カテゴリー「thyroid cancer」
Title: Thyroid cancer has increased in the adult populations of countries moderately affected by Chernobyl fallout.
Author: Mürbeth, St.*, Rousarova, M.*, Scherb, H., Lengfelder, E.*:
Reference: Med. Sci. Monit. 10, 300-306 (2004)
Keywords: Czech Republic
Abstract: The incidence of thyroid carcinoma increased among children affected by Chernobyl fallout. Less evidence exists for a corresponding effect in adolescents and adults. The Cancer Registry of the Czech Republic provides an opportunity to study various determinants of the occurrence of thyroid cancer.
URL: http://www.ncbi.nlm.nih.gov/pubmed/15295858
Title: A radioecological model for thyroid dose reconstrucion of the Belarus population following the Chernobyl accident.
Author: Kruk, J.E.*, Pröhl, G., Kenigsberg, J.I.*:
Reference: Radiat. Environ. Bioph. 43, 101-110 (2004)
doi:10.1607/s 004-0241-z
Keywords: Belarus
Abstract: A radioecological model was developed to estimate thyroid exposures of the Belarus population following the Chernobyl accident. The input of the model includes an extensive data set of the 137Cs activity per unit area deposited during the Chernobyl accident, the rainfall data for different regions of Belarus, the 131I/137Cs ratio in the deposit and the start of the grazing period in Belarus in April/May 1986. The output of the model is the age-dependent thyroid exposure due to the intake of 131I with fresh milk. Age-dependent average thyroid doses were assessed for selected regions of Belarus. The maximum thyroid doses were estimated for the inhabitants of Gomel oblast where the highest deposition was observed among the regions considered here. The lowest doses were estimated for Vitebsk oblast with the lowest level of depositions. The mean exposures for the oblasts of Grodno, Minsk, Mogilev and Brest were very similar. The results were compared with estimations of thyroid exposure that were based on 131I measurements in human thyroids, and they are in good agreement. The model may be used for the assessment of thyroid doses in Belarus for areas where no 131I measurements are available.
URL: http://link.springer.com/article/10.1007/s00411-004-0241-z#
Title: INDIVIDUAL THYROID DOSE ESTIMATION FOR A CASE-CONTROL STUDY OF CHERNOBYL-RELATED THYROID CANCER AMONG CHILDREN OF BELARUS-PART I: 131I, SHORT-LIVED RADIOIODINES (132I, 133I, 135I), AND SHORT-LIVED RADIOTELLURIUMS (131MTe AND 132Te)
Author: Gavrilin, Yuri*; Khrouch, Valeri*; Shinkarev, Sergey*; Drozdovitch, Vladimir†; Minenko, Victor‡; Shemiakina, Elena§; Ulanovsky, Alexander§; Bouville, André**; Anspaugh, Lynn††; Voillequé, Paul‡‡; Luckyanov, Nickolas**
Reference: Health Phys. 86, 565-585 (2004)
Keywords: Chernobyl, thyroid, cancer, children
Abstract: Large amounts of radioiodines were released into the atmosphere during the accident at the Chernobyl nuclear power plant on 26 April 1986. In order to investigate whether the thyroid cancers observed among children in Belarus could have been caused by radiation exposures from the Chernobyl accident, a team of Belarusian, Russian, and American scientists conducted a case-control study to compare cases and controls according to estimated thyroid dose. The primary purpose of this paper is to present detailed information on the estimated thyroid doses, due to intakes of 131I, that were used in the case-control study. The range of the 131I thyroid doses among the 107 cases and the 214 controls was found to extend from 0.00002 to 4.3 Gy, with medians of approximately 0.2 Gy for the cases and 0.07 Gy for the controls. In addition, the thyroid doses resulting from the intakes of short-lived radioiodines (132I, 133I, and 135I) and radiotelluriums (131mTe and 132Te) were estimated and compared to the doses from 131I. The ratios of the estimated thyroid doses from the short-lived radionuclides and from 131I for the cases and the controls range from 0.003 to 0.1, with median values of approximately 0.02 for both cases and controls.
URL: http://journals.lww.com/health-physics/Abstract/2004/06000/INDIVIDUAL_THYROID_DOSE_ESTIMATION_FOR_A.2.aspx
Title: SPECIAL REPORTS Report by Prof. E.D. Williams, Cambridge University,… THYROID EFFECTS
Author: E.D. Williams, A. Pinchera, D. Becker, . E.P. Demidchik, S. Nagataki, N.D. Tronko,
Reference: [PDF-73K]Jul 2007 IAEA BULLETIN, 3/1996
Keywords:
Abstract: …Ukraine close to Chernobyl, received the…for childhood thyroid cancer in Gomel during…cally confirmed thyroid cancers in children…Ukraine since the Chernobyl acci- dent…cases of childhood thyroid cancer is needed. The…
URL: http://www.iaea.org/Publications/Magazines/Bulletin/Bull383/38305893132.pdf
Title: Overexpression of angiogenic growth factors, VEGF, PDGF, and bFGF in head and neck squamous cell carcinoma in the betel quid chewing prevalent area
Author: Chang, J.T. / Cheng, A.J. / Liao, C.T. / Wang, H.M. / Chen, I.H.
Reference: European Journal of Cancer, 37 (Supplement 6), p.S113, Apr 2001
doi: 10.1016/S0959-8049(01)80902-3
Keywords:
Abstract: …increases in the incidence of childhood thyroid cancer have occurred following the Chernobyl accident. Data from the Ukraine…radionuclides in the etiology of thyroid cancer. 498 Thyroid Carcinoma After Chernobyl D. Williams. University of Cambridge…
URL:http://www.sciencedirect.com/science/article/pii/S0959804901809023
Title: Social Aspects of the Chernobyl Activity in Belarus
Author: Mikhail V. MALKO
Reference: [PDF-75K]Aug 2002 Institute of Physical and Chemical Radiation Problems of the National Academy of Sciences of Belarus.
Keywords:Belarus
Abstract: The Chernobyl accident has caused heavy impact on the environment in Belarus, Russia and the Ukraine. It has also resulted in a significant worsening of the economic situation in the affected republics of the former USSR, as well as in disruption of social life in large territories, growing anxiety and fears among the people living in contaminated areas and significant medical effects on all categories of the people affected by the accident. The USSR authorities knew about the seriousness of the radiological situation caused by the Chernobyl accident from the very beginning. However, at the time of the accident, the Soviet Union was in a state of deep economic crisis and was unable to implement necessary measures to mitigate the radiological consequences of the accident. That was one of the reasons for the USSR to conceal the true information about the accident and its consequences from the Soviet people. The traditional Soviet policy of concealing all data on any unpleasant event happening in the Soviet Union had played a very important role too. The collapse of the USSR created the formal possibility to develop appropriate policy aimed at mitigation of the Chernobyl consequences in Belarus, Russia and the Ukraine. However, implementation of this policy has been limited due to lack of necessary material and financial means. These and other problems are the subject of the present report.
URL: http://www.rri.kyoto-u.ac.jp/NSRG/reports/kr21/kr21pdf/Malko3.pdf
Title: Inhibitory effect of sulindac and sulindac sulfone (Exisulind)on tumour growth and angiogenesis
Author: Rogala, E. / Skopinska-Rozewska, E. / Skurzak, H. / Sommer, E. / Bialas-Chromiec, B. / Filewska, M. / Thompson, W.J. / Pamukcu, R.
Reference: European Journal of Cancer, 37 (Supplement 6), p.S113, Apr 2001
doi: 10.1016/S0959-8049(01)80903-5
Keywords:
Abstract: …increases in the incidence of childhood thyroid cancer have occurred following the Chernobyl accident. Data from the Ukraine…radionuclides in the etiology of thyroid cancer. 498 Thyroid Carcinoma After Chernobyl D. Williams. University of Cambridge…
URL: http://www.sciencedirect.com/science/article/pii/S0959804901809035
Title: Prophylactic Central Neck Dissection in Stage N0 Papillary Thyroid Carcinoma
Author: Sergio Zuniga, Alvaro Sanabria,
Reference: [PDF-158K] Apr 2012 Arch Otolaryngol Head Neck Surg. 2009;135(11):1087-1091.
doi: 10.1001/archoto.2009.163
Keywords:
Abstract: Thyroid carcinoma is the most frequent neoplasm in the head and neck. The incidence of thyroid carcinoma has been increasing progressively in the last few years, primarily owing to early diagnosis facilitated by the wide use of ultrasonography.1 In addition, the incidence has increased as the result of high exposure to radiation, such as occurred after the Chernobyl accident.2 Moreover, a change in histologic type has been demonstrated, with a decrease in the number of undifferentiated tumors and an increase in the number of papillary tumors, as well as a change in the size of tumors detected. Previously, most clinically detected tumors were nodules of more than 4 cm. More recently, imaging examinations have found an increasing number of nodules smaller than 2 cm in diameter, but their earlier detection has not had any effect on long-term survival.1
URL: http://archotol.jamanetwork.com/article.aspx?articleid=410638
Title: Projected global health impacts from severe nuclear accidents: Conversion of projected doses to risks on a global scale: Experience from Chernobyl releases
Author: Catlin, R.J. / Goldman, M. / Anspaugh, L.R.
Reference: Lawrence Livemore National Laboratory Jan 1987
Keywords:
Abstract: Best estimates of possible additional health effects were projected for the Northern Hemisphere: (1) over the next 50 years, up to 28 thousand radiation-induced fatal cancers, compared to an expected 600 million cancer deaths from natural or spontaneous causes; (2) over the next year, up to 700 additional cases of severe mental retardation, compared to a normal expectation of 340 thousand cases; and (3) in the first generation, up to 1.9 thousand radiation-induced genetic disorders, compared to 180 million naturally-occurring cases. The possibility of zero health effects at very low doses and dose rates cannot be excluded. Due to the very large numbers of naturally-occurring health effects, it is unlikely that any additional health effects will be demonstrable except, perhaps, for the more highly exposed population in the immediate vicinity of Chernobyl. 13 refs., 4 figs., 6 tabs.
…arising from Chernobyl releases has…collective dose to the thyroid, no corrections…effects due to the Chernobyl
accident. In…expected 600 million cancer deaths from natural…in collective thyroid dose over the…following the Chernobyl accident. A…Projections of cancer risks, both…
URL: http://www.osti.gov/bridge/product.biblio.jsp?query_id=2&page=0&osti_id=5720088
Title: General Situation of the Radiological Consequences of the Chernobyl Accident in Ukraine
Author: Dmytro M. GRODZINSKY
Reference: [PDF-85K]Oct 2002 Institute of Cell Biology and Genetic Engineering, National Academy of Sciences of Ukraine
Keywords:
Abstract: …medical consequences of the Chernobyl accident. Opinions differ…Ukrainian population after the Chernobyl accident. There are many supporters…consequences of iodine influence on thyroid gland. I would like to note…diminish the consequences of the Chernobyl accident or even treat it…
URL: http://www.rri.kyoto-u.ac.jp/NSRG/reports/kr21/kr21pdf/Grodzinsky.pdf