カテゴリー「thyroid cancer」
Title: CHARACTERISTIC CLINICAL PATTERN OF THYROID CANCER IN ADULTS IN RADIOCONTAMINATED AREAS
Author: Korenev S.V.
Reference: Journal” ВЕСТНИК РОНЦ ИМ. Н. Н. БЛОХИНА РАМН” vol. 15No.3 : 2004
ISSN: 1726-9806
Keywords: THYROID CANCER, CLINICAL PATTERN, RADIOCONTAMINATED AREAS
Abstract: Continuous rise in thyroid cancer morbidity is the most important problem of the post-Chernobyl period. We analyzed clinical features of 1185 patients who were above 18 years of age when the Chernobyl atomic station catastrophe occurred. The post-Chernobyl thyroid cancer is characterized by a higher rate of multicentric growth with specific clinical symptoms. The first sign of thyroid cancer with multicentric growth in adults is a set of symptoms including weakness, decreased abilities, fatigue, somnolence (56.5% of cases). Thyroid cancer is often associated with myoma of the womb (23.6%). The active detection strategy resulted in a dramatic rise in early thyroid cancer (pT1-2N0M0) in the region of Bryansk (86.1%) thus providing a basis for better treatment outcomes.
URL: http://elibrary.ru/item.asp?id=9024748
Title:
Author: Golivets T.P., Kovalenko B.S.
Reference: Journal” ПАЛЛИАТИВНАЯ МЕДИЦИНА И РЕАБИЛИТАЦИЯ» No.4 2011
ISSN: 2079-4193
Keywords: CANCER, THE BELGOROD REGION, THE CHERNOBYL NUCLEAR POWER PLANT ACCIDENT, LOW, MALIGNANT NEOPLASMS
Abstract:
URL: http://elibrary.ru/item.asp?id=17239200
Title: Choice of tin scope of surgical treatment in patients with thyroid can cer in radionuclide-polluted areas
Author: Korenev S. K, Pteshkov V. G., Tugai V. V.
Reference: Journal”АННАЛЫ ХИРУРГИИ” No.4 2004
ISSN: 1560-9502
Keywords: THYROID CANCER, SURGICAL TREATMENT, RADIONUCLIDE-POLLUTED AREAS,
Abstract: The rise in thyroid cancer (TC) morbidity in the radionuclide-polluted area generated a need for adequately assessing the available modalities of surgical treatment. The study covered 330 patients with TC (T12N0M0) who lived in the radionu- clide-polluted areas of the Bryansk Region. Hemithyroidectomy with isthmusectomy is the optimum scope of a surgical intervention in low-grade TC (T12N 0Mq). Organ-sparing operations resulted In a 2.7-fold reduction of the rate of postoperative complications. Thyroidectomy does not significantly increase relapse-free survival in patients with TC as compared with organ-sparing operations
URL: http://elibrary.ru/item.asp?id=17033964
Title: OVERCOMING THE EFFECTS OF THE CHERNOBYL NUCLEAR POWER STATION ACCIDENT, PROBLEMS AND PROSPECTS OF RADIATION CONTAMINATED TERRITORIES
Author: Sednev V., Ovsyanik A.
Reference: Journal «Пожары и ЧС», 129366, Moscow
ISSN: 2071-9116
Keywords: CHERNOBYL ACCIDENT, RADIATION-CONTAMINATED AREAS OF SOCIO-ECONOMIC IMPACTS, THE DEVELOPMENT OF AFFECTED AREAS
Abstract: The article assesses the outcome of the work done to eliminate on the consequences of Chernobyl accident and its impact on human health, environment and socio-economic development of territories. A quarter-century on people still need clear understanding of health, environmental and socio-economic of the disaster in obtaining answers to outstanding questions
URL: http://elibrary.ru/item.asp?id=16223613
Title: View of Pathologist on Medical Consequences of the Chernobyl Accident: Neoplasms
Author: Lushnikov E.F
Reference: Journal” МЕДИЦИНСКАЯ РАДИОЛОГИЯ И РАДИАЦИОННАЯ БЕЗОПАСНОСТЬ“53- 1 : 2008
ISSN: 0025-8334
Keywords: CHERNOBYL ACCIDENT, MEDICAL CONSEQUENCES, NEOPLASMS, THYROID CARCINOMA
Abstract: Purpose: To review medical consequences of the Chernobyl accident taking oncological morbidity and mortality in population as example. Material and methods: Data of the demographic and medical statistics of oncological morbidity and mortality as well as results of studies fulfilled by colleagues of the laboratory of pathological anatomy headed by author of the paper were used. Results: It was established that morbidity and mortality rates of malignant neoplasms that could be/not be related to consequences of the accident were varied in different regions of Russia. Completeness and reliability of the data of oncological statistics were acceptable for the public health organization but insufficient for assessment of medical consequences of the accident for past years and estimation of risks for population morbidity and mortality resulted from malignant tumors that could be induced by ionizing radiation as the statistics does not take into consideration the peculiarities of the onco-nosological forms. There were several reasons (difficulties of diagnostics, death of the majority of patients at home, lack or insufficient pre- or post-mortal morphological diagnosis verification, low quality of medical and statistical documentation) that created obstacles for improvement of the quality of medical information. More reliable data of morbidity and mortality in population exposed to the accidental radiation could be obtained from the special registry based on the information that controlled by morphological verification of diagnosis. Analysis of morbidity and mortality in accordance with the 1CD-10 can not provide any notion about relationship between pathology and various factors of accident as each of onco-nosological form has own etiological, pathogenetical, clinico-anatomical peculiarities and should be specially analyzed.
URL: http://elibrary.ru/item.asp?id=10019507
Title: THE COMPARATIVE CHARACTERISTIC OF CONDITION OF IODIC EXCHANGE OF TAMBOV REGION POPULATION OF TERRITORY POLLUTED BY RADIO NUCLIDES
Author: Bondarev Vitaliy Vladimirovich
Reference: Journal «ВЕСТНИК ТАМБОВСКОГО УНИВЕРСИТЕТА. СЕРИЯ: ЕСТЕСТВЕННЫЕ И ТЕХНИЧЕСКИЕ НАУКИ» NO.1-17: 2012
ISSN: 1810-0198
Keywords: RADIATION, RADIONUCLIDES, THYROID GLAND, ESSENTIAL MICROELEMENT IODINE, PITUITARY-THYROID SYSTEM
Abstract: The estimation of a condition of the microelement status at the inhabitants living in territory polluted by radio nuclides which was exposed to radiating influence as a result of emergency situations on the Chernobyl NPP (inhabitants of Sosnovsky and Petrovsky areas of the Tambov region) is given. During research the microelement status and a functional condition of pituitary-thyroid system has been estimated.
URL: http://elibrary.ru/item.asp?id=17686370
Title: THE COMPARATIVE CHARACTERISTIC OF CONDITION OF THYROID SYSTEM AND MICROELEMENT STATUS OF POPULATION OF TAMBOV REGION IN TERRITORY POLLUTED BY RADIO NUCLIDES
Author: Bondаrev Vitaliy Vladimirovich, Malysheva Elena Vladimirovna, Gulin Alexander Vladimirovich
Reference: Journal “ВЕСТНИК ТАМБОВСКОГО УНИВЕРСИТЕТА. СЕРИЯ: ЕСТЕСТВЕННЫЕ И ТЕХНИЧЕСКИЕ НАУКИ» No.5-16 2011
ISSN: 1810-0198
Keywords: RADIATION, RADIONUCLIDES, THYROID GLAND, ESSENTIAL TRACE ELEMENTS IODINE, PITUITARY-THYROID SYSTEM, THYROID-STIMULATING HORMONE (TSH), FREE THYROXINE (FT4), FREE THREEIODOTHYRONINE (FT3), THYROGLOBULIN (TG)
Abstract: The estimation of a condition of the microelement status at the inhabitants living in territory polluted by radio nuclides which was exposed to radiating influence as a result of emergency situations on the Chernobyl NPP (inhabitants of Sosnovsky and Petrovsky areas of the Tambov region) is given. During research the microelement status and a functional condition gipofizarno-tireoide systems has been estimated.
URL: http://elibrary.ru/item.asp?id=17069046
Title: Selection of the cohort for the long-term clinical follow-up and assessment of radiation risks for thyroid diseases under the Joint Medical Research Project conducted by Sasakava Memorial Health Foundation and MRRC of RAMS
Author: Ivanov V.K., Tsyb A.F., Pitkevich V.A., Maksyutov M.A., Маtveenko Е.G., Khvostunov I.К., Rastopchin Е.М., Sorokin V.S., Ivanov S.I., Leshakov S.Y., Shiryaev V.I., Borovikova М.P., Efendiev V.A., Kvitko B.I., Shibata Y., Yamashita S., Hoshi M.
Reference: Journal “RADIATION AND RISK” No.8 1996
doi:
Keywords: Cohort
Abstract: The description of the cohort of the children of Bryansk and Kaluga regions of Russia exposed to radioiodine in 1986 as a result of the Chernobyl accident is given in the paper. The cohort has been selected under the Joint Medical Research Project on Thyroid disease conducted by Sasa-kava Memorial Health Foundation and MRRC of RAMS for the long-term clinical follow-up of the thyroid. It comprises 3299 persons, 1187 of them are residents of Bryansk region and 2112 – residents of Kaluga region. All subjects were under 10 years old at the time of exposure. All members of the cohort have individual radiometric data for thyroid obtained in May-June of 1986. The main part of the subjects lived in the most contaminated areas of Bryansk and Kaluga regions in 1986. The preliminary evaluation of absorbed radiation doses to thyroid has been performed before the verification of incorporated activity of 131I in thyroid, dynamics of radioiodine deposits in the territory of Russia as well as specialised cross-examination of the cohort members. Analysis of the results has shown that statistical distribution of the absorbed doses of internal exposure of thyroid is close log normal distribution with mean value of 240 mGy and standard deviation of 750 mGy for Bryansk part of the cohort, and 360 mGy – for Kaluga one. In 5% of the members the absorbed radiation dose in thyroid is under 1 mGy, the maximal one is 12 Gy for the Bryansk part of the cohort and 6 Gy for the Kaluga part. One of those who were followed up within the decade after the Chernobyl developed thyroid cancer. For the next period of the follow-up by the cohort study technology radiation risks of developing thyroid cancer and non-cancer thyroid diseases are planned to be assessed.
URL: http://elibrary.ru/item.asp?id=9320742
Title: Thyroid Gland Pathology among Chernobyl NPP Disaster Fighters Living within Ozyorsk Area
Author: Rabinovich E.I., Povolotskaya S.V., Shorokhova V.B., Turdakova V.A., Egorov A.N., Ryzhova E.F., Siniborova E.A., Privalov V.A.
Reference: Journal «ВОПРОСЫ РАДИАЦИОННОЙ БЕЗОПАСНОСТИ» No.2 : 2008
ISSN: 1816-9643
Keywords:Ozyorsk, liquidator
Abstract: Relation between radioactive impact and thyroid pathology was investigated among the Chernobyl NPPdisaster fighters living within the Ozyorsk area. It was revealed that the prevalence of all thyroid illnesseswithin the group of Ozyorsk residents, who was subjected to the higher radiation risk due to the post-accidental activities in the Chernobyl NPP, did not differ from that one among the population not subjected toany man-induced radiation impact. Among male fighters there were no differences noted for any nosologicillness form. At the same time among females a significant excess of nodular goiter is revealed comparedwith the control group (OP =1.5 at 95% confidence limit 1.0-2.3). This difference is conditioned by thesub-group of females subjected in the childhood to the radiation impact of the body burden radionuclides,particularly 131I due to residence in the area of Mayak PA influence. It is demonstrated that the prevalenceof thyroid pathology is significantly related to the non-radiation risk factors: sex (2.5 times higher forfemales than for males) and age (1.6 times higher for persons after 60 years old), which complys that is incompliance with published data.
URL: http://elibrary.ru/item.asp?id=11659551
Title: Problems of iodine prophylaxis in Russia in case of radiation accident
Author: Iljin L.A., Lyaginskaya A.M., Vasilenko I.Yu., Osipov V.A., Ermalitsky A.P., Savkin M.N., Grachev M.I., Avetisov G.M.
Reference: Journal «МЕДИЦИНА КАТАСТРОФ» No.: 1-2 : 2006,
doi:
Keywords: POTASSIUM IODIDE, IODINE PROPHYLAXIS, RADIOACTIVE IODINE, THYROID GLAND
Abstract: The authors describe validity of the principles of the existing iodine prophylaxis in this country, levels of intervention and adopted doses of protective preparations from the point of view of modern knowledge. They state that possibility of cancer diseases progress may be reduced or even totally prevented using iodine pro-phylaxis, and to the larger extent using it in combination with other protective measures; the main principle of iodine prophylaxis must be an achievement of a ma-ximum effect using minimum doses of potassium iodide for each age cohort.
URL: http://elibrary.ru/item.asp?id=11601306
