Author: I.A. Pavlov
Reference: Dissertation, candidate of medical sciences, Rostov-na-Donu, 2010
Keywords: papillary carcinoma of thyroid gland, endogenous factor, exogenous factor
Abstract: It is shown that a significant role in the development of thyroid disorders, including thyroid cancer, are played by both endogenous and exogenous factors. Among the latter, a special place is occupied by the influence of radiation, in particular the consequences of the accident of the Chernobyl nuclear power plant (JI.A Ilyin et al. 1989; Abrosimov Yu et al., 2001; Kravtsov VJ et al., 2009; Troshin B. P., Tikhonov, Y., 2009), and shown in our work (Pavlova TV, et al., 2000, 2001, 2002, 2007). In addition, specific attention is drawn to other factors (Khmelnytsky OK, AV Kiselev, 1998) like iodine deficiency states (PABSEC Volokh Yu VP, Van – Mildsvort JI., 1992), a number of unhealthy habits etc …
URL: http://www.dissercat.com/content/kliniko-morfologicheskie-diagnosticheskie-kriterii-papillyarnogo-raka-shchitovidnoi-zhelezy-
Author: S.V. Osipov
Reference: Dissertation, candidate of medical sciences, Ufa, 2005
Keywords: surgical treatment, remote long-term consequences, survival rate
Abstract: Scientific novelty of the work:
1. For the first time an analysis of the clinical course and remote results of surgical treatment of thyroid cancer, in children and adolescents in the region of the Southern Urals, (Chelyabinsk region) in terms up to 25 years, is shown.
2. The clinical course of thyroid cancer in children and adolescents is defined by the presence symptom complex – a painless lump in the neck, an increase in cervical lymph nodes under the guise of “banal” adenopathy with a predominance of well-differentiated thyroid carcinomas.
3. Conserving surgical treatment of differentiated thyroid cancers, in children and adolescents, is to provide excellent immediate long-term results.
4. The cumulative survival rate after surgical treatment of highly differentiated form of thyroid cancer, in children and adolescents in terms of supervision of up to 25 years, – 94.0%.
URL: http://www.dissercat.com/content/klinicheskoe-techenie-i-otdalennye-rezultaty-khirurgicheskogo-lecheniya-raka-shchitovidnoi–0
Author: A.S. Butorin
Reference: Dissertation, candidate of medical sciences, Ufa, 2006
Keywords: surgical approach, long-term effects
Abstract: The urgency of this problem in our country increased after the Chernobyl accident in 1986, due to the sharp increase in the frequency of thyroid cancer in the “contaminated” areas of Belarus (Demidchnk E, F, “2003), Ukraine (Komissarenko And B., 2003. 2004 ) and Russia (Polyakov-H., et al,. 1998; Zvonov IA et. al., 1993). The cases of multiple organ of cancer of the thyroid gland, according to the literature, are – from 4.7% up to 87.5%. So far, there are no uniform opinion neither to the incidence of multifocused thyroid cancer, nor any features of its clinical course. Surgical approach remains controversial. …
The purpose of the present study has been to investigate the clinical course and long-term, remote results of surgical treatment of multifocused thyroid cancer, as well as the development of the optimal surgical approach.
URL: http://www.dissercat.com/content/klinicheskoe-techenie-i-otdalennye-rezultaty-khirurgicheskogo-lecheniya-mnogofokusnogo-raka-
Author: P.A. Pankova
Reference: Dissertation, candidate of medical sciences, St. Petersburg, 2008
Keywords: differential diagnosis, reduce risk, cytological and histological studies
Abstract: Object of resarch: To determine the relevance and adequacy of pre-operative methods in the differential diagnosis of thyroid nodules in order to detect cancer of the thyroid gland; To compare methods of urgent cytological and histological studies of thyroid nodules; To substantiate the necessity of intraoperative, cytologic research of the regional lymph nodes in the neck, for the detection of metastases of thyroid cancer; To develop algorithm of intraoperative diagnosis of thyroid nodules.
Scientific novelties: The paper shows limited role:
– preoperative examination methods in the differential diagnosis of thyroid nodules in order to detect cancer of the thyroid gland.
– The study by modern evidence-based medicine has shown that any formation of thyroid may be a carcinoma, regardless of its palpable characteristics, size, hormonal activity or ultrasound picture.
It is proven that the combined use of fixed-term cytological and histological studies significantly improves intraoperative differential diagnosis of differentiated thyroid cancer and reduces the risk of performance of inadequate surgical intervention.
URL: http://www.dissercat.com/content/otsenka-vliyaniya-na-khirurgicheskuyu-taktiku-lecheniya-raka-shchitovidnoi-zhelezy-metodov-d
Author: S.V. Korenev
Reference: Dissertation, doctor of medical sciences, Obninsk, 2005
Keywords: adult population, therapeutic and diagnostic tactics
Abstract: Based on the comprehensive clinical and epidemiological research and generalization of experience of work carried out in the post-Chernobyl period in the Bryansk region, an optimal therapeutic and diagnostic tactics in patients with thyroid cancer in a population of adults living on-contaminated areas is developed. The work is the first of comprehensive works, dedicated to the study of complex problems of thyroid cancer in the adult population living in the contaminated areas. …
URL: http://www.dissercat.com/content/rak-shchitovidnoi-zhelezy-u-vzroslogo-naseleniya-prozhivayushchego-na-zagryaznennykh-radionu
Author: L.B. Drygina
Reference: Dissertation, 2002
Keywords: liquidators
Abstract: Development of clinical and laboratory criteria to evaluate the adaptive-regulatory system in liquidators of Chernobyl accident, in remote period, for the solutions of diagnostic, prognostic problems. To these days, medical care to the liquidators of the of the Chernobyl accident (LPA) remains one of the national objectives (Nikiforov, AM, 1996; Tsib AF, 1998; Lushnikov. F. et al, 1999). The total number of liquidators in Russia is more than 300 thousand people. According to the Russian State Medical Dosimetry Registry (RSMDR), epidemiologically significant increase in classes of disease such as cardiovascular system, digestive system, endocrine system, diseases of musculoskeletal system and connective tissue (Shantyr II and others, 1996) are registered in the liquidators. In remote periods after the Chernobyl accident, risk of destructive autoimmune processes (Estinbeeva MJ, 994) and solid neoplasms (Ivanov VK et al, 1999) may increase …
URL: http://www.dissercat.com/content/kliniko-laboratornye-kriterii-otsenki-sostoyaniya-adaptatsionno-regulyatornykh-sistem-u-likv
Author: N.O. Omapaskhabov
Reference: Dissertation, 2007
Keywords: demography, somatic abnormalities, digestive system
Abstract: For the first time, a comprehensive comparative evaluation is carried out of the dynamics of demographic indicators, indicators of the overall level and structure of newly diagnosed disease, as well as cytogenetic indices in child population living for 20 years in the contaminated areas following the accident of the Chernobyl nuclear power plant. Implements, in the initial -“iodine”- period of the Chernobyl accident, direct measurements of absorbed doses of the thyroid gland (TG) in children of Zhizdra area, allowing, for the first time, to evaluate the observed functional changes in the thyroid depending on the individual doses of incorporated radionuclides of iodine. Determines the role of cytogenetic damage in the development of somatic abnormalities in children with elevated levels of chromosomal aberrations. Especially in prenatally irradiated cases, morphological and functional changes in the thyroid gland diseases in the respiratory and digestive system, are more often encountered. The results obtained in general: Materials of the research formed the basis for the planning of socio-economic measures and medical administration of the Kaluga region in the contaminated areas after the Chernobyl accident …
URL: http://www.dslib.net/radio-bio/sravnitelnaja-ocenka-pokazatelej-obwego-urovnja-i-struktury-zabolevaemosti-s.html
Author: A.R. Islamova
Reference: Dissertation, 2004
Keywords: men, women, different characteristics, health conditions
Abstract: The accident at the Chernobyl nuclear power plant, is unprecedented in scale of disaster, which resulted in succession of combined effects of a number of pathogenic factors to a huge population of people, which, in the first place, is attributed to ionizing radiation. Thus one of the major social object is to monitor the demographic-medical situation in individual populations. The most exposed and one of the largest categories of the population affected by the Chernobyl accident are the so-called “liquidators”. Majority of liquidators are men. At the same time, about 6,000 women who took part in liquidation of the Chernobyl accident are registered in the Russian State Medical Dosimetry Registry (RSMDR). These women are group of people with certain conditions and doses of external and internal exposure, initial state of health and other characteristics that are different from those of the male population of the liquidators and require further study and analysis.
URL: http://www.dissercat.com/content/zabolevaemost-zlokachestvennymi-novoobrazovaniyami-uchastnits-likvidatsii-posledstvii-avarii
Author:N.V. Bolotova
Reference: Dissertation, 1995
Keywords: endemic goiter, micronutrient metabolism
Abstract: To study the clinical course and to develop methods to predict the developmen of endemic goiter in children, on the basis of a comprehensive assessment of micronutrient metabolism and functional activity of the thyroid ‘gland –
URL: http://medical-diss.com/medicina/endemicheskiy-zob-u-detey
Author: A.V. Rozhko
Reference: Dissertation, 2011
Keywords: medical treatment, reliable methods, epidemiology
Abstract: The assessment, obtained by the above mentioned methods, to determine quantities of excessive risk, depending on the dose of the thyroid gland, is not considered to be reliable. The most accurate is to be the one based on analytical cohort, whose number is limited (UNSCEAR 2000). Therefore, it requires further well-designed epidemiological studies of radiation, in which the values of 1. individual doses to members of the cohort and 2. a comparison to an adequate control group of unexposed persons are considered …
URL: http://www.dissercat.com/content/chernobylskaya-katastrofa-mediko-biologicheskie-zakonomernosti-formirovaniya-i-prognozirovan
