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カテゴリー「thyroid cancer」

A prospective study evaluating the accuracy of using combined clinical factors and candidate diagnostic markers to refine the accuracy of thyroid fine needle aspiration biopsy

Title: A prospective study evaluating the accuracy of using combined clinical factors and candidate diagnostic markers to refine the accuracy of thyroid fine needle aspiration biopsy

Author: Mathur, Aarti / Weng, Julie / Moses, Willieford / Steinberg, Seth M. / Rahabari, Reza / Kitano, Mio / Khanafshar, Elham / (…) / Kebebew, Electron

Reference: Surgery, 148 (6), p.1170-1177, Dec 2010

doi: 10.1016/j.surg.2010.09.025

Abstract: …48 Family history of thyroid malignancy 47 .069 Prior…4 .0015 Number of thyroid nodules in patients…for prior malignancy 12 Chernobyl accident 9 Occupational…conventional papillary thyroid cancer and 1.5 cm or less…

URL: http://www.sciencedirect.com/science/article/pii/S0039606010005179

Navigating Fukushima: Lessons from Chernobyl, Potential Radiation and Other Health Impacts

Title: Navigating Fukushima: Lessons from Chernobyl, Potential Radiation and Other Health Impacts
Author: An Interview with Dr. Scott Davis By Rebecca Kennedy

Reference: [PDF-548K]Apr 2011 The National Bureau of Asian Research

Abstract: …into the atmosphere at Chernobyl was substantially greater…10% of the output at Chernobyl. Although considerably less than Chernobyl, as you noted, many…likely effect will be thyroid diseases and thyroid cancer—particularly in people…

URL: http://www.nbr.org/downloads/pdfs/CHA/NBR_Davis_interview_04262011.pdf

Signal transduction in the human thyrocyte and its perversion in thyroid tumors

Title: Signal transduction in the human thyrocyte and its perversion in thyroid tumors

Author: Roger, Pierre P. / van Staveren, Wilma C.G. / Coulonval, Katia / Dumont, Jacques E. / Maenhaut, Carine

Reference: Molecular and Cellular Endocrinology, 321 (1), p.3-19, May 2010

doi: 10.1016/j.mce.2009.11.015

Keywords: Signal transduction; Thyroid carcinomas; TSH pathways; Growth factor pathway; Models; Caveats

Abstract: …it. Since many widely used “thyroidcancer cell lines have been found to derive from non-thyroid cancers ( Schweppe et al., 2008…reported to increase proliferation in thyroid cancer cell lines ( Zeng et al., 2007…

URL: http://www.sciencedirect.com/science/article/pii/S0303720709005802

A multilevel analysis of long-term psychological distress among Belarusians affected by the Chernobyl disaster

Title: A multilevel analysis of long-term psychological distress among Belarusians affected by the Chernobyl disaster

Author: Beehler, G.P. / Baker, J.A. / Falkner, K. / Chegerova, T. / Pryshchepava, A. / Chegerov, V. / Zevon, M. / (…) / Moysich, K.B.

Reference: Public Health, 122 (11), p.1239-1249, Nov 2008

doi: 10.1016/j.puhe.2008.04.017

Keywords: Belarus; Chernobyl nuclear accident; Radiation accidents; Cross-sectional studiesクロス; Psychological stress

Abstract: …is often less clear. The Chernobyl nuclear power plant disaster…radiation contamination from Chernobyl has typically failed to…outcomes other than childhood thyroid cancer. 2–4 However, the Chernobyl disaster is a…

URL: http://www.sciencedirect.com/science/article/pii/S0033350608001236

Medical monitoring results of survivors with acute radiation syndrome after Chernobyl disaster

Title: Medical monitoring results of survivors with acute radiation syndrome after Chernobyl disaster
Author: Bebeshko, Volodymyr G / Kovalenko, Alexander N / Belyi, David A / Bazyka, Dimitry A / Chumak, Anatoliy A / Sushko, Victor A / Gayiday, Vasyl M

Reference: International Congress Series, 1258, p.115-122, Nov 2003

doi: 10.1016/S0531-5131(03)01219-6

Keywords: Chernobyl accident; Acute radiation syndrome;Monitoring

Abstract: A 16-year experience in the follow-up of survivors with acute radiation syndrome (ARS) caused by the Chernobyl Nuclear Power Plant accident is presented. Oncohematological diseases and sudden cardiac death were at the top of the list as causes of death. In the 16th year after the accident, the number of people with hematological syndromes was halved in comparison with the earliest 2 years observation. The radiation-induced combined immunodeficiency of 1986–1987 decreased in the later period of recovery. Nervous system disorders were characterized by a gradual increase in organic changes in the central nervous system. Endocrine system diseases were nodular goiter, thyroid carcinoma, hypothyroidism and diabetes….

URL: http://www.sciencedirect.com/science/article/pii/S0531513103012196

La protection de la thyroïde de l’enfant et du fœtus en cas d’accident nucléaire

Title: La protection de la thyroïde de l’enfant et du fœtus en cas d’accident nucléaire
Author: Vernis, M / Hindie, E / Galle, P

Reference: Archives de Pédiatrie, 4 (5), p.473-479, May 1997

doi: 10.1016/S0929-693X(97)86679-1

Keywords: nuclear accident; thyroid cancer; child; iodide prophylaxis; iodine

Abstract: …The analysis of complications following the nuclear accidents of Marshall Islands in 1954 and Tchernobyl in 1986 has shown that newborn infants and young children have the highest risk, the main complications being cancer (papillary carcinoma) and hypothyroidism. In the most exposed areas of Bielorussia, the incidence of child thyroid cancer has been approximately multiplied by 100. On the other hand, studies of children from Utah who were contaminated after nuclear tests in the Nevada desert have shown that following mild iodine radioactive exposure, the risk is not significant. Among complications attributed to stable iodine, only those related to an oral intake over a limited period of time should be considered. On the basis of nuclear medicine experience and scientific literature, the risk can be considered as negligible in adults but not in children….

URL: http://www.sciencedirect.com/science/article/pii/S0929693X97866791

Chernobyl Studies Project: Working group 7.0, Environmental transport and health effects. Progress report, March–September 1994

Title: Chernobyl Studies Project: Working group 7.0, Environmental transport and health effects. Progress report, March–September 1994

Author: Anspaugh, L.R. / Hendrickson, S.M. [eds.]

Reference: DOE Scientific and Technical Informatio Dec 1994

doi: 10.2172/112330

Keywords: 56 BIOLOGY AND MEDICINE, APPLIED STUDIES ;22 NUCLEAR REACTOR TECHNOLOGY ;05 NUCLEAR FUELS; REACTOR ACCIDENTS; HEALTH HAZARDS; CHERNOBYLSK-3 REACTOR; THYROID; RADIATION DOSES; CHROMOSOMAL ABERRATIONS; LEUKEMIA; CHILDREN; PROGRESS REPORT

Abstract: …associated with the Chernobyl accident, and (3…broader in scope than just Chernobyl, and the agreement…a direct part of the Chernobyl Project. However…See Section 7.2F – Thyroid Studies for the resolution…childhood-thyroid cancer. III. Significant…

URL:http://www.osti.gov/bridge/product.biblio.jsp?query_id=2&page=0&osti_id=112330

Rearrangements of NTRK1 gene in papillary thyroid carcinoma

Title: Rearrangements of NTRK1 gene in papillary thyroid carcinoma

Author: Greco, A. / Miranda, C. / Pierotti, M.A

Reference: Molecular and Cellular Endocrinology, 321 (1), p.44-49, May 2010

doi: 10.1016/j.mce.2009.10.009

Keywords: NTRK1; Gene rearrangement; Papillary thyroid tumor

Abstract: …starting from papillary thyroid tumor DNA. Transforming…isolated from papillary thyroid tumors are reported in Table…radioiodine released from the Chernobyl reactor a high rate of…event in the process of thyroid carcinogenesis. Transgenic…penetrance of thyroid cancer and shortens the latency…

URL:http://www.sciencedirect.com/science/article/pii/S0303720709005565

Chromosome aberrations in lymphocytes and clastogenic factors in plasma detected in Belarus children 10 years after Chernobyl accident

Title: Chromosome aberrations in lymphocytes and clastogenic factors in plasma detected in Belarus children 10 years after Chernobyl accident

Author: Gemignani, Federica / Ballardin, Michela / Maggiani, Francesca / Rossi, Anna M / Antonelli, A / Barale, Roberto

Reference: Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 446 (2), p.245-253, Dec 1999

doi: 10.1016/S1383-5718(99)00194-1

Keywords: Chromosome aberrant cells; Lymphocytes; Clastogenic factors; Belarus; Chernobyl accident

Abstract: In 1996, 10 years after Chernobyl accident, a cytogenetic analysis was carried out to assess whether chromosome aberrant cells (CA) were still detectable in the lymphocytes and clastogenic factors (CFs) were present in the plasma of children coming from Gomel (Belarus), one of the most heavily contaminated regions. Furthermore, the possible contribution of plasmatic CFs to the amount of CA was investigated. The presence of CA was examined in the lymphocytes from 29 thyroid tumour-affected children and 41 healthy children (local controls). Thirty healthy children living in Pisa (Italy) were enrolled in the study as additional controls from an uncontaminated area….

URL: http://www.sciencedirect.com/science/article/pii/S1383571899001941

Chapter 30 – Oncogenes in Thyroid Tumors

Title: Chapter 30 – Oncogenes in Thyroid Tumors

Author: Goretzki, Peter E. / Gorelev, Victor / Simon, Dietmar / Roeher, Hans-Dietrich

Reference: Textbook of Endocrine Surgery, Jan 2005

ISBN:9780721601397

Abstract: …i.e., thyrotropin or thyroid-stimulating hormone [TSH…e.g., prevalence of thyroid cancer in Russia before and after the Chernobyl catastrophe), toxicology…roles of oncogenes in human thyroid tumors. Oncogenes Connected…

URL:http://www.sciencedirect.com/science/article/pii/B978072160139750034X

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