Assessment of the health of children and adolescents living in the contaminated areas of the Kaluga region as a result of the accident at the Chernobyl nuclear power plant, using a computer automated system of summarizing medical dosimetry Inspections

Author: V.V. Stukalova

Reference: Dissertation, Obninisk, 2002

Keywords: health care, low-dose radiation, monitoring

Abstract: Modern radio-biological concept of low doses of ionizing radiation and the organization of the study of radiation accidents (literature review)

1.1. The impact of low-dose radiation on biological objects and systems

1.2. Epidemiological data on the effects of low-dose radiation

1.3. Organizational aspects of health care provision in radiation accidents and conducting of long-term monitoring of affected individuals

Radioecological situation in the Kaluga region after the Chernobyl accident, the radiation dose of the population. Total volume of the research methodology and analysis of the dynamic monitoring of the health of the pediatric population in the years 19921996. (Materials and Methods) …

URL: http://www.dissercat.com/content/otsenka-sostoyaniya-zdorovya-detei-i-podrostkov-prozhivayushchikh-na-zagryaznennykh-radionuk

Reconstruction of dose and risk assessment of public exposure Chernobyl radioactive iodine in Russia

Author: I.A. Zvonova

Reference: Dissertation, doctor of technological sciences, St. Petersburg, 2003

Keywords: radio-iodine, food, environment

Abstract: The purpose of research is to develop methods and assessment of thyroid doses to the residents of Russia, exposed to radioactive iodine isotopes from the Chernobyl nuclear power plant. Studies of the incidence of thyroid cancer due to the absorbed dose to the thyroid and in the assessment of the risk of additional thyroid cancers caused by radiation. Achieving this goal is based on the results of monitoring of iodine radionuclides in the environment, food, in the human body, which was conducted in May-June 1986.

URL: http://www.dissercat.com/content/rekonstruktsiya-doz-i-otsenka-riska-oblucheniya-naseleniya-rossii-radioaktivnym-iodom-cherno

The relationship of somatic diseases and thyroid dysfunction of the liquidators of the Chernobyl accident in remote period

Author: N.L. Khrebtova

Reference: Dissertation, candidate of midical sciences, Perm, 2003

Keywords: liquidator, remote period observation, neuro-psychic analyses, algorithm

Abstract: Objectives of the study:

1. To study the overall health condition of the liquidators of the Chernobyl accident in the 1986-87 and 1988-90 in the long term (after 12-16 years), including the analysis of patterns of disease, and the nature of somatic and neuropsychiatric disease.
2. Assess the clinical condition of the thyroid system of the participants of work at Chernobyl in the long term.
3. To study the characteristics of the formation of arterial hypertension of the liquidators, the medical display of cardiovascular disease in this population.
4. To analyze the dynamics of the state of neuro-psychic sphere of liquidators of the Chernobyl accident in remote period, to identify the relationship thyroid dysfunction and neuropsychiatric status of liquidators.
5. To develop an algorithm of actions of the physician in the study of thyroid system of liquidators, management recommendations of this group of patients, and for the correction of violations.

URL: http://www.dissercat.com/content/vzaimosvyaz-somaticheskoi-patologii-i-tireoidnoi-disfunktsii-u-likvidatorov-avarii-na-chaes-

An analysis of the health effects of the Chernobyl disaster on children in Kaluga region to develop the strategy and tactics of specialized medical examination

Author: M.P. Borovikova

Reference: Dissertation, Doctor of medical sciences, Obninsk, 2004

Keywords: leukemia, solid cancer, categorization, long term analyses

Abstract:

1. The world’s first radiation accident after the accident at the Chernobyl nuclear power plant with the fallout over large areas of radionuclides of iodine and cesium, etc. (with a density of pollution in the Kaluga region up to 15 Ci/km2) was implemented at the district level of the Russian State Medical Dosimetry Registry scientifically grounded Specialized medical examination of the child population, for the analysis of individual and summary measures of health.
2. Population analysisv was carried out in the Kaluga region and the calculation of attributable risk of stochastic effects. It is shown that the lifetime risk for thyroid cancer in children was 8.25, leukemia – 1.38 and 0.75 solid cancers per 100 patients.
3. Scientifically proven lack of dependence of intense growth in overall incidence of newly diagnosed and individual classes in its structure from the value of the mean cumulative effective dose to the whole body for the first 10 years of living children in the contaminated areas of the Kaluga region.
4. Based on analysis of the demographic-epidemiological and standardized intensive indicators of newly diagnosed disease, in the dynamics between 5 and 15 years, four risk groups are defined to follow-up with intact identification of possible long-term effects of low doses of radiation.

URL: http://www.dissercat.com/content/analiz-meditsinskikh-posledstvii-katastrofy-na-chernobylskoi-aes-u-detei-kaluzhskoi-obl-dlya

Dynamics of cytogenetic damage in children and adolescents living in the contaminated areas after the accident at the Chernobyl nuclear power plant

Author: V.V. Tsepenko

Reference: Dissertation, candidate of biology, Obninsk, 2004

Keywords: chromosome aberrations, children, adolescents, frequency

Abstract:

1.1.              Spontaneous level of chromosome aberrations in the culture of human lymphocytes. 1.1.1. The frequency of unstable chromosome aberrations in the controlled groups of children and adolescents. 1.1.2. The frequency of stable chromosome aberrations in the controlled groups of children and adolescents.

1.2.             The frequency of chromosome aberrations in children and adolescents living in the contaminated areas. 1.2.1. The frequency of unstable chromosome aberrations. 1.2.2. The frequency of stable chromosome aberrations.

1.3.             The frequency of stable and unstable chromosome aberrations in prenatally exposed children.

1.4.             The frequency of chromosome aberrations in children and adolescents with a high dose of load and pathologies of the thyroid gland, living in the contaminated areas and exposed to iodine exposure as a result of the Chernobyl accident.

1.5.             Multiaberrant cells. …

URL: http://www.dissercat.com/content/dinamika-tsitogeneticheskikh-narushenii-u-detei-i-podrostkov-prozhivayushchikh-na-zagryaznen

The radiation risks of cancer incidence and cancer mortality among liquidators of the Chernobyl accident

Author: V.V. Kasheev

Reference: Dissertation, candidate of biology, Obninsk, 2009

Keywords: disease, mortality, liquidator

Abstract: In the analysis of the incidence of thyroid cancer (TC) of the liquidators of the Chernobyl accident, a significant increase in the incidence of thyroid cancer (SIR = 3.47, 95% CI: 2.80, 4.25) among liquidators, in relation to the age-standardized male population of the country, is identified. It is shown that the highest incidence rate of thyroid cancer (SIR = 6.62, 95% CI: 4.63, 9.09) are of the liquidators, who participated in the work of the 30-km zone of the Chernobyl nuclear power plant between April and July in 1986. Statistically significant dependence of incidence of thyroid cancer among liquidators with external exposure dose is not identified. …

URL: http://www.dissercat.com/content/radiatsionnye-riski-onkologicheskoi-zabolevaemosti-i-onkologicheskoi-smertnosti-sredi-uchast

Clinical and laboratory criteria to evaluate the adaptive-regulatory system of liquidators of the Chernobyl accident in remote period

Author: L.B. Drygina

Reference: Dissertation, doctor of biology, St. Petersburg, 2002

Keywords: hormonal homeostasis, liquidator, euron-specific enolase, thyroglobulin, SA 19-9, carcinoembryonic antigen

Abstract: Relationship of parameters of thyroid autoimmunity and hormonal homeostasis, allowing to predict the tendency to nodulation and hormone-genesis change in the thyroid glands of liquidators is shown. In male liquidators a complex clinical and laboratory screening, of osteotropic level, of hormones in the blood serum, was made, to examine the production of proinflammatory cytokines, indicators of mineral homeostasis, and biochemical markers of bone remodeling, revealing the state of the musculoskeletal system after exposure to complex factors of a radiation accident. Comparative analysis of the frequency of cancer in male liquidators, after long time of the accident, with the results of the study of tumor-associated antigens in peripheral blood, is shown to be effective in monitoring the neuron-specific enolase (NSE), thyroglobulin (TG), SA 19-9 and carcinoembryonic antigen (CEA). …

URL: http://www.dissercat.com/content/kliniko-laboratornye-kriterii-otsenki-sostoyaniya-adaptatsionno-regulyatornykh-sistem-u-likv

The Chernobyl disaster: biomedical regularities and prediction of the formation of thyroid disease in the population

Author: A.V. Rozhko

Reference: Dissertation, doctor of biology, St. Petersburg, 2011

Keywords: biological regularities, iodine, multiple diseases

Abstract:

1. Medical and biological regularities of formation of thyroid disease in persons exposed to large-scale radiation accidents (for example, the Chernobyl NPP), effects of iodine radionuclides tocreasing levels of various types of thyroid cancer, which is dependent on gender, age at exposure, received doses, as well as cytogenetic features of thyrocytes and their genomic instability, being also determined by the quality and quantity of conducted institutional health care operations (“active screening”).
2. After the Chernobyl disaster, in Belarus, growth of frequency of cancer and non-cancer disease of thyroid gland was registered. The greatest rise in the frequency of thyroid cancer, primary hypothyroidism, single and multinodular goiter, autoimmune thyroiditis occur among children and adolescents of the Gomel region, undergoing exposure to radionuclide iodine ….

URL: http://www.dissercat.com/content/chernobylskaya-katastrofa-mediko-biologicheskie-zakonomernosti-formirovaniya-i-prognozirovan

Instrumental restoration of information on dry or wet fallout from the Chernobyl nuclear power plant

Author: I.G.Kryukova

Reference: Dissertation, candidate of biology, Obninsk, 2008

Keywords: fallout, modeling

Abstract:

1. Methods of instrumental retrospective determination of the type of radioactive fallout (“dry” or “wet”) during the acute period after the Chernobyl accident are developed and used in the field. The maps of contaminated areas of the Bryansk region showing areas of “dry” fallout.
2. Carries out semi-empirical model for the adaptation of the contaminated areas of the Bryansk region, taking into account estimation of data on the presence of “dry” and “wet” radioactive fallout in the acute phase after the accident, and the data to individualize the value of the absorbed dose in the thyroid gland and to assess their uncertainty. Suggests verification of the possibility of applying this model in the contaminated areas of the Bryansk region. …

URL: http://www.dissercat.com/content/instrumentalnoe-vosstanovlenie-informatsii-o-nalichii-sukhikh-ili-vlazhnykh-radioaktivnykh-v

Comprehensive analysis of medical, radiation-environmental and organizational activities in the Bryansk region to minimize the consequences of the accident at the Chernobyl nuclear power plant

Author: A.D. Proshin

Reference: Dissertation, candidate of medical sciences, Obninsk, 2002

Keywords: health condition, demographic dynamics, cesium 137

Abstract:

1.Radiation-health consequences of the Chernobyl accident (review). 1.1. The role of ionizing radiation and other factors in the etiology of thyroid cancer. 2.1 The evolution of specialized medical examination in the post-Chernobyl period. Chapter 2. Materials and methods. Chapter 3. The results of their own research. 3.1. Demographic dynamics of the Bryansk region in post-accidental period. 3.2. Radiation-ecological situation in the territory of Bryansk region. 3.2.1. Evaluation of contamination of territories and basic food with cesium-137. 3.2.2. Changing the content of incorporated radionuclides, depending on the age and place of residence. 3.2.3. The assessment of individual doses. 3.3. The steps and the effectiveness of clinical examination of the inhabitants of the Bryansk region in the system of protective measures to minimize the consequences of the Chernobyl accident. 3.4. Characteristics of thyroid cancers in the population of the Bryansk region in the post-Chernobyl period.

URL: http://www.dissercat.com/content/kompleksnyi-analiz-meditsinskikh-radiatsionno-ekologicheskikh-i-organizatsionnykh-meropriyat