Effects of prenatal brain irradiation as a result of the Chernobyl accident
Author: A.I. Nyagu, K.N. Loganovsky, R. Pott-Born et al.
Reference: International Journal of Radiation Medicine. — 2004. — Vol. 6, № 1–4. — P. 91–107.
Keywords: Chernobyl accident, brain damage in utero, dosimetry, psychometry, neuropsychiatric and psychological disorders.
Abstract: One of the grave consequences of the Chernobyl accident was the in utero irradiation of children. It was therefore important to study possible effects of prenatal irradiation resulted from the Chernobyl accident on neuromental health of the in utero irradiated children. A cohort of 154 children born between April 26th,1986 and February 26th,1987 to mothers who had been evacuated from Prypiat to Kiev,and 143 classmates from Kiev were examined. The Wechsler Intelligence Scale for Children (WISC),the Achenbach and Rutter A(2) tests were used for the children. School performance was also assessed. Mothers were examined with the verbal subscale of the Wechsler Adults Intelligence Scale (WAIS),the Zung Self-Rating Depression Scale (SDS),PTSD scales (Impact of Events Scale and Irritability,Depression,Anxiety Scales) and the General Health Questionnaire (GHQ-28). Neuropsychiatric diseases were diagnosed according to ICD-10. Individual dose reconstruction of the children exposed in utero was carried out considering internal and external exposure. The ICRP Publication-88 was applied for calculation of effective fetal, brain and thyroid internal doses for children of both groups. The mean effective fetal equivalent doses (M±SD) in the exposed group is 65.4±33.9 mSv and in the control group 1.2±0.3 mSv. Prenatal equivalent brain doses were 19.2±11.3 mSv and 0.8±0.2 mSv for the exposed and control groups,respectively. Thyroid doses in utero were 760.4±631.8.1 mSv and 44.5±43.3 mSv for the exposed and control groups,correspondingly. There were 20 children from Pripyat town (13.2%) who had been exposed in utero in total doses >100 mSv and there were 52 children from Pripyat town (33.8%) who had been exposed in utero to thyroid doses >1 Sv. The prenatally exposed children show significantly more diseases of the nervous system and mental disorders. Significant differences on intelligence and emotional and behavioral
disorders of exposed children in comparison to the control group were revealed….
URL: http://www.mns.gov.ua/files/rm/PDF/6_15.pdf
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