Thyroid and antithyroid drugs
Title: Thyroid and antithyroid drugs
Author: Bouillon, R.
Reference: Side Effects of Drugs Annual, 13, p.375-380, Jan 1989
doi: 10.1016/S0378-6080(89)80048-0
Keywords:
Abstract: The adjustment of the thyroxine replacement dosage has been debated for several years. The minimum dose can be defined as the amount that normalizes serum TSH, and the maximum dose as the amount that increases serum T3 to the supranormal range. The chapter talks about the studies on effects of administering thyroid drugs and notes that the ultimate evaluation of such therapy awaits, however, better randomized prospective studies instead of the present retrospective analysis. It also cites studies on antithyroid drugs and notes that classical antithyroid drugs, however, by their effect on inhibiting the new synthesis, but not the secretion of existing hormones, only normalize thyroid hormone concentrations after one to several weeks. The chapter also mentions some side effects like agranulocytosis and polymyositis. There is also a discussion about some studies on Antithyroid drugs, pregnancy, and skin defects. Iodine and the iodides have also been explained.
…used for the treatment of thyroid carcinoma can increase the…1311 because of metastatic thyroid carcinoma (27c). Testicular…Exposure to 131I after the Chernobyl inci- dent in travellers returning from Eastern Thyroid and antithyroid drugs Chapter…
URL: http://www.sciencedirect.com/science/article/pii/S0378608089800480
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