. The underlying pathogenesis of these impairments is not well understood but may involve the neural precursor cells in the dentate gyrus of the hippocampus. To assess the effects of radiation on cognitive function, 2-month-old mice received either sham treatment (controls) or localized X irradiation (10 Gy) to the hippocampus/cortex and were tested behaviorally 3 months later. Compared to controls, X-irradiated mice showed hippocampal-dependent spatial learning and memory impairments in the Barnes maze but not the Morris water maze. No nonspatial learning and memory impairments were detected. The cognitive impairments were associated with reductions in proliferating Ki-67-positive cells and Doublecortin-positive immature neurons in the subgranular zone (SGZ) of the dentate gyrus. This study shows significant cognitive impairments after a modest dose of radiation and demonstrates that the Barnes maze is particularly sensitive for the detection of radiation-induced cognitive deficits in young adult mice. The significant loss of proliferating SGZ cells and their progeny suggests a contributory role of reduced neurogenesis in the pathogenesis of radiation-induced cognitive impairments.
URL: http://www.ncbi.nlm.nih.gov/pubmed/15222778
Author: V.K. Ivanov, M.A. Maksioutov, S.Yu. Chekin et al.
Reference: Health Physics. — 2000. — Vol. 78, № 5. — P. 495–501.
Keywords: liquidator, Russian National Medical and Dosimetric Registry, cerebrovascular disease
Abstract: The work is concerned with assessment of radiation risks for non-cancer disease among the Chernobyl liquidators from 1986 to 1996. As of 1 January 1999, the Russian National Medical and Dosimetric Registry contains medical and dosimetric data for 174,000 liquidators. The cohort of 68,309 liquidators for whom best verified medical data are available is discussed. The dose dependency of incidence of non-cancer diseases was estimated by the cohort method and using the software package Epicure. For some classes of non-cancer diseases among liquidators, statistically significant estimates of radiation risk were derived for the first time. The highest excess relative risk per 1 Gy was found for cerebrovascular diseases; ERR Gy(-1)=1.17 at the 95% confidence interval (0.45; 1.88).
URL: http://www.ncbi.nlm.nih.gov/pubmed/10772021
Author: Y. Shimizu, K. Kodama, N. Nishi et al.
Reference: BMJ. — 2010. — Vol. 340. — b5349. doi: 10.1136/bmj.b5349.
Keywords: Atomic bomb, Hiroshima, Nagasaki, 50-years follow-up
Abstract: Objective To investigate the degree to which ionising radiation confers risk of mortality from heart disease and stroke.
Design: Prospective cohort study with more than 50 years of follow-up.
Setting: Atomic bomb survivors in Hiroshima and Nagasaki, Japan.
Participants: 86 611 Life Span Study cohort members with individually estimated radiation doses from 0 to >3 Gy (86% received <0.2 Gy).
Main outcome measures Mortality from stroke or heart disease as the underlying cause of death and dose-response relations with atomic bomb radiation.
Results: About 9600 participants died of stroke and 8400 died of heart disease between 1950 and 2003. For stroke, the estimated excess relative risk per gray was 9% (95% confidence interval 1% to 17%, P=0.02) on the basis of a linear dose-response model, but an indication of possible upward curvature suggested relatively little risk at low doses. For heart disease, the estimated excess relative risk per gray was 14% (6% to 23%, P<0.001); a linear model provided the best fit, suggesting excess risk even at lower doses. However, the dose-response effect over the restricted dose range of 0 to 0.5 Gy was not significant. Prospective data on smoking, alcohol intake, education, occupation, obesity, and diabetes had almost no impact on the radiation risk estimates for either stroke or heart disease, and misdiagnosis of cancers as circulatory diseases could not account for the associations seen.
Conclusion: Doses above 0.5 Gy are associated with an elevated risk of both stroke and heart disease, but the degree of risk at lower doses is unclear. Stroke and heart disease together account for about one third as many radiation associated excess deaths as do cancers among atomic bomb survivors.
URL: http://www.bmj.com/content/340/bmj.b5349
Author: D. Bazyka, K. Loganovsky, I. Ilyenko et al.
Reference: Abstracts of the 15th World Congress of Psychohysiology «The Olympics of the Brain — IOP2010», Budapest, Aug 30 – Sep 04, 2010 // International Journal of Psychophysiology. — 2010. — Vol. 77, № 3. — P. 0251.
Abstract: Following low-level internal and external radiation, mild cognitive disorder and abnormal EEG increased, whereas verbal short-term memory, verbal learning, and proactive interference of verbal information deteriorated.
URL: http://www.ncf-net.org/radiation/aPsychophysiologicalNeuroimmuneGeneExprCFSandLDradiation.pdf
Title: Distant radiological consequences of the Chernobyl nuclear accident for the population of the Bryansk region: solid cancers
Author: Ivanov V.K., Drynova N.N., Vlasov O.K., Schukina N.V., Efendiev V.A.
Reference: Radiation and Lisk 2008、vol.17,No.4
Keywords: attributive risk, solid cancers, the population of the Bryansk region
Abstract: Prognosis of induction of radiation related solid cancers in population of the Bryansk oblast was made with the use of UNSCEAR model. It was found that the increase in the rate of all solid cancers could be up to 3 %. Calculated and actual data of the National Radiation and Epidemiological Registry were in good agreement. The contribution of radiation to increase of the rate of breast cancer in young women can be up to 10 %.
URL: http://cyberleninka.ru/article/n/otdalennye-radiologicheskie-posledstviya-avarii-na-chernobylskoy-aes-dlya-naseleniya-bryanskoy-oblasti-solidnye-raki
Author: A.I. Nyagu, K.N. Loganovsky, K.L. Yuryev, L.L. Zdorenko
Reference: International Journal of Radiation Medicine. — 1999. — Vol. 2, № 2. — P. 3–24.
Reference: Радиация и риск (Radiation and Risk) (Бюллетень Национального радиационно-эпидемиологического регистра) 2006 Том: 15 Номер выпуска: 1-2
Abstract: Avdeenko U.P.: Morphological characteristics of the thyroid gland of the adult population of St. Petersburg. dissert.. Candidate of medical sciences. St. Petersburg, 2003.
Averianova M.Yu., Strongin, L.G., Izmailov S.G., Averianov Yu.A.: Thyroid disease (diagnosis, clinical features, treatment). Nizhny Novgorod, 2002. 96.
Adoshina K.P.: Features of disability, medico-social assessment and rehabilitation of the liquidators of the Chernobyl nuclear power plant. dissert. Candidate of medical sciences. St. Petersburg, 2003. 22с. …
URL: http://cyberleninka.ru/article/n/postupleniya-v-bibliograficheskuyu-informatsionnuyu-bazu-mrnts-ramn-chernobyl-v-2004-godu
Reference: Радиация и риск (Radiation and Risk) (Бюллетень Национального радиационно-эпидемиологического регистра) 2002 Номер выпуска: 13
Abashova E.V.: Children’s health in the area of accomodation of NPP: dissert. cand.med.sci.
Abrosimov A.Yu., Il’in A.A., Rumyantsev P.O., Severskaya N.V., Dvinskikh N.Yu., Terent’yev R.O.: Clinic-morphological characteristics of follicular thyroid tumors in young people living in the contaminated areas / Problems of Endocrinology.
Abugova M.A.: Change of threshold of pain sensitivity in patients with depersonalization, depending on the effect of therapy / / Social and Clinical Psychiatry. – 2001. – № 3. – S. 14-17.
URL: http://cyberleninka.ru/article/n/postupleniya-v-bibliograficheskuyu-bazu-dannyh-mrnts-ramn-chernobyl-v-2001-godu
