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Chapter 100 – Use of 131-Iodine and the Risk of Radiation Exposure: Potential Hazards to the Patient and Other People

Title:Chapter 100 – Use of 131-Iodine and the Risk of Radiation Exposure: Potential Hazards to the Patient and Other People

Author: Cappelen, Tone / Unhjem, Jan Frede

Reference: Comprehensive Handbook of Iodine, Jan 2009

ISBN:9780123741356

Keywords:

Abstract: For decades, 131I (radioiodine) has been used for the diagnosis and treatment of benign and malignant conditions of the thyroid gland. The beta particles from 131I damage and destroy the thyroid partly or completely. Radiation from 131I has the potential to induce solid cancers and leukemia, but there is no firm evidence of increased cancer risk after a diagnostic scan or treatment for hyperthyroidism. A significantly increased risk of second primary malignancies has been reported with high cumulative activities of 131I. There is no evidence that treatment with 131I is associated with infertility in female patients or birth defects in subsequent children. Age at the time of such exposure is the most important factor that influences cancer risks. The thyroid gland of children is very sensitive to radiation, and special precautions should be taken in order to minimize external exposure and contamination of children and pregnant women. Some studies recommend that when 131I is given to parents of small children, persons other than the patient should take care of the children in the first days after treatment. The International Commission on Radiological Protection (ICRP) has recommended occupational and public dose limits and dose constraints. The European Commission (EC) has suggested more detailed dose constraints for different categories of caregivers.

 

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URL: http://www.sciencedirect.com/science/article/pii/B978012374135600100X

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