Cognitive, psychological and psychiatric effects of ionizing radiation exposure
Author: D. Marazziti, S. Baroni, M. Catena-Dell’Osso, et al.
Reference: Curr Med Chem. —2012. — Vol. 19, №12. — P. 1864–1869.
Keywords: cancer, non-cancer diseases, pathophysiology
Abstract: Radiation exposure leads to an increased risk for cancer and, possibly, additional ill-defined non-cancer risk, including atherosclerotic, cardiovascular, cerebro-vascular and neurodegenerative effects. Studies of brain irradiation in animals and humans provide evidence of apoptosis, neuro-inflammation, loss of oligo-dendrocytes precursors and myelin sheaths, and irreversible damage to the neural stem compartment with long-term impairment of adult neurogenesis. With the present paper we aim to present a comprehensive review on brain effects of radiation exposure, with a special focus on its impact on cognitive processes and psychological functions, as well as on their possible role in the pathophysiology of different psychiatric disorders.
URL: http://www.ncbi.nlm.nih.gov/pubmed/22376039
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