Assessing the impact of methods of preoperative and intraoperative differential diagnosis on the surgical treatment of thyroid cancer
Author: P.A. Pankova
Reference: Dissertation, candidate of medical sciences, St. Petersburg, 2008
Keywords: differential diagnosis, reduce risk, cytological and histological studies
Abstract: Object of resarch: To determine the relevance and adequacy of pre-operative methods in the differential diagnosis of thyroid nodules in order to detect cancer of the thyroid gland; To compare methods of urgent cytological and histological studies of thyroid nodules; To substantiate the necessity of intraoperative, cytologic research of the regional lymph nodes in the neck, for the detection of metastases of thyroid cancer; To develop algorithm of intraoperative diagnosis of thyroid nodules.
Scientific novelties: The paper shows limited role:
– preoperative examination methods in the differential diagnosis of thyroid nodules in order to detect cancer of the thyroid gland.
– The study by modern evidence-based medicine has shown that any formation of thyroid may be a carcinoma, regardless of its palpable characteristics, size, hormonal activity or ultrasound picture.
It is proven that the combined use of fixed-term cytological and histological studies significantly improves intraoperative differential diagnosis of differentiated thyroid cancer and reduces the risk of performance of inadequate surgical intervention.