Micronucleus frequency in Gomel (Belarus) children affected and not affected by thyroid cancer

Title: Micronucleus frequency in Gomel (Belarus) children affected and not affected by thyroid cancer
Author: Zotti-Martelli, Laura / Migliore, Lucia / Panasiuk, Galina / Barale, Roberto

Reference: Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 440 (1), p.35-43, Mar 1999

doi: 10.1016/S1383-5718(99)00012-1

Keywords: Human lymphocyte micronucleus assay; Thyroid cancer; Chernobyl accident; Ionizing radiation

Abstract: Cytogenetic monitoring was carried out on a group of children from Gomel (Belarus), one of the areas most severely affected by radioactive contamination following the accident at the Chernobyl nuclear power plant, in 1986. We performed the micronucleus test (MN) in binucleated lymphocytes of 42 children (mean age: 11±2.34 years), 16 of whom were affected by thyroid gland tumor. Thirty healthy children living in Pisa (mean age: 14.96±2.17 years) were enrolled in the study as controls….

URL: http://www.sciencedirect.com/science/article/pii/S1383571899000121