カテゴリー「cancer」
Author: Biryukov, Aleksandr Petrovich
Reference: Abstract of thesis for the degree of Doctor of Medical Sciences Obninsk – 2009
Keywords: National Radiation and Epidemiological Registry
Abstract: Development of the complex of medical and organizational support provided by NRER, execution, on its base, of large-scale epidemiological studies of the population affected by radiation contamination after the accident at the Chernobyl nuclear power plant in Russia, and evaluation of the possibility of carcinogenic effects of X-ray diagnostic studies.
URL: http://earthpapers.net/mediko-organizatsionnoe-obespechenie-natsionalnogo-radiatsionno-epidemiologicheskogo-registra-rossii
Title: The dose and the risks from water use by people of South-Western Bryansk region
Author: Katkova Margarita Nikolaevna
Reference: Radioation and Lisk 2008 vol.17 No.1
Keywords: dose exposure, Water use, risk, radionuclides of 90Sr and 137Cs, Chernobyl accident
Abstract: In the present work the estimation of risk for the population of southwest areas of Bryansk region exposed to radiation fallout after Chernobyl accident is carried out. The life risk of disease for the population of the specified areas is estimated by a cancer through a dose received from water use. The basic ways of radionuclide receipt in an organism of inhabitants of southwest areas of Bryansk region on a water chain are: an external exposure from polluted flood-land of water body, consumption of water from the sources of the drinking water supply located in the polluted zone, and consumption of fish caught from a local water body. As object of research the population living in area of Lake Kozhanovskoe is accepted. The contribution of radionuclides o f9 Sr and 137Cs in a total dose from water use is estimated. Priority sources of risk for the population from water use to which it is necessary to pay special attention at carrying out of protective actions in the specified territories are revealed.
URL: http://cyberleninka.ru/article/n/dozy-i-riski-ot-vodopolzovaniya-poluchaemye-naseleniem-yugo-zapadnyh-rayonov-bryanskoy-oblasti
Title: Cancer incidence among the participants of the liquidation of the consequences of the Chernobyl disaster
Author: Ivanov V.K., Rastopchin E.M., Gorskiy A.I., Ryvkin V.B.
Reference: Radioation and Lisk 1996 No.8
Keywords:incidence, liquidators
Abstract: The work presents data on incidence of solid malignant neoplasms among liquidators of the Chernobyl accident which have been gathered in Russian National Medical and Dosimetric Registry from 1986 to the beginning of 1996. RNMDR contains individual dosimetric data and results of annual medical check-ups of the liquidators living on the territory of Russia. The study involves male liquidators who had no oncological diseases before arrival to the 30-km zone and for whom the following information was available: confirmed dose of external irradiation, birth date, date of arrival to the 30-km zone, time spent in the 30-km zone, results of medical checkups. The number of liquidators under study was 114504 persons, which is about 68% of all liquidators registered in RNMDR. The average dose of the considered cohort is 108 mGy, the average age at the time of their first arrival to the 30-km zone is 34.3 year and the total number of person-years spent in the zone is 797781. The liquidatorsx27; cohort is briefly characterized, cancer incidence of liquidators is compared with that of the population of Russia as a whole by calculating standardized incidence ratio (SIR). SIRs with 95% confidence intervals for all solid malignant neoplasms and cancers of the digestive system were 1.23 (1.15; 1.31) and 1.11 (1.01; 1.24) respectively. Estimation of radiation risks for the same disease classes has revealed a statistically significant increase in cancer incidence with increase in external radiation dose of liquidators.
URL: http://cyberleninka.ru/article/n/onkologicheskaya-zabolevaemost-sredi-uchastnikov-likvidatsii-posledstviy-chernobylskoy-katastrofy
Reference: Радиация и риск (Radiation and risk): 1996, no. S1
Abstract: Instructions for the completion of the registry card of cancer diseases of persons exposed to radiation due to the Chernobyl accident.
URL: http://cyberleninka.ru/article/n/prilozhenie-3-k-prikazu-minzdravmedproma-rossii-236-ot-11-avgusta-1995-g-registratsionnaya-karta-onkologicheskogo-zabolevaniya-litsa
Title: RISK ESTIMATION OF RADIATION MEDICAL EXPOSURE IN TERMS OF EFFECTIVE DOSES
Author: IVANOV V.K., KASCHEEV V.V., CHEKIN S.YU., MENYAYLO A.N., PRYAHIN E.A., TSYB A.F., METLER F.A.
Reference: Radiation and Lisk 2012 vol.21 No.4
Keywords: RADIATION RISKS, COMPUTED TOMOGRAPHY, ORGAN AND EFFECTIVE DOSES, LIFETIME ATTRIBUTABLE RISK
Abstract: The authors compare values of radiation risks of potential cancer from diagnostic radiation exposure assessed with the use of organ and effective doses. Estimates of lifetime attributable risk from CT scanning made with ICRP 103 risk models and national data of medical statistics are given as an example. It is shown that values of lifetime attributable risk based on organ and effective doses can differ 3.11 times. Values of lifetime attributable cancer risk for specific organs are presented as well.
URL: http://cyberleninka.ru/article/n/otsenka-radiatsionnogo-riska-meditsinskogo-oblucheniya-v-terminah-effektivnoy-i-organnyh-doz
Title: Individual assessment of radiation risks for different scenarios of professional chronic exposure
Author: Ivanov V.K., Kaydalov O.V., Kascheeva P.V., Korelo A.M., Panfilov A.P., Vasilenko E.K.
Reference: Radiation and Lisk 2008 vol.17 No.2
Abstract: New “dose matrix” approach used for optimization of radiation protection of a personnel is examined. Values of radiation risks calculated for different occupational radiation exposure scenarios are given. Potential enhanced risk group among workers of the Industrial Association Mayak, who are under permanent dosimetry monitoring, is formed on the basis of dosimetric information and existing standards of radiation protection.
Keywords: technological platform of radiation protection, “dose matrix”, radiation risk among workers of the Industrial Association Mayak
URL: http://cyberleninka.ru/article/n/otsenka-individualnyh-radiatsionnyh-riskov-pri-razlichnyh-stsenariyah-professionalnogo-hronicheskogo-oblucheniya
Title: Individual risk from occupational exposure for nuclear industry workers
Author: Ivanov V.K., Tsyb A.F., Panfilov A.P., Agapov A.M., Kaydalov O.V., Korelo A.M., Maksyutov M.A., Chekin S.YU., Kascheeva P.V., Saenko A.S.
Reference:Radiation and Lisk 2008 vol.17 No.3
Keywords: individual radiation risk, “dose matrix”, nuclear industry workers, chronic occupational exposure
Abstract: Internationally, the upper limit of acceptable individual risk from occupational exposure for nuclear industry workers is determined by the death probability 10-3 year-1. The same risk value of 10-3 year-1 is established by the Radiation Safety Standards currently in force in Russia. The United Nations Scientific Committee on the Effects of Atomic Radiation has proposed the formulae for estimating individual risk of developing cancer with allowance for radiation dose, age at exposure, attained age and sex. This methodology is first applied to estimate individual radiation risk for nuclear industry workers (49900 persons) who were monitored for radiation exposure through the use of personal dosimeters. The estimates show that in 2006 the threshold of 10-3 year-1 for individual risk is exceeded for 755 persons, which is 1.6 % of all workers covered by personal dose monitoring. The excess absolute risk (EAR) and attributive risk (AR) were estimated for all cancers, solid cancers and leukemias. The principles for forming potential risk groups are discussed.
URL: http://cyberleninka.ru/article/n/otsenka-individualnogo-radiatsionnogo-riska-pri-professionalnom-hronicheskom-obluchenii
Title: Analysis Of The incidence and mortality with respect to malignant neoplasms of the digestive system in the Chernobyl liquidators 1986-1997
Author: Biryukov A.P., Ivanova I.N., Gorskiy A.I, Petrov A.V., Matyash V.A.
Reference: Radiation and Lisk 2001 No.12
Keywords:
Abstract: The paper provides analysis of information about incidence and mortality with respect to malignant neoplasms of the digestive system in the Chernobyl liquidators accumulated in the Russian National Medical and Dosimetric Registry (RNMDR) in the period from 1986 to the beginning of 1998. The study includes male liquidators registered in six regional centers of the RNMDR providing most reliable medical and dosimetric data on an annual basis, namely Northwest, Volgo-Vyatsky, Central-Chernozemny, Povolzhsky, North-Caucasian and Urals. The number of liquidators under study is 96026 persons, which accounts for 57% of all liquidators registered in the RNMDR. The mean dose in the study cohort is 108 mGy, the mean age at the time of entry in the zone is 34.3 years and the total accumulated number of person-years is 1011727. The incidence and mortality rates for cancers of the digestive system were compared for liquidators and the population of Russia in general through calculation of the standardized incidence ratio (SIR) and the standardized mortality ratio (SMR). The values of SIR and SMR with 95% confidence intervals (CI) for malignant neoplasms of the digestive system were estimated to be 0.88 (0.80; 0.97) and 0.72 (0.64; 0.80), respectively. For liquidators who arrived in the zone in 1986 these are 0.97 (0.85; 1.11) and 0.81 (0.70; 0.94), respectively. During the period of 1991-1997, when SIR in liquidators became stable, the values of SIR and SMR with 95% CI for malignant neoplasms of the digestive system were 1.00 (0.90; 1.10) and 0.87 (0.78; 0.98), respectively. For liquidators who arrived in the zone in 1986 these values were 1.15 (1.00; 1.33) and 1.02 (0.86; 1.19), respectively. Estimation of radiation risks for this class of diseases did not reveal any statistically significant increase in cancer incidence or mortality with increase in external radiation dose in liquidators.
URL: http://cyberleninka.ru/article/n/analiz-zabolevaemosti-i-smertnosti-ot-zlokachestvennyh-novoobrazovaniy-pischevaritelnoy-sistemy-sredi-likvidatorov-za-1986-1997-gody
Title: Radiation oncology in Russia after the Chernobyl accident: forecast and actual data
Author: Ivanov V.K., Remennik L.V., Tsyb A.F., Starinskiy V.V., Chissov V.I., Maksyutov M.A., Mokina V.D., Gorskiy A.I., Harchenko N.V., Gretsova V.I., Scheplyagina L.A., Petrova G.V., Chekin S.YU., Nilova E.V., Rubtsova M.M., Efendiev V.A., Leshakov S.YU., Shiryaev V.I., Pochtennaya G.T., Proshin A.D., Kvitko B.I.
Reference: Radiation and Lisk 1995 No.6
Abstract: This work presents results of complex studying the morbidity and mortality from malignant neoplasms on the territories of Bryansk, Kaluga, Orel and Ryazan oblasts most radiocontami-nated after the ChNPP accident. Complexity of the approach was provided by solving the three basic tasks: assessment of possible contribution of radiation factor into oncomorbidity, i.e. prognostication of mortality and morbidity conditioned by radiogenic cancers; analyzing the development of oncoepidemiological situation (dynamics of morbidity indices) during the period from 1981 till 1994; assessment of relative risks of arising malignant neoplasms among population of indicated oblasts as compared to Russia before and after the ChNPP accident. Calculations models and risk coefficients recommended by the International Commission on Radiological Protection (ICRP) and the Committee on Biological Effects of Ionizing Radiation of USA (BEIR-V) as well as medico-demographic and dosimetric data on studied regions are used in the prognostication. In consequence of the prognostication the life attributive risk for the majority of oncodiseases was demonstrated not to exceed 5%, except thyroid cancer for which the attributive risk is expected to peak in Bryansk oblast and to reach 18-20% for adults and 45-50% for children. By this is meant that each fifth thyroid cancer among adults and each second cancer among children will be radiation-induced. Analysis of risks and oncomorbidity indices among residents of contaminated territories before and after the accident allows to conclude that the forming the levels of oncomorbidity available at present, their structure and dynamics occurred primarily under influence of factors existing before the accident. As a result of the analysis of all three aspects of given problem the conclusion about the lack of statistically reliable effect of radiation factor on oncomorbidity is made. Levels of onco-morbidity and oncomortality in contaminated regions reflect mainly the common tendency of changing these indices on Russia as a whole. The conclusion made is generally in agreement with the data of world practice on latent periods of induction of radiogenic cancers and values of radiation effects for levels of irradiation to which the population living on contaminated territories is exposed.
URL: http://cyberleninka.ru/article/n/radiatsionnaya-onkoepidemiologiya-v-rossii-posle-chernobylskoy-katastrofy-prognoz-i-fakticheskie-dannye
Title: Population patterns of oncopathology in the population living in contaminated areas after the Chernobyl accident
Author: Parshkov E.M., Sokolov V.A., Golivets T.P., Kovalenko B.S., Artamonova YU.Z.
Reference: Radiation and Lisk 2009 vol.18 No.3
Keywords: Chernobyl accident, oncology, Population Incidence, descriptive epidemiological analysis, Mechanisms of carcinogenesis, Belgorod and Bryansk Regions
Abstract: Descriptive epidemiological analysis of more than 200 thousands of new cancer cases over 25-year period (1981-2005) among population of the Belgorod and Bryansk Regions affected as a result of the Chernobyl accident was carried out. Age-gender dependencies of population oncopathology development during this period as well as the dynamics the incidence changes in separate nosological units were determined. It was shown that exposure in low dose after the Chernobyl accident led to wavy change of the incidence with the period 5-7 years and that radiation-induced incidence developed in the format of spontaneous one. The role of physiological factors of organism and processes of cell proliferation and differentiation in cancer development are discussed.
URL: http://cyberleninka.ru/article/n/polovozrastnye-zakonomernosti-razvitiya-onkopatologii-u-naseleniya-prozhivayuschego-na-zagryaznennyh-territoriyah-posle
