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Radioecological evaluation of protective activities applied in agricultural sphere in Belarus between 2000 and 2005. (to the 20th anniversary of the Chernobyl disaster)

Title: Radioecological evaluation of protective activities applied in agricultural sphere in Belarus between 2000 and 2005. (to the 20th anniversary of the Chernobyl disaster)

Author: Podolyak A.G., Bogdevich I.M., Ageets V.Yu., Timofeev S.F.

Reference: Radiation Biology, Radioecology, (Russian:“РАДИАЦИОННАЯ БИОЛОГИЯ. РАДИОЭКОЛОГИЯ “), Volume 47, Issue 3, 2007, Pages 356-370

ISSN: 0869-8031

 DOI: 10.1134/S0869803107030162

Keywords: Belarus, protective activities in agriculture, 137Cs , 90Sr, 2000~2005

Abstract: Gives basic evaluation of protective activities, in agriculture, in the land contaminated by the Chernobyl accident. Analysis of the principles of the activities of 90sr and 137cs. Evaluation of liquidation of the disaster.

URL: http://elibrary.ru/item.asp?id=9516611

Genetic consequences of irradiation in scots pine Pinus sylvestris L. population

Title:  Genetic consequences of irradiation in scots pine Pinus sylvestris L. population

Author: Oficerov M.V., Igonina E.V.

Reference: Genetics, (Russian: “ГЕНЕТИКА”) 2009 Feb; 45(2):209-14.

ISSN: 1022-7954

DOI: 10.1134/S1022795409020082

Keywords: Scots pine, contamination, genetics

Abstract: The genetic consequences of irradiation were studied in a Scots pine population from a region contaminated as a result of the Chernobyl meltdown. Mutations of isozyme loci were not detected in seeds collected from trees of the first post-meltdown generation in 2004. The frequency of cells with chromosome aberrations in the root meristem of seedlings grown from the seeds did not differ from the control level. A deviation from the expected ratio 1:1 was observed for some isozyme alleles in endosperms of seeds obtained from heterozygous trees.

URL: http://www.ncbi.nlm.nih.gov/pubmed/19334615

The development of differentiation programs for the prevention and rehabilitation of children with diseases of the thyroid gland, including those living in the contaminated areas with radionuclides

Author: L.V. Shiryaeva

Reference: Dissertation, candidate of medical sciences, Moscow, 2006

Keywords: iodine deficiency, ioduria

Abstract: Radiation damage to the thyroid gland is one of the most serious consequences of the Chernobyl accident. Today, growth of thyroid cancer in people who were exposed in childhood [93, 9.4], is convincingly proven. On dose dependence of risk of developing thyroid cancer, also discussion on issues on increase of benign thyroid pathology …

Aim of research: To develop and demonstrate the effectiveness of program of preventing iodine deficiency and rehabilitation from iodine deficiency disorders, based on studis of thyroid status, ioduria and other microelementosis in children, including those living in “contaminated” areas with radionuclides due to the Chernobyl accident.
URL: http://www.dissercat.com/content/razrabotka-differentsirovannykh-programm-profilaktiki-i-reabilitatsii-detei-s-zabolevaniyami

Dynamics of state of thyroid gland in the residents of St. Petersburg exposed to ionizing radiation during their childhood and adolescence as result of the accident at the Chernobyl nuclear power plant

Author: V.V. Smirnov

Reference: Dissertation, candidate of medical sciences, St. Petersburg, 2006

Keywords: children, adolescence

Abstract: Aim of study – To study the dynamics of the state of the thyroid gland in residents of St. Petersburg exposed to ionizing radiation during childhood and adolescence as a result of the accident at the Chernobyl nuclear power plant.

Objectives of study: To study the dynamics of changes in the thyroid gland and the clinical signs of its functional status in patients exposed to ionizing radiation during childhood and adolescence as a result of the accident at the Chernobyl nuclear power plant. …

URL: http://www.dissercat.com/content/dinamika-sostoyaniya-shchitovidnoi-zhelezy-u-zhitelei-sankt-peterburga-podvergshikhsya-vozde

Thyroid gland: age-concerned features of the structure, and latent pathology

 

Author: T.S. Mukhina

Reference: Dissertation, candidate of medical sciences, Volgograd, 2008

Keywords: age dependence, morphology, structural features

Abstract: Increased incidence of thyroid cancer in many regions of Russia determines the relevance of the study of regional structural features of the body and the clinicopathologic features of benign and malignant tumors, of which differential diagnosis in preoperative stage can be extremely difficult (Romanchishen AF, 1992; Paches AI, Propp PM, 1995; Khmelnitsky OK, 2002). Especially, interest in the problems of thyroidology increased in the period after the accident at the Chernobyl nuclear power plant. Urgent study of radiogenic thyroid cancer became highly actual, for which the position remains still controversial (Lushnikov EF Tsib AF, Yamashita, S., 2006). …

The purpose of the study: To determine 1.the structural features of the thyroid gland in the mature, older and old age and 2. morphological features of latent disease, on the basis of complex morphological and morphometric research.

URL: http://www.dissercat.com/content/vozrastnye-osobennosti-stroeniya-i-latentnaya-patologiya-shchitovidnoi-zhelezy

 

Improvement of methods of diagnosis and treatment of thyroid tumors in children and adolescents (on the model of the Rostov region).

Author:Yu.Yu. Kozel

Reference: Dissertation, doctor of medical sciences, Roftov-na-Donu, 2006

Keywords: children, adolescence, immune-genetic research

Abstract: 20 years after the accident of the Chernobyl nuclear power plant, it becomes all the more clear, by facts, that sharp increase in the incidence of thyroid cancer, especially malignant tumors, has become the basic health effects of radiation. Most tragically, the above mentioned fact is observed among persons who, at the time of the accident, were children or teenagers and were exposed to radioactive iodine (Vtyurin BM et al., 2003). …

Aim of research: to develop tactics of examination of children and adolescents with thyroid tumors, based on the analysis of clinical and diagnostic data, including usage of immune-genetic studies. Optimization of method to treat these diseases, considering the immune-genetic characteristics of the child.

URL: http://www.dissercat.com/content/usovershenstvovanie-metodov-diagnostiki-i-lecheniya-opukholei-shchitovidnoi-zhelezy-u-detei-

Pathomorphological and immunohistochemical study of thyroid tumors in children in ecological situations of Kuzbass

 

Author: N.E. Verzhbitskaya

Reference: Dissertation, candidate of medical sciences, Novosibirsk, 2006

Keywords: children, ecological background,

Abstract: Currently, thyroid cancer in children due to the unfavorable ecological situation, the consequences of the Chernobyl nuclear power plant in the Tomsk region, the tests at the Semipalatinsk test site, has grown considerably in number. O.K. Khmelnitsky et al. (2000) states on the etiology of thyroid disease: “Not even one discipline of endocrine pathology is related to the environment as closely as to thyroid disease, because the structure and function of the thyroid gland is closely associated with the receipt of iodine and other trace elements from putside. In this regard, thyroid disease can be rightfully considered as a marker of ecological trouble. ” In the group of children and adolescents, thyroid cancer is the most common tumor of the endocrine system. This disease, which occurs much less frequently than in adults, amounts, however, up to 8-15% of malignant solid tumors of the head and neck in children. …

The purpose of the study : To study the structure and pathomorphological features of thyroid cancer in children in Kuzbass and, on this basis, to develop the complex of measures of organization of cancer monitoring, and to improve the results of the differential diagnosis of benign thyroid nodules and thyroid cancer in children.

URL: http://www.dissercat.com/content/patomorfologicheskoe-i-immunogistokhimicheskoe-issledovanie-opukholei-shchitovidnoi-zhelezy-

Efficiency of radio-iodine-therapy for patients suffering from thyroid cancer with metastases to the lungs and mediastinum

Author: N.V. Podolkhova

Reference: Dissertation, candidate of medical sciences, Obninsk, 2007

Keywords: oncologic disease

Abstract: For people affected by the accident of the Chernobyl nuclear power plant, living in areas where there were no large-scale dosimetry studies, link of the growth of cancer of the thyroid gland to radiation must be set by the presence of characteristic features described by ourselves: Increase of incidence among children and adults after the completion of the minimum latency (~ 5-6 years), aggression of tendency of childhood cancers, the lack of growth in oncologic diseases of thyroid in children born after the collapse of iodine radionuclides (1987 and later) …

URL: http://www.dissercat.com/content/effektivnost-radioidoterapii-u-bolnykh-rakom-shchitovidnoi-zhelezy-s-metastazami-v-legkie-i-

Comprehensive diagnosis and treatment of thyroid cancer based on etiopathogenetic and prognostic factors

 Author: P.O. Rumyantsev

Reference: Dissertation, doctor of medical sciences, Obninsk, 2009

Keywords: children, adolescence, histological verification, English researchers, Thomas GA & Williams E.D.

Abstract: … Since 1992 to the present time, in the contaminated territories of the Russian Federation, following the accident at the Chernobyl nuclear power plant, were detected an abnormally high incidence of thyroid cancer in the cohort of individuals exposed in childhood and adolescence [BM Vtyurip et al, 2001]. In the late ’90s, for a review, a histogram-preparation of all previously diagnosed cases of thyroid cancer was available for an independent examination by the international panel of pathologists, chaired by Professor Williams (UK). As result of the independent histological verification, in many cases the diagnosis of thyroid cancer was not confirmed, in some cases histological type was changed, or histopathological version of the thyroid carcinoma was elaborated. Since 1999 histo-preparation of all newly diagnosed cases of thyroid cancer in children and adolescents, (at the time of diagnosis or at the time of the Chernobyl accident) born after 1967, has undergone regular independent histological verification as part of international projects of bank of tissue, blood and nucleic acids, whose headquarter is situated in London [Thomas GA & Williams E.D., 2001]. After more than twenty years after the Chernobyl accident, there is no information on the exact number of cases of thyroid cancer (based on the results of the international histological verification) reported of children and adolescents in the contaminated territories of the Russian Federation in the post-Chernobyl period ….

URL: http://www.dissercat.com/content/kompleksnaya-diagnostika-i-lechenie-raka-shchitovidnoi-zhelezy-na-sonove-etiopatogenetichesk

Determination of the frequency of mutant cells on loci of glycophorin A and T- of cell receptor: to form (determine) group of risk in relationship with development of thyroid cancer

Author: A.O.Vereshagina

Reference: Dissertation, candidate of biology, Obninsk, 2006

Keywords: reevaluation of the relationship between radiation exposure and thyroid cancer, GPA-and-TCR-test, formation of groups of risk

Abstract: … the aim of this work was to elucidate a few questions.

  1. People living in the contaminated areas, suffering from thyroid cancer: Do patients actually have elevated frequency of cells with gene mutations?
  2. Does utilization of GPA-and TCR-test promise the formation of groups of risk for the occurrence of thyroid cancer? Informative evaluation of these tests for dosimetry at different doses to the thyroid gland is also of our interests.

To achieve these objectives, we were supposed to solve the following problems: 1) A comparative study of the frequency of occurrence of mutant cells by TCR-and GPA-loci among 1. residents affected by the Chernobyl disaster areas 2. people unexposed yet being under examination; 2) To determine whether there is a relationship between the dose absorbed by the thyroid and the frequency of mutant cells by GPA-and TCR-loci, among affected residents, as a result of the accident at the Chernobyl nuclear power plant (taking example of residents in Orel region) 3) a comparative study of the frequency of mutant cells, among residents in the Orel region 1. with benign nodular pathology on thyroid gland and 2. without it; 4) a comparative study of the frequency of mutant cells on 2 specified loci in 1. thyroid cancer patients before treatment and 2. healthy individuals; 5) to evaluate the possibility of using these tests for the formation of groups of risk, for the occurrence of thyroid cancer; …

URL: http://www.dissercat.com/content/opredelenie-chastoty-mutantnykh-kletok-po-lokusam-glikoforina-i-t-kletochnogo-retseptora-s-t

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