The Chernobyl accident and its consequences: Update at the millennium
Title: The Chernobyl accident and its consequences: Update at the millennium
Author: Tuttle, R. Michael / Becker, David V.
Reference: Seminars in Nuclear Medicine, 30 (2), p.133-140, Apr 2000
doi: 10.1053/nm.2000.5412
Abstract:…However, several unique chromosomal break-points have been described in radiation-associated thyroid cancers that are not commonly found in spontaneously occurring thyroid cancer. Furthermore, activation of specific subtypes of the ret/PTC tyrosine kinase oncogene appears to be more common in radiation-associated thyroid cancers than in spontaneous thyroid cancers. In summary, thyroid cancers developing in the aftermath of the Chernobyl accident provide a unique opportunity to search for chromosomal abnormalities that may be specific for radiation-induced thyroid cancer.
URL: http://www.sciencedirect.com/science/article/pii/S0001299800800501
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