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カテゴリー「thyroid cancer」

Clinical and laboratory criteria to evaluate the adaptive-regulatory systems in the liquidators of the Chernobyl accident, in remote periods

Author: L.B. Drygina

Reference: Dissertation, 2002

Keywords: liquidators

Abstract: Development of clinical and laboratory criteria to evaluate the adaptive-regulatory system in liquidators of Chernobyl accident, in remote period, for the solutions of diagnostic, prognostic problems. To these days, medical care to the liquidators of the of the Chernobyl accident (LPA) remains one of the national objectives (Nikiforov, AM, 1996; Tsib AF, 1998; Lushnikov. F. et al, 1999). The total number of liquidators in Russia is more than 300 thousand people. According to the Russian State Medical Dosimetry Registry (RSMDR), epidemiologically significant increase in classes of disease such as cardiovascular system, digestive system, endocrine system, diseases of musculoskeletal system and connective tissue (Shantyr II and others, 1996) are registered in the liquidators. In remote periods after the Chernobyl accident, risk of destructive autoimmune processes (Estinbeeva MJ, 994) and solid neoplasms (Ivanov VK et al, 1999) may increase …

URL: http://www.dissercat.com/content/kliniko-laboratornye-kriterii-otsenki-sostoyaniya-adaptatsionno-regulyatornykh-sistem-u-likv

Comparative assessment of indicators of overall level and patterns of disease with cytogenetic indices in children and adolescents living in the contaminated areas of the Kaluga Region after the accident of the Chernobyl nuclear power plant

Author: N.O. Omapaskhabov

Reference: Dissertation, 2007

Keywords: demography, somatic abnormalities, digestive system

Abstract: For the first time, a comprehensive comparative evaluation is carried out of the dynamics of demographic indicators, indicators of the overall level and structure of newly diagnosed disease, as well as cytogenetic indices in child population living for 20 years in the contaminated areas following the accident of the Chernobyl nuclear power plant. Implements, in the initial -“iodine”- period of the Chernobyl accident, direct measurements of absorbed doses of the thyroid gland (TG) in children of Zhizdra area, allowing, for the first time, to evaluate the observed functional changes in the thyroid depending on the individual doses of incorporated radionuclides of iodine. Determines the role of cytogenetic damage in the development of somatic abnormalities in children with elevated levels of chromosomal aberrations. Especially in prenatally irradiated cases, morphological and functional changes in the thyroid gland diseases in the respiratory and digestive system, are more often encountered. The results obtained in general: Materials of the research formed the basis for the planning of socio-economic measures and medical administration of the Kaluga region in the contaminated areas after the Chernobyl accident …

URL: http://www.dslib.net/radio-bio/sravnitelnaja-ocenka-pokazatelej-obwego-urovnja-i-struktury-zabolevaemosti-s.html

The incidence of malignant neoplasms among members of liquidation of the Chernobyl nuclear power plant accident

Author: A.R. Islamova

Reference: Dissertation, 2004

Keywords: men, women, different characteristics, health conditions

Abstract: The accident at the Chernobyl nuclear power plant, is unprecedented in scale of disaster, which resulted in succession of combined effects of a number of pathogenic factors to a huge population of people, which, in the first place, is attributed to ionizing radiation. Thus one of the major social object is to monitor the demographic-medical situation in individual populations. The most exposed and one of the largest categories of the population affected by the Chernobyl accident are the so-called “liquidators”. Majority of liquidators are men. At the same time, about 6,000 women who took part in liquidation of the Chernobyl accident are registered in the Russian State Medical Dosimetry Registry (RSMDR). These women are group of people with certain conditions and doses of external and internal exposure, initial state of health and other characteristics that are different from those of the male population of the liquidators and require further study and analysis.

URL: http://www.dissercat.com/content/zabolevaemost-zlokachestvennymi-novoobrazovaniyami-uchastnits-likvidatsii-posledstvii-avarii

Endemic goiter in children

Author:N.V. Bolotova

Reference: Dissertation, 1995

Keywords: endemic goiter, micronutrient metabolism

Abstract: To study the clinical course and to develop methods to predict the developmen of endemic goiter in children, on the basis of a comprehensive assessment of micronutrient metabolism and functional activity of the thyroid ‘gland –
URL: http://medical-diss.com/medicina/endemicheskiy-zob-u-detey

The Chernobyl catastrophe

Author: A.V. Rozhko

Reference: Dissertation, 2011

Keywords: medical treatment, reliable methods, epidemiology

Abstract: The assessment, obtained by the above mentioned methods, to determine quantities of excessive risk, depending on the dose of the thyroid gland, is not considered to be reliable. The most accurate is to be the one based on analytical cohort, whose number is limited (UNSCEAR 2000). Therefore, it requires further well-designed epidemiological studies of radiation, in which the values ​​of 1. individual doses to members of the cohort and 2. a comparison to an adequate control group of unexposed persons are considered …

URL: http://www.dissercat.com/content/chernobylskaya-katastrofa-mediko-biologicheskie-zakonomernosti-formirovaniya-i-prognozirovan

Development and application of methods of individual retrospective dosimetry of the population to assess the impact of large-scale radiation accidents

Author: V.F. Stepanenko

Reference: Dissertation, 2009

Keywords: dosimeter,

Abstract: The problems associated with the management and mitigation of the accident at the Chernobyl nuclear power plant (decision-making, adequate preventive measures and medical treatment, radiation-epidemiological assessment), since the date of the start of this study, in both the early period after the accident and in the subsequent years, it has been demanding an appropriate dosimetric security.

URL: http://knu.znate.ru/docs/index-442776.html

Features of health of children from areas with ecological trouble

Author: L.A. Sheplyagina

Reference: Dissertation, 1995

Keywords: health problems, irrational economic and domestic activities

Abstract: Recent years have been characterized by negative tendencies in the health of children: there is steady increase in disease, especially in its chronic form … Among the many factors, affecting the health of the younger generation, are those inducing tense environmental conditions in many regions of Russia. As a result of many years of irrational economic and domestic activities in, nature have accumulated hundreds of harmful substances …. Health problems, associated with industrial pollution, deepened by the Chernobyl accident, is seen as results of radio-contamination in 17 regions of Russia.

URL   http://inim-rao.ru/mode.7635-item.83342-type.html

Scientific – methodological bases to evaluate individually absorbed doses to the thyroid gland in the population after a major radiation accident

Author: S.M. Shinkarev

Reference: Dissertation, 2009

Keywords: absorbed doses

Abstract: Development of scientific – methodological bases of estimation of individually absorbed doses of radiation (radioactive isotopes of iodine) in the thyroid gland as results of operational radiometric survey of the population at large radiation accident. For example: the inhabitants of Belarus after the Chernobyl accident.
URL: http://www.dissercat.com/content/nauchno-metodicheskie-osnovy-otsenki-individualnykh-pogloshchennykh-doz-v-shchitovidnoi-zhel?_openstat=cmVmZXJ1bi5jb207bm9kZTthZDE7

Thyroid disorders in children exposed to radiation from the accident at the Chernobyl nuclear power plant

Author: I.N. Yakovleva

Reference: Dissertation, 2008

Keywords: nontoxic goiter, auto-immune thyroiditis, thyroid cancer

Abstract: The aim of the study is to assess the characteristics of thyroid disease (diffusion-nontoxic goiter, auto-immune thyroiditis, thyroid cancer) in children exposed to ionizing radiation as a result of the Chernobyl accident and living in iodine deficient areas, from the point of view of their prevalence, etiology and pathogenesis, reactivity changes occurring in the various segments of the child’s adaptive system… to justify the tactics of treatment and prevention of this disease.
URL: http://www.mif-ua.com/archive/article/7765

Thyroid cancer in children and teenagers in the conditions of iodine deficiency and radiation pollution

Author: D.E. Shilin

Reference: Dissertation, 2002

Keywords: perinatal stage, iodine deficiency

Abstract: The urgency of the problem. The diverse thyroid pathology has a leading position in the structure of endocrine diseases in humans, beginning to form already in childhood and adolescence. Diseases of thyroid gland (TG) are distributed especially in regions with iodine deficiency in the biosphere. Endemic goiter and other health disorders, related to iodine deficiency, present severe medical and social problem, which has been intensively studied in the last decade in Russia and abroad. New indicators and criteria of severity of the disease (WHO, 1994) are developed and effectively used, along with the recommendations of physiological needs of micronutrients (WHO, 1996). Negative impact on the child’s body with deficiency of thyroid hormones caused by even a slight decrease in the supply of iodine, is proven, especially in the perinatal stage of development.
URL:  http://leb.nlr.ru/edoc/58274/

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