タグ「Histology」
Author: Y. Iwata, K. Suzuki, T. Wakuda et al.
Reference: PLoS ONE. — 2008. — Vol. 3, № 5. — P. e2283.
Keywords: subgranular zone, immunohistochemistry, NMDA, subventicular zone
Abstract: Epidemiological studies suggest that radiation exposure may be a potential risk factor for schizophrenia in adult humans. Here, we investigated whether adult irradiation in rats caused behavioral abnormalities relevant to schizophrenia.
A total dose of 15-Gy irradiation in six fractionations during 3 weeks was exposed to the forebrain including the subventricular zone (SVZ) and subgranular zone (SGZ) with male rats in the prone position. Behavioral, immunohistochemical, and neurochemical studies were performed three months after fractionated ionizing irradiation. Three months after fractionated ionizing irradiation, the total numbers of BrdU-positive cells in both the SVZ and SGZ zones of irradiated rats were significantly lower than those of control (sham-irradiated) rats. Hyperactivity after administration of the dopaminergic agonist methamphetamine, but not the N-methyl-D-aspartate (NMDA) receptor antagonist dizocilpine, was significantly enhanced in the irradiated rats although spontaneous locomotion in the irradiated rats was significantly lower than that of controls. Behavioral abnormalities including auditory sensory gating deficits, social interaction deficits, and working memory deficits were observed in the irradiated rats.
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386242/?tool=pubmed
Title: Histological changes in Pinus sylvestris L. in the proximal-zone around the Chernobyl power plant
Author: Lavrans Skuterud, Natalia I. Goltsova, Roger Næumann, Torbjørn Sikkeland, Tore Lindmo
Reference: Science of The Total Environment, Volume 157, 11 December 1994, Pages 387-397
DOI:http://dx.doi.org/10.1016/0048-9697(94)90602-5
Keywords: Histology; Pine trees; Radiation doses; Effects; Radioactivity; Chernobyl
Abstract: In September 1990, samples of wood and bark were collected from Pinus sylvestris L. at three locations exposed to different levels of radioactive fallout from the 1986 accident at the Chernobyl nuclear power plant (NPP). Cross-sections of wood from the most exposed location showed a distinct change in histology in the annual ring of 1986, a consequence of the accident on 26 April. The width of annual rings decreased after the accident, and the relative width of latewood in annual rings increased transiently in 1986 and subsequently decreased in 1987. In 1987, an increase in the number of vertical resin ducts was observed, related to contamination at the location, and the number of radial rays decreased at the two locations of higher contamination. The radionuclide content in the bark was found to correlate with the degree of damage in the wood. There are several hypotheses about the contribution from various types
of radioactive contamination, but the results indicate that both ‘cloud γ’ and deposited radioactivity (β and γ) were of importance. The present work suggests that detailed studies of dose-effect relationships after exposure to different dose rates and radiation qualities may establish the usefulness of pine trees as in situ, time-recording differential dosimeters of ionizing radiation.
URL: http://www.sciencedirect.com/science/article/pii/0048969794906025
Title: Histological characterization of papillary thyroid carcinoma in children, adolescents and young adults in Russia after the Chernobyl accident
Author: Lushnikov, Eugeny F / Abrossimov, Alexandre Yu
Reference: International Congress Series, 1234, p.239-244, May 2002
doi: 10.1016/S0531-5131(01)00613-6
Keywords: Chernobyl; Thyroid carcinoma; Histology
Abstract: The purpose of the study was to analyze the histological features of post-Chernobyl papillary thyroid carcinoma (PTC) that occurred in children, adolescents and young adults living in radionuclide-contaminated territories of the Russian Federation. We reviewed the histological sections of thyroid carcinoma in 123 patients (39 males and 84 females) aged 0–16 years at the time of accident from Bryansk, Kaluga, Oriol and Tula regions of Russia….
URL:http://www.sciencedirect.com/science/article/pii/S0531513101006136
