Assessment of the health of children and adolescents living in the contaminated areas of the Kaluga region as a result of the accident at the Chernobyl nuclear power plant, using a computer automated system of summarizing medical dosimetry Inspections

Author: V.V. Stukalova

Reference: Dissertation, Obninisk, 2002

Keywords: health care, low-dose radiation, monitoring

Abstract: Modern radio-biological concept of low doses of ionizing radiation and the organization of the study of radiation accidents (literature review)

1.1. The impact of low-dose radiation on biological objects and systems

1.2. Epidemiological data on the effects of low-dose radiation

1.3. Organizational aspects of health care provision in radiation accidents and conducting of long-term monitoring of affected individuals

Radioecological situation in the Kaluga region after the Chernobyl accident, the radiation dose of the population. Total volume of the research methodology and analysis of the dynamic monitoring of the health of the pediatric population in the years 19921996. (Materials and Methods) …

URL: http://www.dissercat.com/content/otsenka-sostoyaniya-zdorovya-detei-i-podrostkov-prozhivayushchikh-na-zagryaznennykh-radionuk

Improvement of methods of diagnosis and treatment of thyroid tumors in children and adolescents (on the model of the Rostov region).

Author：Yu.Yu. Kozel

Reference: Dissertation, doctor of medical sciences, Roftov-na-Donu, 2006

Keywords: children, adolescence, immune-genetic research

Abstract: 20 years after the accident of the Chernobyl nuclear power plant, it becomes all the more clear, by facts, that sharp increase in the incidence of thyroid cancer, especially malignant tumors, has become the basic health effects of radiation. Most tragically, the above mentioned fact is observed among persons who, at the time of the accident, were children or teenagers and were exposed to radioactive iodine (Vtyurin BM et al., 2003). …

Aim of research: to develop tactics of examination of children and adolescents with thyroid tumors, based on the analysis of clinical and diagnostic data, including usage of immune-genetic studies. Optimization of method to treat these diseases, considering the immune-genetic characteristics of the child.

URL: http://www.dissercat.com/content/usovershenstvovanie-metodov-diagnostiki-i-lecheniya-opukholei-shchitovidnoi-zhelezy-u-detei-

Comprehensive diagnosis and treatment of thyroid cancer based on etiopathogenetic and prognostic factors

 Author: P.O. Rumyantsev

Reference: Dissertation, doctor of medical sciences, Obninsk, 2009

Keywords: children, adolescence, histological verification, English researchers, Thomas GA & Williams E.D.

Abstract: … Since 1992 to the present time, in the contaminated territories of the Russian Federation, following the accident at the Chernobyl nuclear power plant, were detected an abnormally high incidence of thyroid cancer in the cohort of individuals exposed in childhood and adolescence [BM Vtyurip et al, 2001]. In the late ’90s, for a review, a histogram-preparation of all previously diagnosed cases of thyroid cancer was available for an independent examination by the international panel of pathologists, chaired by Professor Williams (UK). As result of the independent histological verification, in many cases the diagnosis of thyroid cancer was not confirmed, in some cases histological type was changed, or histopathological version of the thyroid carcinoma was elaborated. Since 1999 histo-preparation of all newly diagnosed cases of thyroid cancer in children and adolescents, (at the time of diagnosis or at the time of the Chernobyl accident) born after 1967, has undergone regular independent histological verification as part of international projects of bank of tissue, blood and nucleic acids, whose headquarter is situated in London [Thomas GA & Williams E.D., 2001]. After more than twenty years after the Chernobyl accident, there is no information on the exact number of cases of thyroid cancer (based on the results of the international histological verification) reported of children and adolescents in the contaminated territories of the Russian Federation in the post-Chernobyl period ….

URL: http://www.dissercat.com/content/kompleksnaya-diagnostika-i-lechenie-raka-shchitovidnoi-zhelezy-na-sonove-etiopatogenetichesk

The clinical progress and remote results of surgical treatment of thyroid cancer in children and adolescents

Author: S.V. Osipov

Reference: Dissertation, candidate of medical sciences, Ufa, 2005

Keywords: surgical treatment, remote long-term consequences, survival rate

Abstract: Scientific novelty of the work:

1. For the first time an analysis of the clinical course and remote results of surgical treatment of thyroid cancer, in children and adolescents in the region of the Southern Urals, (Chelyabinsk region) in terms up to 25 years, is shown.

2. The clinical course of thyroid cancer in children and adolescents is defined by the presence symptom complex – a painless lump in the neck, an increase in cervical lymph nodes under the guise of “banal” adenopathy with a predominance of well-differentiated thyroid carcinomas.

3. Conserving surgical treatment of differentiated thyroid cancers, in children and adolescents, is to provide excellent immediate long-term results.

4. The cumulative survival rate after surgical treatment of highly differentiated form of thyroid cancer, in children and adolescents in terms of supervision of up to 25 years, – 94.0%.

URL: http://www.dissercat.com/content/klinicheskoe-techenie-i-otdalennye-rezultaty-khirurgicheskogo-lecheniya-raka-shchitovidnoi–0

Comparative assessment of indicators of overall level and patterns of disease with cytogenetic indices in children and adolescents living in the contaminated areas of the Kaluga Region after the accident of the Chernobyl nuclear power plant

Author: N.O. Omapaskhabov

Reference: Dissertation, 2007

Keywords: demography, somatic abnormalities, digestive system

Abstract: For the first time, a comprehensive comparative evaluation is carried out of the dynamics of demographic indicators, indicators of the overall level and structure of newly diagnosed disease, as well as cytogenetic indices in child population living for 20 years in the contaminated areas following the accident of the Chernobyl nuclear power plant. Implements, in the initial -“iodine”- period of the Chernobyl accident, direct measurements of absorbed doses of the thyroid gland (TG) in children of Zhizdra area, allowing, for the first time, to evaluate the observed functional changes in the thyroid depending on the individual doses of incorporated radionuclides of iodine. Determines the role of cytogenetic damage in the development of somatic abnormalities in children with elevated levels of chromosomal aberrations. Especially in prenatally irradiated cases, morphological and functional changes in the thyroid gland diseases in the respiratory and digestive system, are more often encountered. The results obtained in general: Materials of the research formed the basis for the planning of socio-economic measures and medical administration of the Kaluga region in the contaminated areas after the Chernobyl accident …

URL: http://www.dslib.net/radio-bio/sravnitelnaja-ocenka-pokazatelej-obwego-urovnja-i-struktury-zabolevaemosti-s.html