De novo ceramide synthesis is responsible for the anti-tumor properties of camptothecin and doxorubicin in follicular thyroid carcinoma
Author: Rath, Geraldine / Schneider, Christophe / Langlois, Benoit / Sartelet, Hervé / Morjani, Hamid / Btaouri, Hassan E.L. / Dedieu, Stephane / Martiny, Laurent
Reference: The International Journal of Biochemistry & Cell Biology, 41 (5), p.1165-1172, May 2009
doi: 10.1016/j.biocel.2008.10.021
Keywords: Ceramide; Apoptosis; Thyroid; Cancer; Doxorubicin; Camptothecin
Abstract: …treatment. Follicular thyroid carcinomas were cultured for…control). 1 Introduction Thyroid malignant diseases represent…1995 ). After the Chernobyl tragedy in April 1986, the incidence rate of thyroid cancers rose more than…well-differentiated form of thyroid cancer, accounts for up to…
URL: http://www.sciencedirect.com/science/article/pii/S1357272508004433