The dependence of incidence rates of non-cancer thyroid diseases in the post-natal period at the Kaluga oblast children from term gestation, on which has taken place them in utero irradiation owing to technogenic iodine-131 incorporation

Title: The dependence of incidence rates of non-cancer thyroid diseases in the post-natal period at the Kaluga oblast children from term gestation, on which has taken place them in utero irradiation owing to technogenic iodine-131 incorporation

Author: Gorobets V.F

Reference: Radiation and Risk (Bulletin of the National Radiation and Epidemiological Registry) Year: 2011 Volume: 20 Issue: 1

Keywords: children, incidence of non-cancer thyroid diseases, irradiation in utero, technogenic iodine-131, cohort study

Abstract: The results of investigation of non-cancer thyroid diseases incidence rates, relative risks and etio-logic fractions by cohort study at 420 children from southwest region of the Kaluga oblast for the 12-year’s period after irradiation in utero on various terms of gestation at the expense of the technogenic iodine-131 incorporation are presented. Also 150 not exposed children as the control group was observed. It was established that incidence rates of thyroid diseases in the children irradiated in utero was at 2.6 times more than in the control group. The incidence of thyroid diseases among the children irradiated in utero was depended on the period of gestation at which irradiation was occurred. The highest level of the thyroid diseases incidence rate was in two subgroups of irradiated children: in the first subgroup every member was irradiated at the expense of iodine-131 from 4-th to 12-th week of gestation, in the second subgroup – from 16-th to 22-th week of gestation. It is known from radiobiological investigations that at these periods of gestation thyroid of foetus intensively accumulates radioactive iodine.

URL:http://cyberleninka.ru/article/n/zavisimost-urovney-zabolevaemosti-neonkologicheskimi-zabolevaniyami-schitovidnoy-zhelezy-v-postnatalnom-periode-u-detey-iz-kaluzhskoy

Selection of the cohort for the long-term clinical follow-up and assessment of radiation risks for thyroid diseases under the Joint Medical Research Project conducted by Sasakava Memorial Health Foundation and MRRC of RAMS

Title: Selection of the cohort for the long-term clinical follow-up and assessment of radiation risks for thyroid diseases under the Joint Medical Research Project conducted by Sasakava Memorial Health Foundation and MRRC of RAMS

Author: Ivanov V.K., Tsyb A.F., Pitkevich V.A., Maksyutov M.A., Маtveenko Е.G., Khvostunov I.К., Rastopchin Е.М., Sorokin V.S., Ivanov S.I., Leshakov S.Y., Shiryaev V.I., Borovikova М.P., Efendiev V.A., Kvitko B.I., Shibata Y., Yamashita S., Hoshi M.

Reference: Journal　“RADIATION AND RISK” No.8  1996

doi:

Keywords: Cohort

Abstract: The description of the cohort of the children of Bryansk and Kaluga regions of Russia exposed to radioiodine in 1986 as a result of the Chernobyl accident is given in the paper. The cohort has been selected under the Joint Medical Research Project on Thyroid disease conducted by Sasa-kava Memorial Health Foundation and MRRC of RAMS for the long-term clinical follow-up of the thyroid. It comprises 3299 persons, 1187 of them are residents of Bryansk region and 2112 – residents of Kaluga region. All subjects were under 10 years old at the time of exposure. All members of the cohort have individual radiometric data for thyroid obtained in May-June of 1986. The main part of the subjects lived in the most contaminated areas of Bryansk and Kaluga regions in 1986. The preliminary evaluation of absorbed radiation doses to thyroid has been performed before the verification of incorporated activity of 131I in thyroid, dynamics of radioiodine deposits in the territory of Russia as well as specialised cross-examination of the cohort members. Analysis of the results has shown that statistical distribution of the absorbed doses of internal exposure of thyroid is close log normal distribution with mean value of 240 mGy and standard deviation of 750 mGy for Bryansk part of the cohort, and 360 mGy – for Kaluga one. In 5% of the members the absorbed radiation dose in thyroid is under 1 mGy, the maximal one is 12 Gy for the Bryansk part of the cohort and 6 Gy for the Kaluga part. One of those who were followed up within the decade after the Chernobyl developed thyroid cancer. For the next period of the follow-up by the cohort study technology radiation risks of developing thyroid cancer and non-cancer thyroid diseases are planned to be assessed.

URL: http://elibrary.ru/item.asp?id=9320742

U.S./Belarus/Ukraine joint research on the biomedical effects of the Chernobyl Reactor Accident. Final report

Title: U.S./Belarus/Ukraine joint research on the biomedical effects of the Chernobyl Reactor Accident. Final report

Author: Bruce Wachholz

Reference: Other Information: PBD: 20 Jun 2000
doi: 10.2172/760446

Keywords: children, cohort,cleanup workers

Abstract: The National Cancer Institute has negotiated with the governments of Belarus and Ukraine (Ministers/Ministries of Health, institutions and scientists) to develop scientific research protocols to study the effects of radioactive iodine released by the Chernobyl accident upon thyroid anatomy and function in defined cohorts of persons under the age of 19 years at the time of the accident. These studies include prospective long term medical follow-up of the cohort and the reconstruction of the radiation dose to each cohort subject’s thyroid. The protocol for the study in Belarus was signed by the US and Belorussian governments in May 1994 and the protocol for the study in Ukraine was signed by the US and Ukraine in May 1995. A second scientific research protocol also was negotiated with Ukraine to study the feasibility of a long term study to follow the development of leukemia and lymphoma among Ukrainian cleanup workers; this protocol was signed by the US and Ukraine in October 1996.

URL: http://www.osti.gov/bridge/product.biblio.jsp?query_id=2&page=0&osti_id=760446

Suicide Risk Among Chernobyl Cleanup Workers in Estonia Still Increased: An Updated Cohort Study

Title: Suicide Risk Among Chernobyl Cleanup Workers in Estonia Still Increased: An Updated Cohort Study
Author: Rahu, Kaja / Rahu, Mati / Tekkel, Mare / Bromet, Evelyn

Reference: Annals of Epidemiology, 16 (12), p.917-919, Dec 2006

doi: 10.1016/j.annepidem.2006.07.006

Keywords: Chernobyl; Cohort; Mortality; Suicide; Estonia

Abstract: …chance finding because brain cancer is not considered to be related…although the incidence of brain cancer in our Chernobyl cohort also was elevated in 1986 to 1998 (7) . Thyroid cancer and leukemia are related to ionizing…

URL: http://www.sciencedirect.com/science/article/pii/S104727970600192X

Increased incidence of malignancies in Sweden after the Chernobyl accident-a promoting effect?

Title: Increased incidence of malignancies in Sweden after the Chernobyl accident-a promoting effect?

Author: Martin Tondel, Peter Lindgren,1 Peter Hjalmarsson,Lennart Hardell, Bodil Persson4

Reference: AMERICAN JOURNAL OF INDUSTRIAL MEDICINE 49:159–168 (2006) [PDF-140K]Mar 2011

Keywords: caesium-137; ionising radiation; nuclear power; low dose; epidemiology; environment; background radiation; cancer; GIS; cohort

Abstract: After the Chernobyl accident in 1986, as much as 5% of the released caesium-137 was deposited in Sweden due to a heavy rainfall 2 days after the event. A study of increased incidence of malignancies was initiated after the accident.

URL: http://www.ippnw.org/pdf/chernobyl-increased-incidence-malignancies-sweden.pdf