The health of children exposed to radiation as a result of the disaster at the Chernobyl nuclear power plant

Author: V.N. Doroshenko

Reference: Dissertation, Koscow, 2005

Keywords: cancer, non-cancer disease, children

Abstract: In the Bryansk region until 1991 (the latent period after the disaster at the Chernobyl nuclear power plant) spontaneous cancers of the thyroid gland were recorded among children. In the period 1992 – 1999 years. thyroid cancer children of the Bryansk region ranged from 0.96/100 thousand children in 1992 to 2.6 – in 1994 and was higher (P <0.05) than data in Russia (from 0.08 in 1992 to 2.6 in 1997), mainly due to the increase of this disease among children aged 10-14 living in areas with a density of contamination by 137Cs above 5 Ci / km. In the condition of iodine deficiency, doses of radioiodine to the thyroid gland by an average of more than 400 mGy make a significant contribution to the formation of non-toxic diffuse goiter in children.

URL: http://www.dissercat.com/content/sostoyanie-zdorovya-detei-podvergshikhsya-radiatsionnomu-vozdeistviyu-v-rezultate-katastrofy

Characteristics of thyroid cancers in the area affected by the Chernobyl accident (1986-2006 year).

Author: V.P. Troshin

Reference: Dissertation, doctor of medical sciences, St. Petersburg, 2009

Keywords: iodine deficiency, age groups

Abstract: The purpose of this paper is the comprehensive study of thyroid disease and, above all, cancers of the thyroid gland on the basis of the study of surgical material for 20 years after the Chernobyl accident in the Bryansk region under the combined effect of low doses of radiation to the thyroid and iodine deficiency. For the first time the dissertation shows the dynamics of thyroid pathology, in particular, the papillary thyroid cancer in different age groups in the area affected by the Chernobyl disaster, over the twenty-year period. …

URL: http://www.dissercat.com/content/kharakteristika-tireoidnykh-rakov-v-regione-postradavshem-ot-avarii-na-chernobylskoi-aes-198

The long-term (remote) effects of man-made iodine-131 on thyroid gland in childhood

Author: E.F. Ryzhova

Reference: Dissertation, candidate of medical sciences, Chelyabinsk, 2003

Keywords: child, iodine 131

Abstract: The problem of thyroid disorders, induced by radiation, has become particularly relevant after the accident at the Chernobyl nuclear power plant, where large groups of the population have been exposed to and incorporated external sources of radiation, including iodine-131; to a factor of iodine deficiency joins the radiation factor. Over the past few years in Belarus, Russia and Ukraine, a lot of work on the identification and treatment of diseases of the thyroid has been done, which results in unique information on the problem. The largest number of studies devoted to thyroid cancer (L.N.Astahova, 1996; E.P.Demidchik et al., 1996; E.G.Matveenko et al., 1996). Also of importance in clinical practice are non-tumoral thyroid disease, occurring many times more than cancer. They lead to severe dysfunction of the thyroid, causing such severe manifestations of it as thyrotoxic myocardial with severe rhythm disorders, disorders of calcium metabolism leading to osteoporosis, a violation of the psyche with the loss of interest in life and decreased intelligence, the progression of atherosclerosis in ultimately leads to reduced quality of life. …

The purpose of the work: Identification of the relationship of thyroid disease with an extended irradiation with iodine-131 in childhood, according to a comprehensive survey in the remote period after the man-made radiation.

URL: http://www.dissercat.com/content/otdalennye-effekty-tekhnogennogo-oblucheniya-shchitovidnoi-zhelezy-iodom-131-v-detskom-vozra

The assessment of individual doses of thyroid cancer of the population of Kaluga region as a result of direct effects of the Chernobyl accident, methodical and programmatic explanation

Author: E.K. Yaskova

Reference: Dissertation, candidate of biology, Obninsk, 2001

Keywords: exposure dose

Abstract: Review of this literature shows that, although 15 years have passed since the Chernobyl accident, the problem of adequate assessment of the level of exposure of the thyroid with radioactive iodine in the population living in the territory of the former USSR, is still quite urgent. This explains the large flow of scientific publications, presentations and discussions on this subject in recent years, as correct assessment of the initial dose-step in addressing many of the medical, epidemiological, social and other problems. In the Kaluga region the initial dose assessment was made in 1986 immediately after the primary direct measurements collected as a result of radiological survey of the population in May of the same year. In the absence of reliable information about the required environmental parameters of the formation of exposure, dose calculation was carried out by a conservative scheme based on the following assumptions: a single fallout on April 27, the earliest starting date of grazing (until April 27), the presence of countermeasures, from May 10 .. .. The aim of this work – revaluation of individual thyroid doses to the population of the surveyed areas of Kaluga region, taking into account new data on factors of the formation of exposure.

URL: http://www.dissercat.com/content/otsenka-individualnykh-doz-oblucheniya-shchitovidnoi-zhelezy-u-naseleniya-kaluzhskoi-oblasti

Features of cardiac arrhythmias in patients with various diseases of the thyroid gland

Название: Особенности нарушений сердечного ритма у лиц с различными заболеваниями щитовидной железы

Автор: Трофименко, Эдуард Валентинович

Ссылка: 2005 Москва тема диссертации и автореферата по ВАК , Трофименко, Эдуард Валентинович

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Author: E.V. Trofimenko

Reference: Dissertation, Moscow, 2005

Keywords: non-cancer diseases, cardiac arrhythmia

Abstract: In recent years a steady upward trend in the number of patients with various thyroid diseases, the prevalence of disease among the people of different countries varies between 2.1 – 4.2% [139, 260], has been witnessed. Actuality of the problem is caused not only by widespread of this disease, but also by the occurrence in mainly in young adults (from 18-20 to 40-50 years), and fairly rapid defeat of various human organs and systems [111, 139]. By the end of the first decade after the Chernobyl accident there is a significant increase in the incidence of thyroid cancer, diffuse toxic goiter and hypothyroidism [27, 41, 42, 68, 88, 167]. Considering the relatively large percentage of medium-and long-lived isotopes of iodine in the overall spectrum of pollution, it can be assumed that the problem is to continue in the coming decades. Consequently, the problem of adverse long-term consequences of environmental disasters not only has medical value, but also is extremely urgent social problem. …

The purpose of research: To study the features of cardiac arrhythmia, a condition of the central hemodynamics in patients with various diseases of the thyroid gland, depending on the functional state of the pituitary-thyroid system.

URL: http://www.dissercat.com/content/osobennosti-narushenii-serdechnogo-ritma-u-lits-s-razlichnymi-zabolevaniyami-shchitovidnoi-z

Arterial hypertension, dysfunction of thyroid and R-proteins in liquidators of the accident at the Chernobyl nuclear power plant (based on many years of observation)

Author: M.V.Novikov

Reference: Dissertation, candidate of medical sciences, Kursk, 2002

Keywords: liquidators, R-protein, arterial hypertension

Abstract: Some medical aspects of the accident at the Chernobyl nuclear power plant (literature review). 1.1. Biological effects of low-dose radiation and cardio vascular system. 1. 1.2 The accident at the Chernobyl nuclear power plant and the state of the thyroid system 1.3 R – protein, a marker of maladjustment of the body 2. Materials and methods of research. 2.1. Clinical characteristics of the persons surveyed 2.2. Methods of echocardiography 2.3. The study of the thyroid gland 2.4. Determination of R – proteins in blood serum. 3. The results of their research. 3.1. Arterial hypertension in liquidators of the accident at the Chernobyl nuclear power plant 3.1.1. Morphofunctional cardiac parameters in patients with arterial hypertension, diagnosed in the early stages after the accident. 3.1.2. Morphofunctional cardiac parameters in patients with arterial hypertension, diagnosed in the later stages after the accident 3.2. Functional status and morphological changes of the thyroid gland in the liquidators of the Chernobyl accident. 3.3. Determination results of R – proteins in blood serum in the liquidators 77 3.4. Adaptin in the treatment of arterial hypertension in the liquidators of the Chernobyl accident.

Aim of research: To establish dynamics of arterial hypertension of the liquidators and to find out, on the basis of the retrospective analysis, the status of the thyroid gland and the regulatory R- proteins in the early period after the accident, according to long-term clinical studies of the liquidators of the Chernobyl accident.

URL: http://www.dissercat.com/content/arterialnaya-gipertoniya-disfunktsiya-shchitovidnoi-zhelezy-i-r-belki-u-likvidatorov-posleds

Mathematical analysis, with forecasting, of the morphofunctional state of the thyroid gland in terms of modeling of emergency situations in radiation hazardous objects

Author: E.N. Shestakova

Reference: Dissertation, candidate of technical sciences, Voronezh, 2007

Keywords: morpho-functional state, forecast, low dose radiation

Abstract: Recently, more and more attention of scientists is focused to the studies of the effects of radiation in low doses. This question interests not only physicians, but also responsible and official persons taking important social, economic and political decisions. The fact is that, as a result of the accident at the Chernobyl nuclear power plant, were formed not only areas with high levels of radiation (the thirty-kilometer zone around the plant) but there were also “spots” of contamination. Moreover, the problem of low-dose radiation has gone beyond our country and become of global character (Frolov, 1998; Burlakov EB, 1996; Tsib AF, 2005) …

Aim of research: Evaluation of morpho-functional state of the thyroid gland with forecast of long-term (remote) effects of post-radiation damage by ionizing radiation in a wide range of parameters of low doses.

URL: http://www.dissercat.com/content/matematicheskii-analiz-s-prognozirovaniem-morfofunktsionalnogo-sostoyaniya-shchitovidnoi-zhe

The development of differentiation programs for the prevention and rehabilitation of children with diseases of the thyroid gland, including those living in the contaminated areas with radionuclides

Author: L.V. Shiryaeva

Reference: Dissertation, candidate of medical sciences, Moscow, 2006

Keywords: iodine deficiency, ioduria

Abstract: Radiation damage to the thyroid gland is one of the most serious consequences of the Chernobyl accident. Today, growth of thyroid cancer in people who were exposed in childhood [93, 9.4], is convincingly proven. On dose dependence of risk of developing thyroid cancer, also discussion on issues on increase of benign thyroid pathology …

Aim of research: To develop and demonstrate the effectiveness of program of preventing iodine deficiency and rehabilitation from iodine deficiency disorders, based on studis of thyroid status, ioduria and other microelementosis in children, including those living in “contaminated” areas with radionuclides due to the Chernobyl accident.
URL: http://www.dissercat.com/content/razrabotka-differentsirovannykh-programm-profilaktiki-i-reabilitatsii-detei-s-zabolevaniyami

Dynamics of state of thyroid gland in the residents of St. Petersburg exposed to ionizing radiation during their childhood and adolescence as result of the accident at the Chernobyl nuclear power plant

Author: V.V. Smirnov

Reference: Dissertation, candidate of medical sciences, St. Petersburg, 2006

Keywords: children, adolescence

Abstract: Aim of study – To study the dynamics of the state of the thyroid gland in residents of St. Petersburg exposed to ionizing radiation during childhood and adolescence as a result of the accident at the Chernobyl nuclear power plant.

Objectives of study: To study the dynamics of changes in the thyroid gland and the clinical signs of its functional status in patients exposed to ionizing radiation during childhood and adolescence as a result of the accident at the Chernobyl nuclear power plant. …

URL: http://www.dissercat.com/content/dinamika-sostoyaniya-shchitovidnoi-zhelezy-u-zhitelei-sankt-peterburga-podvergshikhsya-vozde

Thyroid gland: age-concerned features of the structure, and latent pathology

Author: T.S. Mukhina

Reference: Dissertation, candidate of medical sciences, Volgograd, 2008

Keywords: age dependence, morphology, structural features

Abstract: Increased incidence of thyroid cancer in many regions of Russia determines the relevance of the study of regional structural features of the body and the clinicopathologic features of benign and malignant tumors, of which differential diagnosis in preoperative stage can be extremely difficult (Romanchishen AF, 1992; Paches AI, Propp PM, 1995; Khmelnitsky OK, 2002). Especially, interest in the problems of thyroidology increased in the period after the accident at the Chernobyl nuclear power plant. Urgent study of radiogenic thyroid cancer became highly actual, for which the position remains still controversial (Lushnikov EF Tsib AF, Yamashita, S., 2006). …

The purpose of the study: To determine 1.the structural features of the thyroid gland in the mature, older and old age and 2. morphological features of latent disease, on the basis of complex morphological and morphometric research.

URL: http://www.dissercat.com/content/vozrastnye-osobennosti-stroeniya-i-latentnaya-patologiya-shchitovidnoi-zhelezy