カテゴリー「neurology」
Author: K.N. Loganovsky, S.A. Chumak, M.A. Bomko
Reference: Экстренная медицина (Emergency Medicine), 2012
Keywords: neuropsychiatric disorders, rehabilitation, society
Abstract: Based on the analysis and synthesis of the results of our prospective study of neuropsychiatric disorders in victims of the Chernobyl disaster, we developed a model of mental health and approaches to psycho-rehabilitation in the structure of preparedness for radiological emergencies. The mental health of the victims should be the focus of public attention regarding possible radiation accidents or radiological terrorist attacks in the future.
URL: http://www.recipe.by/izdaniya/periodika/medicina/archiv/em_02_2012/nauchnye_publikacii/1340100518.html
Author: Loganovsky K.N., Nechayev S.Yu., Perchuk I.V.
Reference: Український медичний часопис (Ukrainian Medical Magazine) , 2008
Keywords: uranium, transuranium elements, neurotoxicity, radiotoxicity, Shelter Object
Abstract: Physical-chemical properties, prevalence, using, and neuropsychiatric effects of uranium, including depleted uranium, and transuranium elements (mainly, plutonium and americium) are discussed in the article. It is shown the increasing role of these elements in connection with Chernobyl accident and the Shelter Object transformation to an ecologically safety system. In accordance to the recent data on neurotoxicity of uranium it is supposed the same toxicity for the transuranium elements. The neurophysiological examinations of the Shelter Object personnel have revealed the disorders of cerebral bioelectrical activity to be the basis for neuropsychiatric pathology development. Exposure to low and very low doses of ionizing radiation, neurotoxicity of uranium and transuranium elements, stress, as well as other non-radiation industrial hazards were assumed to be proposed as the possible risk factors. The study of biological effects of uranium and transuranium elements are crucial for radiobiology, radiation hygiene and neuropsychiatry. It is necessary to conduct large-scale studies in this field. The Shelter Object transformation to an ecologically safety system is the unique possibility to study of radiotoxical effects of uranium and transuranium elements on the human body. (full text available on web)
URL: http://www.umj.com.ua/wp-content/uploads/archive/64/pdf/31_rus.pdf?upload
Author: K.N. Loganovsky, A.N. Kovalenko, N.V. Denisyuk
Reference: Кровообіг та гемостаз (Circulation and hemostasis), 2010
Keywords:
Abstract: Angioneurological features of chronic cerebrovascular disease, in the remote period after total body irradiation in the dose range 0,025-4,7 Sv, are confirmed. As model target, a left internal carotid artery is adopted. Etiological heterogeneity changes of cerebral hemodynamics, in the remote period after irradiation, is confirmed, at which the role of radiation, among traditional risk factors (age, somatic diseases, smoking, alcohol abuse), is shown in doses exceeding 0.3 Sv.
URL: http://library.zsmu.edu.ua/CGI/irbis64r_91_opac/cgiirbis_64.exe?LNG=&C21COM=S&I21DBN=ZSMUL&P21DBN=ZSMUL&S21FMT=infow_wh&S21ALL=(%3C.%3EA%3D%D0%9B%D0%BE%D0%B3%D0%B0%D0%BD%D0%BE%D0%B2%D1%81%D0%BA%D0%B8%D0%B9,%20%D0%9A.%20%D0%9D.$%3C.%3E)&Z21ID=&S21SRW=TIPVID&S21SRD=DOWN&S21STN=1&S21REF=10&S21CNR=20
Author: K.N. Loganovsky, M.A. Bomko, S.A. Chumak
Reference: Психиатрия, психотерапия и клиническая психология (Psychiatry, psychotherapy and clinical psychology), 2012
Keywords: cerebrovascular disease, organic mental disorders, depression, neurotic stress-related and somatoform disorders, protection measures
Abstract: In the victims of the Chernobyl disaster, especially the liquidators, revealed an excess of cerebrovascular disease, organic mental disorders, depression, neurotic, stress-related and somatoform disorders and alcohol dependence. Progredient character of the flow of the disease is confirmed. We have developed models for mental health care in radiation accidents and radiological terrorist attacks, differentiated algorithms of the provision of neuropsychiatric intensive care, in the structure of medical response in such events, and block model for neuropsychiatric intensive assistance for victims of radiological emergencies.
URL:http://www.recipe.by/izdaniya/periodika/psihiatriya/archiv/ppkp_2_2012/Original/1339967617.html
Author: K.N. Loganovsky
Reference: Укр. мед. часопис. (Ukrainian Medical Magazine), 1998
Abstract: A well known article on the subject, yet without details on the web. For detailed information on the article contact the National Scientific Center for Radiation Medicine of Ukraine. The center’s home page is: http://www.national.rcrm.net.ua/index.php/en/
Author: K.N. Loganovsky
Reference: Новая медицина тысячелетия (New Medicine of the Millennium), 2010
Abstract: the article introduces the history of atomic neuropsychiatry. Full text in Russian on the web magazine, on pages 16-27.
URL: http://nmt-journal.com/arch/files/full/2010_3.pdf
Author: K.N. Loganovsky
Reference: Журн. невропатол. и психиатр. им. С.С. Корсакова. (journal of neuropathology and psychiatry named after S.S. Korsakov), 2000
Keywords:
Abstract: Neurological, psychiatric and psycho-physiological (computer EEG) surveys were conducted on 100 victims of the Chernobyl disaster, in whom acute radiation syndrome (ARS) was diagnosed in 1986, 100 employees of the Chernobyl exclusion zone, who volunteered to work in the area from 1986-1987 for 5 years or more, as well as group of comparisons (control group) with 20 healthy individuals, 50 veterans of the war in Afghanistan with effects of post-traumatic stress disorder (PTSD) and 50 veterans with effects of PTSD and mild closed head injury. In remote period of exposure, left hemisphere cortico-limbic and diencephalic-right-brain syndromes were detected. Schizophrenia and other pathologies are observed.
URL: http://nature.web.ru/db/msg.html?mid=1174807&uri=index.html
Author: K.N. Loganovsky
Reference: Український медичний часопис (Ukrainian Medical Magazine), 2009
Keywords: ionizing radiation, low doses, Chernobyl accident, brain, radiosensitivity, radiocerebral effects, exposure in utero.
Abstract: The aim is to analyze the current evidences on radiocerebral effects following exposure to 20 mSv on fetus and >300 mSv on thyroid in utero; 16–25 weeks — >10 mSv and >200 mSv, respectively. A life span study should be done for the cohort of prenatally irradiated persons as a result of the Chernobyl accident,as well as those exposed at the age of 0–1 years. These survivors are under increased risk of different neuropsychiatric disorders, including schizophrenia. Radiation exposure in childhood is obviously associated with dose-related cognitive decline in adulthood and neuropsychiatric disorders, including schizophrenia, later in life. The possible dose thresholds of delayed radiation brain damage are the doses as low as 0.1–1.3 Gy on the brain in childhood. In adults, the radiation-associated cerebrovascular effects were obtained at >0.15–0.25 Sv. Dose-related neuropsychiatric, neurophysiological, neuropsychological, and neuroimaging abnormalities following exposure to >0.3 Sv, neurophysiological and neuroimaging radiation markers at doses >1 Sv were revealed. Postradiation brain damage is predominantly localized in the frontal-temporal areas of the left hemisphere and involves both white and gray matter of the brain. The cerebral structural and functional abnormalities after irradiation are characteristic as frontal and temporal cortex atrophy, changes of subcortical structures and neuronal pathways, mainly in the dominant hemisphere. Adulthood radiation exposure is the risk factor for the Chronic Fatigue Syndrome as the predisposition for neurodegeneration, cognitive deficit and other neuropsychiatric disorders development, accelerating CNS ageing, as well as the new model of schizophrenia. Studies on radiation neuropsychiatric effects should be realized.
URL: http://www.umj.com.ua/wp-content/uploads/archive/71/pdf/1440_rus.pdf?upload
Title: Risk factors for long-term mental and psychosomatic distress in Latvian Chernobyl liquidators
Author: J F Viel, E Curbakova, B Dzerve, M Eglite, T Zvagule, and C Vincent
Reference: Environ Health Perspect. 1997 December; 105(Suppl 6): 1539–1544.
Keywords: Risk factors, mental distress, psychosomatic disorders, Latvia, liquidators
Abstract: Epidemiologic studies on the health effects of the Chernobyl disaster have focused largely on physical health, whereas the psychological consequences have received little attention. The authors have assessed the associations of various exposure variables with mental and psychosomatic distress in a sample of 1412 Latvian liquidators drawn from the State Latvian Chernobyl Clean-up Workers Registry.
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469928/
Title: Two-year follow up study of stress-related disorders among immigrants to Israel from the Chernobyl area.
Author: J Cwikel, A Abdelgani, J R Goldsmith, M Quastel, and I I Yevelson
Reference: Environ Health Perspect. 1997 December; 105(Suppl 6): 1545–1550.
Keywords: stress disorders, immigrants (from Chernobyl-affected areas), Israel
Abstract: [We report on findings from a 2-year follow-up study of immigrants originating from exposed areas around the site of the 1986 Chernobyl accident matched with comparison subjects emigrating from other republics in the Confederation of Independent States. In the initial study of 708 immigrants, the samples were matched by age, gender, and year of immigration. We assessed two exposure groups–high and low–by estimating levels of ground cesium contamination from the International Atomic Energy Agency maps. We reinterviewed 520 immigrants from the first wave of data collection (a reinterview rate of 73%), 87 from high-exposure areas, 217 from low-exposure areas, and 216 comparison subjects. This study examined the prevalence of symptoms of posttraumatic stress disorders (PTSD), depression, somatization, anxiety, and physical effects (high blood pressure, acute symptoms, and chronic illness)…]
URL:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469946/
