タグ「Дети」
Author: V.V. Smirnov
Reference: Dissertation, candidate of medical sciences, St. Petersburg, 2006
Keywords: children, adolescence
Abstract: Aim of study – To study the dynamics of the state of the thyroid gland in residents of St. Petersburg exposed to ionizing radiation during childhood and adolescence as a result of the accident at the Chernobyl nuclear power plant.
Objectives of study: To study the dynamics of changes in the thyroid gland and the clinical signs of its functional status in patients exposed to ionizing radiation during childhood and adolescence as a result of the accident at the Chernobyl nuclear power plant. …
URL: http://www.dissercat.com/content/dinamika-sostoyaniya-shchitovidnoi-zhelezy-u-zhitelei-sankt-peterburga-podvergshikhsya-vozde
Author：Yu.Yu. Kozel
Reference: Dissertation, doctor of medical sciences, Roftov-na-Donu, 2006
Keywords: children, adolescence, immune-genetic research
Abstract: 20 years after the accident of the Chernobyl nuclear power plant, it becomes all the more clear, by facts, that sharp increase in the incidence of thyroid cancer, especially malignant tumors, has become the basic health effects of radiation. Most tragically, the above mentioned fact is observed among persons who, at the time of the accident, were children or teenagers and were exposed to radioactive iodine (Vtyurin BM et al., 2003). …
Aim of research: to develop tactics of examination of children and adolescents with thyroid tumors, based on the analysis of clinical and diagnostic data, including usage of immune-genetic studies. Optimization of method to treat these diseases, considering the immune-genetic characteristics of the child.
URL: http://www.dissercat.com/content/usovershenstvovanie-metodov-diagnostiki-i-lecheniya-opukholei-shchitovidnoi-zhelezy-u-detei-
Author: P.O. Rumyantsev
Reference: Dissertation, doctor of medical sciences, Obninsk, 2009
Keywords: children, adolescence, histological verification, English researchers, Thomas GA & Williams E.D.
Abstract: … Since 1992 to the present time, in the contaminated territories of the Russian Federation, following the accident at the Chernobyl nuclear power plant, were detected an abnormally high incidence of thyroid cancer in the cohort of individuals exposed in childhood and adolescence [BM Vtyurip et al, 2001]. In the late ’90s, for a review, a histogram-preparation of all previously diagnosed cases of thyroid cancer was available for an independent examination by the international panel of pathologists, chaired by Professor Williams (UK). As result of the independent histological verification, in many cases the diagnosis of thyroid cancer was not confirmed, in some cases histological type was changed, or histopathological version of the thyroid carcinoma was elaborated. Since 1999 histo-preparation of all newly diagnosed cases of thyroid cancer in children and adolescents, (at the time of diagnosis or at the time of the Chernobyl accident) born after 1967, has undergone regular independent histological verification as part of international projects of bank of tissue, blood and nucleic acids, whose headquarter is situated in London [Thomas GA & Williams E.D., 2001]. After more than twenty years after the Chernobyl accident, there is no information on the exact number of cases of thyroid cancer (based on the results of the international histological verification) reported of children and adolescents in the contaminated territories of the Russian Federation in the post-Chernobyl period ….
URL: http://www.dissercat.com/content/kompleksnaya-diagnostika-i-lechenie-raka-shchitovidnoi-zhelezy-na-sonove-etiopatogenetichesk
Author: S.V. Osipov
Reference: Dissertation, candidate of medical sciences, Ufa, 2005
Keywords: surgical treatment, remote long-term consequences, survival rate
Abstract: Scientific novelty of the work:
1. For the first time an analysis of the clinical course and remote results of surgical treatment of thyroid cancer, in children and adolescents in the region of the Southern Urals, (Chelyabinsk region) in terms up to 25 years, is shown.
2. The clinical course of thyroid cancer in children and adolescents is defined by the presence symptom complex – a painless lump in the neck, an increase in cervical lymph nodes under the guise of “banal” adenopathy with a predominance of well-differentiated thyroid carcinomas.
3. Conserving surgical treatment of differentiated thyroid cancers, in children and adolescents, is to provide excellent immediate long-term results.
4. The cumulative survival rate after surgical treatment of highly differentiated form of thyroid cancer, in children and adolescents in terms of supervision of up to 25 years, – 94.0%.
URL: http://www.dissercat.com/content/klinicheskoe-techenie-i-otdalennye-rezultaty-khirurgicheskogo-lecheniya-raka-shchitovidnoi–0
Author: A.V. Rozhko
Reference: Dissertation, 2011
Keywords: medical treatment, reliable methods, epidemiology
Abstract: The assessment, obtained by the above mentioned methods, to determine quantities of excessive risk, depending on the dose of the thyroid gland, is not considered to be reliable. The most accurate is to be the one based on analytical cohort, whose number is limited (UNSCEAR 2000). Therefore, it requires further well-designed epidemiological studies of radiation, in which the values of 1. individual doses to members of the cohort and 2. a comparison to an adequate control group of unexposed persons are considered …
URL: http://www.dissercat.com/content/chernobylskaya-katastrofa-mediko-biologicheskie-zakonomernosti-formirovaniya-i-prognozirovan
Author: D.E. Shilin
Reference: Dissertation, 2002
Keywords: perinatal stage, iodine deficiency
Abstract: The urgency of the problem. The diverse thyroid pathology has a leading position in the structure of endocrine diseases in humans, beginning to form already in childhood and adolescence. Diseases of thyroid gland (TG) are distributed especially in regions with iodine deficiency in the biosphere. Endemic goiter and other health disorders, related to iodine deficiency, present severe medical and social problem, which has been intensively studied in the last decade in Russia and abroad. New indicators and criteria of severity of the disease (WHO, 1994) are developed and effectively used, along with the recommendations of physiological needs of micronutrients (WHO, 1996). Negative impact on the child’s body with deficiency of thyroid hormones caused by even a slight decrease in the supply of iodine, is proven, especially in the perinatal stage of development.
URL: http://leb.nlr.ru/edoc/58274/
Author: A.Yu. Abrosimov
Reference: Dissertation, 2004
Keywords: increased number on incidence, comparison, pre-accidental period, post-accidental period
Abstract: The accident at the Chernobyl Nuclear Power Plant (CNPP) April 26, 1986 turned out to be a disaster with psychological, social and health consequences for a large number of people. Release of significant quantities of radionuclide iodine led millions of people in Belarus, Russia and Ukraine to radiation exposure of the thyroid gland (TG). After a few years, thyroid cancer (TC) became reality, which is still existent at present.
Before Chernobyl, in all countries thyroid cancer among children had been considered a rare disease. In Belarus, within the pre-accident period of 15 years, thyroid cancer was diagnosed in 8 children, 21 adolescents, aged 15 to 18 years, and 1,465 patients aged 19 years and older. Over the 15-year period after the accident (1986-2000), thyroid cancer was diagnosed in 703 children, 267 adolescents and 6719 adults. From 1990 to 2000 it was diagnosed in 674 children, 262 adolescents and 564 young adults who, at the time of the accident, were from 0 to 18 years old (Demidchik EP et al., 2002). After the accident, the incidence of thyroid cancer increased, compared to the pre-accident period, in children 88.5 times, in adolescents – 11.8 times, in adults – 4.6 times. In Ukraine, within the 5-years pre-accident period (1981-1985), there were 25 cases of thyroid cancer in children, whereas in the subsequent 5-years period (1986-1990.) – 61 cases, and in the next 5 years (1991 – 1995). -220 cases (Tronko ND et al., 2002). The incidence of thyroid cancer in children of Ukraine, in 1986-1990 increased 2.2 times, in 1991-1995 – 8 times, and in 1996-2000 – 8.2 times.
URL: http://www.referun.com/n/rak-schitovidnoy-zhelezy-u-detey-i-podrostkov-rossii-posle-avarii-na-chernobylskoy-aes
