Title: Cytogenetic study in lymphocytes from children exposed to ionizing radiation after the Chernobyl accident
Author: L. Padovani, D. Caporossi, B. Tedeschi, P. Vernole, B. Nicoletti, F. Mauro
Reference: Mutation Research/Genetic Toxicology, Volume 319, Issue 1, September 1993, Pages 55–60
DOI: http://dx.doi.org/10.1016/0165-1218(93)90030-H
Keywords: Chernobyl; Chromosome aberrations; Biological dosimetry
Abstract: The present study concerns the monitoring of children from the Byelorussian, Ukrainian and Russian republics exposed to the fall-out of the Chernobyl accident. Cytogenetic analyses have been performed on 41 children coming from different areas and exhibiting varying amounts of 137Cs internal contamination, as evaluated by whole-body counter (WBC) analysis. On a total of 28670 metaphases scored, radiation-induced chromosome damage is still present, although at a very low frequency. Due to the very low fraction of dicentrics, because of the time elapsed from the accident and the relatively low doses of exposure, radiobiological dosimetry is not possible for these children. However, considering that the WBC data indicate that the children are still exposed to 137Cs contamination, the observed occurrence of stable chromosome rearrangements and breaks may represent the persisting effect of continuous low doses of radiation. The present study also indicates that the parallel use of internal contamination dosimetry and cytogenetics could be usefully employed to monitor individual exposure to radiation and to define further management measures.
ＵＲＬ：http://www.sciencedirect.com/science/article/pii/016512189390030H
Author: Gotlib V.Ya, Serebryanyi A.M., Kudryashova O.V., Pelevina I.I. et al.
Reference: Радиационная биология. Радиоэкология (Radiation Biology. Radioecology) Year of publication: 2001
Keywords: children, lymphocyte, radiation-induced diseases
Abstract: By implementing micronucleus test, we studied the spontaneous level of damaged lymphocytes in groups of children under different conditions of life and different environmental stress and its variation when exposed to radiation in vitro. It is shown that higher the level of spontaneous damaged lymphocytes, higher is the radiosensitivity. The correlation therebetween is studied.
URL: http://www.fesmu.ru/elib/Article.aspx?id=65930
Author: DE Shilin
Reference: Journal Tyyronet 2000 number 3 ”
Keywords: pediatrics
Abstract: The aim of the study is a retrospective analysis of data obtained in 1992 to 1997 from the Russian fragment of the international projects “Thyroid Gland: a standarized analysis of iodine sufficiency in Europe” and “Children of Chernobyl” and in observation of school children in Moscow. Object of research included children living in territories contaminated with radionuclides due to the Chernobyl accident, where iodine insufficiency of different levels was detected.
URL: http://www.thyronet.ru/spetsialistam/zhurnal/archiv/2000g/3/K_voprosu_o_vnedrenii_mejdunarodnyh_normativov_ultrazvukovogo_obema_schitovidnoi_jelezy_v_pediatricheskuyu_praktiku.html?page=0
Author: Editors: G. Hennemann, E.P. Krenning
Reference: Journal Тиронет (Thyronet), 2001, No. 2 THYROID INTERNATIONAL 1/2 – 2001
Abstract: Ostapenko V. et al. (Minsk and New Tork), observed 5965 people, aged 18 or below, at the moment of the Chernobyl disaster, who had lived in the contaminated territories. Peroxidase antibodies to thyrocytes and / or thyroglobulin (TG) were observed in 6.3% of the patients (in women 2 times more often than in men) ….
URL: http://www.thyronet.ru/spetsialistam/zhurnal/archiv/2001g/2/2_36.html?page=3
Author: Ulla Feldt-Rasmussen (Copenhagen, Denmark)
Reference: Thyroid international – 1-1996
Journal Thyronet 2001 / / № 1.
Keywords: Chernobyl, Hiroshima, thyroid cancer
Abstract: … The thyroid gland is an organ most sensitive to the effects of radiation: this was evidenced by the increasing incidence of cancer among children in the Chernobyl area after the accident at its nuclear power plant in 1986, as well as by a delayed increase of incidence of thyroid cancer among the population having survived the atomic bombardment of Hiroshima …
URL: http://www.thyronet.ru/spetsialistam/zhurnal/archiv/2001g/1/Lechenie_raka_schitovidnoi_jelezy.html?page=1
Author: G.A. Gerasimov, V.V. Fadeyev, N.Yu. Sviridenko et al.
Reference: Second chapter of the book “Йододефицитные заболевания в России – простое решение сложной проблемы” (“Iodine-deficit-related diseases in Russia – simple solutions to difficult problems”)
in Journal Thyronet, 2002, No. 4
URL: http://www.thyronet.ru/spetsialistam/zhurnal/archiv/2002g/4/Vrachi_ili_likvidatory_posledstvii_iodnogo_deficita.html?page=11
Reference: Journal Thyronet 2002 № 1-2
Abstract: Ostapenko et al. (Minsk, Belarus; New York, USA) investigated the relationship between the level of urinary iodine excretion, thyroglobulin (TG), thyroid volume and the incidence of thyroid cancer and nodular goiter among 11,200 inhabitants of Belarus, who, at the time of the accident, were under 18 years of age.
URL: http://www.thyronet.ru/spetsialistam/zhurnal/archiv/2002g/1-2/Materialy_73go_ejegodnogo_sezda_Amerikanskoi_Tireoidologicheskoi_Associacii.html?page=0
Reference: Journal Thyronet 2002 № 1-2
Keywords: Comments by Hennemann G., Rotterdam (Netherlands)
Abstract: Ostapenko V., et al. (Minsk, Belarus; Bethesda, New York, USA) examined the level of TG in 9334 of inhabitants of Belarus, residing in a region of moderate iodine deficiency, aged, at the time of the Chernobyl accident, 0 – 18. Among the examinees, 4671 did not show any pathology of the thyroid gland, whereas 53 showed papillary thyroid cancer, 496 showed solitary nodules in the thyroid gland, and 198 showed multinodular goiter. Compared with the first group (control), the other three showed a statistically significant increase in triglycerides.
URL: http://www.thyronet.ru/spetsialistam/zhurnal/archiv/2002g/1-2/Materialy_27go_ejegodnogo_sezda_Evropeiskoi_Tireoidologicheskoi_Associacii.html?page=7
Reference: Journal Thyronet / / 2003 / / № 2
Abstract: Kuchinskaya EA, et al. (Minsk, Belarus) examined the level of AT-TG and TPO (thyroid peroxidase) antibodies in 157 children and adolescents with AIT and 126 patients with type 1 diabetes mellitus (DM-1). It was found that in patients with autoimmune thyroiditis residing in Gomel, who were exposed to radiation during the Chernobyl accident, the level of AT-TG and TPO antibodies were significantly higher (p <0,05), compared to patients who live in Minsk, who was not radioactively contaminated. Similarly, the prevalence of carriage of AT-TPO was higher among patients with type-1 diabetes mellitus from Gomel, compared with patients from Minsk (40% vs 27%; p <0,05).
URL: http://www.thyronet.ru/spetsialistam/zhurnal/archiv/2003g/2/Materialy_28_ejegodnogo_sezda_Evropeiskoi_Tireoidologicheskoi_Associacii.html?page=2
Author: DE, Shilin
Reference: Журнал Тиронет (Journal Tironet) / / 2000 / / № 3
Abstract: The aim of our study was a retrospective analysis of data obtained, during 1992-97, from the Russian fragment of the International project “Thyroid gland: a standardized analysis of iodine sufficiency in Europe” (“Tiromobil-97″ in the Belgorod and Voronezh regions), Federal Program “Children of Chernobyl” (Orel region, observed after the accident at the Chernobyl nuclear power plant areas), and surveys on schoolchildren in Moscow. All these areas belong to regions with iodine deficiency (mild to moderate). Comprehensive discussion is given on data obtained on a samples of almost three thousand children aged 6 to 15 (number = 2939).
URL: http://www.thyronet.ru/spetsialistam/zhurnal/archiv/2000g/3/K_voprosu_o_vnedrenii_mejdunarodnyh_normativov_ultrazvukovogo_obema_schitovidnoi_jelezy_v_pediatricheskuyu_praktiku.html
