Indicators of biological age and accelerated aging in liquidators of the consequences of radiation emergency

Title: Indicators of biological age and accelerated aging in liquidators of the consequences of radiation emergency

Author: E. I. Puchkova, N. V. Alishev

Reference: Advances in Gerontology , October 2011, Volume 1, Issue 4, pp 346-351

DOI: 10.1134/S2079057011040151

Keywords: biological age, accelerated aging, social-hygienic factors, functional classes of biological age, radiation accidents, medical consequences

Abstract: The biological age (BA) of the majority of liquidators of the consequences of radiation accidents in the navy and of the liquidators of the Chernobyl NPP accident exceeds the average standard and their DBA (due BA). The BA index can be a characteristic of the influence of social-hygienic factors on the health conditions in the Special Risk Subunit whose members liquidated the consequences of the radiation accidents. It was established that the radiation effect pertains to factors dramatically increasing BA and the rate of senescence in this group of people.

ＵＲＬ：http://link.springer.com/article/10.1134/S2079057011040151

Mental function following scalp irradiation during childhood

Author: E. Ron, B. Modan, S. Flora et al.

Reference: Am. J. Epidemiol. — 1982. — Vol. 116. — P. 149–160.

Keywords: tinea captis treatment, radiation therapy, neurological consequences

Abstract: Between 1950 and 1960 about 20,000 israeli children were treated for tinea capitis by x-ray therapy as part of a large public health campaign to eradicate the disease. Dosimetric studies determined that these children were subjected to a mean brain dose of 130 rads. Almost 20 years later, possible radiation effects on the central nervous system were evaluated by comparing several measures of mental and brain function in approximately 11,000 of the irradiated children and in two nonirradiated, tinea-free comparison groups: (a) ethnic, sex- and age-matched individuals from the general population, and (b) siblings. While not all comparisons were statistically significant, there was a consistent trend for the irradiated subjects to exhibit signs of central nervous system inpairment more often than either comparison group. The irradiated children had lower examination scores on scholastic aptitude, intelligence quotient (IQ) and psychologic tests, completed fewer school grades, and had an increased risk for mental hospital admissions for certain disease categories. A slightly higher frequency of mental retardation was also suggested. These-long-lasting scholastic and mental health effects lead the authors to conclude that radiation to the immature brain may cause damage to the central nervous system.

URL: http://www.ncbi.nlm.nih.gov/pubmed/7102650

Medical effects of ionizing radiation

Author: F.A. Mettler, A.C. Upton (Eds.).

Reference: 2^nd ed. — Philadelphia: Saunders W. B. Company, 1995. — 464 p

View of Pathologist on Medical Consequences of the Chernobyl Accident: Neoplasms

Title: View of Pathologist on Medical Consequences of the Chernobyl Accident: Neoplasms

Author: Lushnikov E.F

Reference: Journal” МЕДИЦИНСКАЯ РАДИОЛОГИЯ И РАДИАЦИОННАЯ БЕЗОПАСНОСТЬ“53- 1 : 2008

ISSN: 0025-8334

Keywords: CHERNOBYL ACCIDENT,  MEDICAL CONSEQUENCES, NEOPLASMS, THYROID CARCINOMA

Abstract: Purpose: To review medical consequences of the Chernobyl accident taking oncological morbidity and mortality in population as example. Material and methods: Data of the demographic and medical statistics of oncological morbidity and mortality as well as results of studies fulfilled by colleagues of the laboratory of pathological anatomy headed by author of the paper were used. Results: It was established that morbidity and mortality rates of malignant neoplasms that could be/not be related to consequences of the accident were varied in different regions of Russia. Completeness and reliability of the data of oncological statistics were acceptable for the public health organization but insufficient for assessment of medical consequences of the accident for past years and estimation of risks for population morbidity and mortality resulted from malignant tumors that could be induced by ionizing radiation as the statistics does not take into consideration the peculiarities of the onco-nosological forms. There were several reasons (difficulties of diagnostics, death of the majority of patients at home, lack or insufficient pre- or post-mortal morphological diagnosis verification, low quality of medical and statistical documentation) that created obstacles for improvement of the quality of medical information. More reliable data of morbidity and mortality in population exposed to the accidental radiation could be obtained from the special registry based on the information that controlled by morphological verification of diagnosis. Analysis of morbidity and mortality in accordance with the 1CD-10 can not provide any notion about relationship between pathology and various factors of accident as each of onco-nosological form has own etiological, pathogenetical, clinico-anatomical peculiarities and should be specially analyzed.

URL: http://elibrary.ru/item.asp?id=10019507