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Epidemiological aspects of radiation carcinogenesis

Title: Epidemiological aspects of radiation carcinogenesis

Author: Tsyb A.F., Ivanov V.K., Biryukov A.P., Efendiev V.A.

Reference: Radiation and Lisk 1995 No.6

Keywords:

Abstract: An effort by the authors of this review was made to combine results of activity of the great majority of research workers in different lines. In this connection the work presented does not raise the problem of comprehensive description of radiation carcinogenesis throughout its variety and complexity. It is the authors opinion that even a cursory analysis conducted on all radiation-dependent problems of carcinogenesis will provide a better view of basic directions of scientific-practical activity aimed at studying the epidemiological peculiarities of radiation-induced malignant growth. A series of questions, for example, the theory of carcinogenesis is presented very schematized and meant for the most diverse sections of readers. In addition the volume of publication does not allow to discuss all types of malignant neoplasms developing after radiation action, therefore in the text the data about only so-called solid tumours are listed among which particular emphasis has been placed on localizations having the most evident connection with the action of ionizing radiation. Epidemiological features of developing malignant neoplasms under the action of ionizing radiation, one of the factors of the environment taking part in forming the current carcinogenic situation, are discussed extensively.

URL: http://cyberleninka.ru/article/n/epidemiologicheskie-aspekty-radiatsionnogo-kantserogeneza-nauchnyy-obzor

 

Bibliography of publications on the medical aspects of mitigating the consequences of the Chernobyl accident, published in 2006

Reference:  Радиация и риск (Radiation risk) (Bulletin of the National Radiation and Epidemiological Registry) Year: 2008, Volume: 17, Issue: 1

URL: http://cyberleninka.ru/article/n/bibliografiya-publikatsiy-po-meditsinskim-aspektam-smyagcheniya-posledstviy-chernobylskoy-avarii-vyshedshih-v-2006-g

The problem of thyroid cancer in Russia after the Chernobyl accident: evaluation of radiation risks 1991-2008.

Title: The problem of thyroid cancer in Russia after the Chernobyl accident: evaluation of radiation risks 1991-2008.

Author: Ivanov V.K., Tsyb A.F., Maksyutov M.A., Tumanov K.A., Chekin S.YU., Kascheev V.V., Korelo A.M., Vlasov O.K., Schukina N.V.

Reference: Radiation and Lisk 2010 No.3

Keywords: Chernobyl accident,   territory contaminated with radionuclides,    Population,   thyroid cancer,   incidence of disease,   crude incidence rate,   standardized incidence ratio,   excess relative risk

Abstract: Joint analysis of thyroid cancer incidence in Bryansk, Kaluga, Oryol and Tula oblasts from 1981 through 2008 was made for the first time. The average size of population of the oblasts in those years was 5.1 million people. According to data of the National Radiation and Epidemiological Registry 9120 thyroid cancer cases were detected for that period. Mean-rayon thyroid doses were used for the analysis. Affected rayons of Bryansk, Kaluga, Oryol and Tula oblasts were arranged into 4 groups in accordance with radiation dose.

URL:

http://cyberleninka.ru/article/n/problema-raka-schitovidnoy-zhelezy-v-rossii-posle-avarii-na-chernobylskoy-aes-otsenka-radiatsionnyh-riskov-period-nablyudeniya-1991-2008

 

Assessment of radiation risks of cancer morbidity solid cancers among liquidators of consequences of the Chernobyl disaster

Title: Assessment of radiation risks of cancer morbidity solid cancers among liquidators of consequences of the Chernobyl disaster

Author: Ivanov V.K., Rastopchin E.M., Gorskiy A.I., Maksyutov M.A., Matyash V.A., Tsyb A.F.

Reference: Radiation and Lisk 2001 No.12

Keywords: solid cancers, liquidators

Abstract: The paper provides analysis of information about solid cancer incidence among liquidators of the Chernobyl accident accumulated in the Russian National Medical and Dosimetric Registry (RNMDR) from 1986 to the beginning of 1997. The RNMDR contains individual dosimetric data and results of annual medical examinations of liquidators living in the territory of the Russian Federation (174916 persons by the beginning of 1999). Consideration is given to male liquidators who had no cancer before entering the 30-km zone around the Chernobyl NPP and for whom information was available about date of birth, date of arrival to the zone, duration of stay in the zone and data of medical examinations. The number of liquidators meeting these requirements is 160564, which accounts for about 90% of all liquidators registered in the RNMDR. For most of liquidators (70%) the Registry database contains information on external radiation dose received during their stay in the 30-km zone. The mean dose in this study cohort is 0.1 Gy, the mean age at the time of the first arrival in the zone is 34 years and the total number of accumulated person-years is 1353935. The cohort of liquidators is briefly described and the cancer incidence rates are compared in liquidators and the population of Russia as a whole through calculation of the standardized incidence ratio (SIR). The excess relative risk per unit dose is also estimated (ERR/Gy). The risk values with 95% confidence intervals for all solid malignant neoplasms and cancers of respiratory organs and digestive system are estimated to be 0.91 (0.25; 1.57), 1.13 (-0.24; 2.40) and 0.85 (-0.3; 2.04), respectively.

URL: http://cyberleninka.ru/article/n/otsenka-radiatsionnyh-riskov-onkologicheskoy-zabolevaemosti-solidnymi-rakami-sredi-likvidatorov-posledstviy-chernobylskoy

 

 

 

The dependence of incidence rates of non-cancer thyroid diseases in the post-natal period at the Kaluga oblast children from term gestation, on which has taken place them in utero irradiation owing to technogenic iodine-131 incorporation

Title: The dependence of incidence rates of non-cancer thyroid diseases in the post-natal period at the Kaluga oblast children from term gestation, on which has taken place them in utero irradiation owing to technogenic iodine-131 incorporation

Author: Gorobets V.F

Reference: Radiation and Risk (Bulletin of the National Radiation and Epidemiological Registry) Year: 2011 Volume: 20 Issue: 1

Keywords: children, incidence of non-cancer thyroid diseases, irradiation in utero, technogenic iodine-131, cohort study

Abstract: The results of investigation of non-cancer thyroid diseases incidence rates, relative risks and etio-logic fractions by cohort study at 420 children from southwest region of the Kaluga oblast for the 12-year’s period after irradiation in utero on various terms of gestation at the expense of the technogenic iodine-131 incorporation are presented. Also 150 not exposed children as the control group was observed. It was established that incidence rates of thyroid diseases in the children irradiated in utero was at 2.6 times more than in the control group. The incidence of thyroid diseases among the children irradiated in utero was depended on the period of gestation at which irradiation was occurred. The highest level of the thyroid diseases incidence rate was in two subgroups of irradiated children: in the first subgroup every member was irradiated at the expense of iodine-131 from 4-th to 12-th week of gestation, in the second subgroup – from 16-th to 22-th week of gestation. It is known from radiobiological investigations that at these periods of gestation thyroid of foetus intensively accumulates radioactive iodine.

URL:http://cyberleninka.ru/article/n/zavisimost-urovney-zabolevaemosti-neonkologicheskimi-zabolevaniyami-schitovidnoy-zhelezy-v-postnatalnom-periode-u-detey-iz-kaluzhskoy

Comparative analysis of thyroid diseases incidence in prepubertal children of Kaluga oblast, exposed to iodine-131 in utero and resided in areas with different level of radioactive contamination after the Chernobyl accident

Title: Comparative analysis of thyroid diseases incidence in prepubertal children of Kaluga oblast, exposed to iodine-131 in utero and resided in areas with different level of radioactive contamination after the Chernobyl accident

Author: Gorobets V.F

Reference: Radiation and Risk (Bulletin of the National Radiation and Epidemiological Registry) Year: 2012 Volume: 21 Issue: 4

Keywords: children, in utero exposure to radiation, pollution of territories by iodine-131 and caesium-137, iodine supplementation, thyroid diseases incidence.

Abstract: Incidence of non-cancer thyroid diseases among prepubertal children exposed to radiation from Chernobyl in utero and resided in Zhizdra, Ulyanovo and Khvastovichi rayons of Kaluga oblast with different level of radioactive contamination was studied. It was shown that the rate of thyroid diseases incidence depended on natural iodine insufficiency in the areas of residence and radioiodine dose. The relative contribution of each of these factors can be estimated by difference between the incidence rate in exposed and unexposed children of the same age and the same area of residence.

URL:http://cyberleninka.ru/article/n/sravnitelnyy-analiz-zabolevaemosti-tireopatiyami-v-dopubertatnom-vozraste-detey-iz-kaluzhskoy-oblasti-obluchyonnyh-vnutriutrobno-za

Criteria for population protection and rehabilitation of the Russian territories long after the Chernobyl accident

Title: Criteria for population protection and rehabilitation of the Russian territories long after the Chernobyl accident

Author: Balonov M.I., Anisimova L.I., Perminova G.S.

Reference: Radiation and Risk (Bulletin of the National Radiation and Epidemiological Registry) Year: 1999 Issue: 11

Keywords: protection of the population, rehabilitation, Russia

Abstract: The paper outlines the history of development of criteria of radiation and social protection of the population of Russia living in the areas contaminated after the Chernobyl accident long after the accident. The trend for lowering the standards with time has been revealed and causes of this trend are analyzed. It is shown that the optimization principle has not been applied in an explicit form for protection of the population. The current and predicted radiation situation in the contaminated areas of Russia is described and the main pathways of internal and external exposure are identified. Possibilities available today to reduce population dose are discussed. Proposed are criteria and methods for population protection and rehabilitation of Russian territories.

URL:http://cyberleninka.ru/article/n/kriterii-zaschity-naseleniya-i-reabilitatsii-territoriy-rossii-v-otdalennyy-period-posle-chernobylskoy-avarii

Psychological status of emergency workers in the period long time after completion of emergency operations in the ChNPP zone

Title: Psychological status of liquidators in the period long time after completion of emergency operations in the ChNPP zone

Author: Matveeva N.P., Kaplan M.A., Belehov V.V.

Reference: Radiation and Risk (Bulletin of the National Radiation and Epidemiological Registry) Year: 1999 Issue: 11

Keywords: liquidators, psychological status

Abstract: Presented are results of investigation into the psychological status of 1986-1987 emergency workers (EWs) with somatic diseases in the period long after completion of emergency operations in the ChNPP zone. Comparative analysis is performed of the psychological status of EWs and persons not involved in emergency operations at ChNPP whose professional activity is connected with ionizing radiation. To estimate the psychological status of EWs the multifactor method of personal identification (MMPI) was used as well as Ch.D.Spielberger questionnaire for assessment of the personality level and reactive alert and the Lusherx27;s test.

URL:http://cyberleninka.ru/article/n/psihologicheskiy-status-likvidatorov-v-otdalennyy-period-posle-okonchaniya-rabot-v-zone-chaes

Technique (technology) of collection and analyses of individual data on thyroid cancer in the Unified Register of Russia and Belarus

Reference: Радиация и риск (Radiation and risk (Bulletin of the National Radiation and Epidemiological Registry)), 1999 Release Number: S2

Keywords: Russia, Belarus, register

Abstract: In the frame of this study problem about the introduction of a unified technology of collection and analysis of personalized information, in the State Register of Russia and Belarus, to establish the Unified Register of Russia and Belarus of thyroid cancer, for persons exposed to radiation as a result of the Chernobyl disaster, was solved.

The volume and quality of the information collected was determind.

Issues on cooperation between experts of the two countries and prospects of further development of the Single Registry was discussed and solved.

Study of possible radiation cancers after the accident at the Chernobyl nuclear power plant on the most contaminated territories of Ukraine

Title: Study of possible radiation cancers after the accident at the Chernobyl nuclear power plant on the most contaminated territories of Ukraine

Author: Prisyazhnyuk A.E., Grischenko V.G., Zakordonets V.A., Fuzik N.N., Slipenyuk E.M., Ryzhak I.N.

Reference: Radiatoin and Lisk 1995 No.6

Keywords: Zhitomir, Kiev

Abstract: Dynamic models of morbidity with malignant neoplasms on four most radiocontaminated territories of Zhitomir and Kiev oblasts of the Ukraine before and after the ChNPP accident were studied as well as indices of morbidity with tumours in the former Chernobyl district in the pre-accidental period were reconstructed. At the moment of the accident 274 thousand people among them 59200 children lived in five districts. In 1993, there were 152600 people including 25700 children in four districts (without Chernobyl one). It is found that for three categories of neoplasms – solid cancers, hemoblastoses and thyroid cancer – the frequency of the latter has been reliably increased (in particular in the children age group) what can be indicative of radiation effects.

URL: http://cyberleninka.ru/article/n/izuchenie-vozmozhnyh-radiatsionnyh-rakov-posle-avarii-na-chernobylskoy-aes-na-naibolee-zagryaznennyh-radionuklidami-territoriyah

 

 

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