Dynamics of thyroid cancer incidence in Russia following the Chernobyl accident: eco-epidemiological analysis
Title: Dynamics of thyroid cancer incidence in Russia following the Chernobyl accident: eco-epidemiological analysis Medical Radiological Research Center of RAMS, Obninsk
Author: Ivanov V.K., Tsyb A.F., Gorsky A.I., Maksioutov M.A.
Reference: SCIENTIFIC ARTICLES [PDF-172K]Apr 2001
Keywords:
Abstract: The paper presents the analysis of thyroid cancer incidence in the territories of Russia that were most contaminated after the Chernobyl accident. Incidence data in the Bryansk, Kaluga, Orel and Tula regions (5,298 thousand persons) are used. Information on incidence has been obtained from regional oncological dispensaries (state health institutions involved in diagnosis and treatment of malignant neoplasms). Altogether, 2,599 cases of thyroid cancer are considered from 1982 to 1995. Of them, 62 cases were among children and adolescents and 143 among the population who were children and adolescents at the time of the accident in 1986. The study is performed for both sexes. The study compares the distribution of thyroid cancer cases by age at diagnosis and age at exposure. It has been shown that since 1991 the age structure of the incidence has changed significantly with the growing proportion of cases among children and adolescents. The change in the structure occurred due to the radiation factor, specifically as a result of exposure of thyroid to incorporated 131I. A dependence of risk of cancer on age at exposure has been derived. For children of 0-4 years at exposure the risk of induction of radiogenic thyroid cancer is 6-10 times higher than in adults. On the average, the risk co-efficient in children and adolescents at the time of exposure is about 3 times higher than that in adults. The analysis of time trend in thyroid cancer incidence has shown that the incidence rate observed in the period from 1991 to 1995 in the age groups up to 25 years is expected to be maintained in the near future.
URL: http://users.physics.harvard.edu/~wilson/radiation/rr11-12/chapter1.pdf
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