Radiation induced cardiac valve disease in a man from Chernobyl

Title: Radiation induced cardiac valve disease in a man from Chernobyl

Author: Bose AS, Shetty V, Sadiq A, Shani J, Jacobowitz I.

Reference: J Am Soc Echocardiogr. 2009 Aug;22(8):973.e1-3.

doi: 10.1016/j.echo.2009.03.027.

Keywords: Radiation-induced valve disease; Aortic stenosis; Mitral regurgitation

Abstract: A young man presented with a new heart murmur. History revealed that the patient was from Ukraine, which was affected by the Chernobyl nuclear plant explosion in 1986. Physical examination revealed murmurs of mitral regurgitation and aortic stenosis. Transesophageal echocardiography revealed severely calcified mitral and calcified tricuspid aortic valves with mitral and aortic regurgitation and aortic stenosis. Following valve replacement surgery, pathologic examination of the valves showed severe dystrophic calcifications and changes suggestive of a chronic inflammatory process such as radiation-induced valve disease. In the absence of another etiology explaining such severe valve disease in a young man, it can only be surmised that heavy radiation exposure from the nuclear plant caused this significant valve damage.

ＵＲＬ：http://www.ncbi.nlm.nih.gov/pubmed/19647162

Daily profile of heart rate and blood pressure in liquidators of the accident at the Chernobyl nuclear power plant, in remote period

Author: Agaltsov, Mihail Viktorovich

Reference: dissert. 14.00.06 Moscow.: 2003

Keywords: Cardiology, liquidators

Abstract: Aim of our research was to create optimal complex of functional methods of studies on the cardiovascular systems of liquidators in the remote period after the accident, for diagnosis, establishment of therapeutic means, creation of dispanserisation and objectivization of solutions on a professional level.

URL: http://www.dissercat.com/content/sutochnyi-profil-serdechnogo-ritma-i-arterialnogo-davleniya-u-likvidatorov-posledstvii-avari

Mortality from cardiovascular diseases among male workers at the radiochemical plant of the “Mayak” complex

Author: M.G. Bolotnikova, N.A. Koshurnikova, N.S. Komlevaet al.

Reference: Sci. Total. Environ. — 1994. — 142: — 29–31.

Keywords: cardiovascular disease, ischemic heart disease, cerebrovascular disease

Abstract: An epidemiologic retrospective study was conducted on the basis of a personnel registry, including 9373 male workers who had started to work at the radiochemical plant during the period from 1948 to 1972, inclusive. Male mortality from cardiovascular disease proved to be 271.1 cases in 100,000 persons/year on average. The age-standardized mortality amounted to 502.5 cases in 100,000 persons/year, which is significantly lower than that of the entire male population. Regarding the structure of mortality from cardiovascular diseases in the studied male groups, the mortality rate from ischemic heart disease (IHD) was 63.7% and that from cerebrovascular disease 21.5%, compared with 57% and 30%, respectively, for the general male population. Mortality from cardiovascular diseases is lower in the study groups than in the general public and does not depend on the external gamma-irradiation dose.

URL: http://www.ncbi.nlm.nih.gov/pubmed/8178133

Neurophysiologic effects of acute and chronic low dose radiation Proceedings, 5th International Cardio Event 2013 “Cardiology Towards the Future, System Medicine”

Author: Loganovsky K.N.

Reference: Florence, Italy, January 17-19, 2013. — pp. 77–85