Title: Nucleotide variation in the p53 tumor-suppressor gene of voles from Chernobyl, Ukraine.
Author: DeWoody JA.
Reference: Mutat Res. 1999 Feb 2;439(1):25-36.
Keywords:
Abstract: The 1986 Chernobyl disaster contaminated vast regions of Ukraine and Belarus with a variety of radioactive isotopes and heavy metals. While over 90% of the radioactive isotopes have decayed into stable compounds, radiation levels in contaminated areas are still extraordinarily high. In fact, some rodents living near the reactor have internal 134,137Cs concentrations approaching 80 000 Bq/g. Several recent genetic analyses of vertebrates have illustrated that mutation rates of organisms exposed to radiation from Chernobyl are higher than in control groups, but none have studied DNA sequences. Nucleotide sequences of rodent mitochondrial genes were originally reported to have been hypervariable, but those results were subsequently retracted. Herein, I report the results of a pilot study to determine the extent of nucleotide variation at the p53 gene in four species of rodents (voles) from Chernobyl and from control sites. I sequenced a 788 bp region (coding and non-coding) of p53 in 30 different mice comprising four different species of Microtus. Nucleotide variation at the population level was due to deletions and substitutions; both were limited to introns. There were no significant differences between the number of haplotypes in radioactive and control populations (p=0.60). Rare or private alleles might have arisen due to unique mutational pressures at Chernobyl. Alternatively, natural selection might have favored one allele over others (i.e., a selective sweep). Neither scenario is strongly supported by these data. Thus, no apparent genetic effects of the Chernobyl disaster on the p53 gene of resident voles were revealed; more extensive surveys will be necessary to determine if mutation rates are indeed elevated in mice from Chernobyl. However, two salient points emerge; the first involves the utility of introns as markers for mutations in coding regions and the second considers the relative merits of cloning in mutation detection studies.
ＵＲＬ：http://www.ncbi.nlm.nih.gov/pubmed/10029670
Title: Preliminary evaluation of the impact of the Chernobyl radiological contamination on the frequency of central nervous system malformations in 18 regions of Europe
Reference: Paediatric and Perinatal Epidemiology, Volume 2, Issue 3, pages 253–264, July 1988
DOI: 10.1111/j.1365-3016.1988.tb00216.x
Keywords: human breast milk; Iodine-131; nuclear power plant accident; radioiodine
Abstract: The teratological impact of radiological contamination from the Chernobyl accident was evaluated in relation to central nervous system and eye defects in 18 regional registries in nine countries of Western Europe. Six classes of anomaly were analysed: neural tube defects, arhinencephaly, microcephaly and brain reduction, hydrocephaly, anophthalmos and microphthalmos, and congenital cataract. Conceptions up to 31 August 1986 were grouped into two exposure cohorts. In cohort A the sensitive period of fetal development to radiation fell wholly or partly between 1 May and 30 June 1986. Cohort B included all cases exposed during their sensitive period on or after 1 May 1986. Observed frequencies of the six classes of anomaly in the exposed cohorts were compared with expected frequencies calculated from baseline rates for the period 1980–1985. The only significant increase was neural tube defects in Odense, Denmark (four cases observed in cohort A where 0.9 were expected). The results of the study do not show a general increase in the frequency of malformations in the countries of Western Europe. The evidence presented indicates that, in the regions studied, termination of pregnancies or invasive prenatal diagnostic examinations were not justified for women exposed during pregnancy.
URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1365-3016.1988.tb00216.x/abstract
Author: Valentin Golosov
Reference: Soil and Tillage Research, Volume 69, Issues 1–2, February 2003, Pages 85-98
DOI: http://dx.doi.org/10.1016/S0167-1987(02)00130-7
Keywords: Chernobyl; ; Soil redistribution; Erosion; Method
137Cs, Soil redistribution, Erosion
Abstract: Vast areas of Europe were contaminated by the Chernobyl-derived in April–May 1986. This paper reports a detailed study of the post-fallout redistribution within a 1 ha field located in the Chasovenkov Verh catchment in the northern part of the Middle-Russian upland. Particular attention was paid to the study of reference inventories. It is shown that the random spatial variability of is similar within undisturbed and cultivated parts of a flat interfluve. Systematic spatial variability is not essential for a relatively short (200 m) topographical unit with simple relief. The analysis of a soil redistribution pattern within the study field using the Chernobyl technique demonstrates that it is possible to identify areas of soil loss/gain. This pattern does not reflect soil redistribution for the whole field, because these have been only 12 years since the Chernobyl accident. Net erosion rates based on method were comparable to soil losses directly measured at the study field.
Author: Ludwika Kownacka, Zbigniew Jaworowski
Reference: Science of The Total Environment, Volume 144, Issues 1–3, 29 April 1994, Pages 201-215
DOI: http://dx.doi.org/10.1016/0048-9697(94)90439-1
Keywords: Radionuclides; Troposphere; Stratosphere; Nuclear tests; Chernobyl
Radionuclides , 90Sr, 137Cs, Troposphere, Stratosphere, 134Cs, Nuclear tests
Abstract: High altitude aircraft sampling of aerosols has been carried out at 4–7 levels up to 15 km over Poland. From 1973 to 1991 a total of 102 vertical concentration profiles of 90Sr, 134Cs and 137Cs, and 83 profiles of 144Ce were determined. One year after the sub-megaton nuclear test in 1980, 137Cs was almost completely removed from the stratosphere. The Chernobyl debris was found in the stratosphere from the third day after the accident until the end of 1991. In May 1986 the concentration of 134Cs and 137Cs at stratospheric altitudes reached about 0.5% of that between the ground level and 3 km. Residence times of Chernobyl radiocesium in the lower stratosphere systematically increased between 1987 and 1991, in variance with those of the debris from nuclear tests. The vertical concentration profiles and the long residence times of radiocesium indicate that the non-violent meteorological processes were transporting the Chernobyl debris into the lower stratosphere, immediately and long after the accident. We postulate that the same quiescent processes transport vast amounts of resuspended particulate organics from the surface of land and sea into high altitudes, and may thus bear on the chemistry of the stratosphere.
URL: http://www.sciencedirect.com/science/article/pii/0048969794904391
Title:Effects of physical rehabilitation of the liquidators of the Chernobyl accident with chronic pulmonary pathology
Author: CHIKINA S.YU., MESCHERYAKOVA N.N., CHERNYAK A.V., BELEVSKIY A.S., CHUCHALIN A.G.
Reference: Journal of modern clinical medicine. 2008, No.1
Annotation: The influence of physical rehabilitation on the dynamics of functional state of Chernobyl atomic electric station accident liquidators. Physical reabilitation improves tolerance to physical execises, but does”t influence pulmonary function probably because of the fact that special exercises for respiratory muscle weren”t included intothe programm of rehabilitation.
Key words:CHERNOBYL ATOMIC ELECTRIC STATION ACCIDENT LIQUIDATORS , TOLERANCE TO PHYSICAL EXERCISES , RADIONUCLID-INDUCED PNEUMOPATHY
http://cyberleninka.ru/article/n/effekty-fizicheskoy-reabilitatsii-u-likvidatorov-avarii-na-chaes-s-hronicheskoy-bronholegochnoy-patologiey#ixzz3aSvr5hwP
Title: Analysis of mortality of Chernobyl APP accident’s liquidators living on the territory of Tomsk region
Author: Krayushkina N.P., Chernogoryuk G.E., Fateyeva S.N., Lazareva L.M., Solomakhina N.V., Yermolova S.V.
Reference:
Keywords: population health state, mortality, statistics, accident at Chernobyl APP.
Abstract: The dearth-rate is a common reference point for the population health state. Mortality coefficient in the second decade after the accident at Chernobyl APP increased at the average by 50%.
URL:http://www.fesmu.ru/elib/Article.aspx?id=134026
Title: Peculiarities of hemopoiesis in Chernobyl event liquidators who live in the Tomsk region
Author: Porovsky Ya.V., Domnikova R.S., Tetenev F.F.
Reference: Siberian State Medical University
Keywords: Chernobyl event liquidators, peripheral blood, bone marrow.
Abstract: Results of peripheral blood analysis, performed annually during 12—14 years in 83 Chernobyl event liquidators and of the marrow which was analyzed once, at the end of abovementioned period in 23 participants are given. Changes in peripheral blood showed increased number of reticulocytes, lymphocytes, monocytes and decreased number of thrombocytes. Cellular structure of the marrow revealed decreased mean number of myelocytes, basophil and polychromatophil normoblasts and increased number of lymphoid and monocyte population cells. The deflections revealed in the hemopoiesis system may serve as reflection of continuing regeneration processes in the bone marrow and increased amount of somatic pathologies.
URL: http://mognovse.ru/qco-osobennosti-gemopoeza-u-likvidatorov-posledstvij-avarii-na.html
Title: MOLECULAR MECHANISMS OF CELL ALTERATIONS CAUSED BY CHRONIC EXPOSURE TO LOW INTENSITY IONIZING RADIATION DUE TO CHERNOBYL ACCIDENT
Author: E.P. Sidorik*, A.P. Burlaka R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy
Reference: Experimental Oncology 22, 179-185, 2000 (December) 179
Keywords:
Abstract:
URL: http://exp-oncology.com.ua/wp/wp-content/uploads/magazine/121.pdf?upload=
- Title: THE IMPACTS OF THE CHERNOBYL NUCLEAR DISASTER ON THE FOREST VEGETATION OF THE POLISSYA REGION OF UKRAINE
Author: Dr. Mykolai Kaletnik, Dr. Petro Pasternak, Dr. Serhei Hrisiuk, Yurij Bihun
Reference:
doi:
Keywords:
Abstract: In the spring of 1986, the aftermath of the Chernobyl nuclear explosion left a substantial portion of the forested area of the Ukrainian Polissya region contaminated with radioactive fallout. Although less than 14.5% of Ukraine is forested, nearly one-quarter (24.2%) of its woodlands (appox.2,371,600 ha) are located in the Polissya region.
URL: http://ces.iisc.ernet.in/hpg/envis/proceed/kaletnik.txt.html
Title: Condition of peripheral blood system in children and adolescents, who are living in radiated polluted area (study in 10 years after Chernobil accident).
Author: Dubey L.Ya.
Reference: 14.01.310 – pediatria. – Kharkov state Medical University, the Ministry of Public Health, Kharkov, 2001.
Key words: children, adolescents, peripheral blood system, inner radiation, environment pollution.
Annotation:This work is devoted to a problem of influence of low doses radiations on peripheral blood in children and adolescents, who are living in northern areas of Zhitomir region.The conditions of children’s health, who are living in radiated polluted area was studied. Children’s deaseses at postaccident period was investigated. Total and characteric changes of health conditions due to low doses radiations was determined. The epidemiology of inner radiation toward incorporation radiocezium level was studied. Different inner radiation doses influence on blood system was investigated.Peripheral blood conditions data in children and adolescents due to radiated polluted environment and tot al inner radiotions activity was determined. The correlative analisis of different peripheral blood data in children and adolescents due to the level of` inner radiotions density activity was performed.
