The impact of ionizing radiation on placental trophoblasts

Title: The impact of ionizing radiation on placental trophoblasts

Author: D.J. Kanter, M.B. O’Brien, X.-H. Shi, T. Chu, T. Mishima, S. Beriwal, M.W. Epperly, P. Wipf, J.S. Greenberger, Y. Sadovsky

Reference: Placenta, Volume 35, Issue 2, February 2014, Pages 85-91

doi: http://dx.doi.org/10.1016/j.placenta.2013.12.011

Keywords : Placenta; Trophoblast; Ionizing radiation; Microarray; JP4-039

Abstract: Exposure to low-dose radiation is widespread and attributable to natural sources. However, occupational, medical, accidental, and terrorist-related exposures remain a significant threat. Information on radiation injury to the feto-placental unit is scant and largely observational. We hypothesized that radiation causes trophoblast injury, and alters the expression of injury-related transcripts in vitro or in vivo, thus affecting fetal growth.

ＵＲＬ: http://www.sciencedirect.com/science/article/pii/S0143400413008710

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