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カテゴリー「thyroid cancer」

Chernobyl and hypothyroidism

Title: Chernobyl and hypothyroidism

Author: Mangano, Joseph J

Reference: The Lancet, 348 (9025), p.476-477, Aug 1996

doi: 10.1016/S0140-6736(05)64571-0

Keywords:

Abstract: …and for why thyroid cancer in Belarus and…years after the Chernobyl incident. For…known that excess thyroid cancer from therapeutic…isotopes in the Chernobyl fallout may provide…surprising patterns of thyroid cancer and hypothyroidism…

URL: http://www.sciencedirect.com/science/article/pii/S0140673605645710

The seven projects and their achievements in 5 years that provide new post-COE concepts

Title: The seven projects and their achievements in 5 years that provide new post-COE concepts

Author: Tomonaga, Masao

Reference: International Congress Series, 1299, p.3-9, Feb 2007

doi: 10.1016/j.ics.2006.09.018

Keywords: COE project; Epidemiology; Molecular epidemiology; Stem cell theory; Regenerative medicine

Abstract: During the actuarial period of 4 years spent on our COE Program, we have conducted seven major projects: high quality medical care and epidemiology of radiation exposed victims in Nagasaki, Chernobyl and Semipalatinsk, molecular epidemiology of radiation-induced cancers, basic radiation biology in terms of low-dose effect on human cells and carcinogenesis, promotion of international preparedness for acute radiation accident and practical regeneration medicine for acute radiation injuries and international exchange of young investigators and development of e-learning system on radiation life science. These activities brought about an important finding that thyroid cancer in Chernobyl and solid cancers and hematopoietic neoplasia in atomic bomb survivors continued over 20 years and 60 years, respectively. This finding provides stem cell target theory to explain the life-long effect of radiation on the human body. Therefore, our post-COE concept should be how to prove this hypothesis and develop improved medical care for radiation victims including prevention and early detection of cancers.

URL:http://www.sciencedirect.com/science/article/pii/S0531513106006273

UNSCEAR 2008 Report to the General Assembly with Scientific Annexes Volume II, Annex D: Health effects due to radiation from the Chernobyl accident (Advance copy)

Title: UNSCEAR 2008 Report to the General Assembly with Scientific Annexes Volume II, Annex D: Health effects due to radiation from the Chernobyl accident (Advance copy)

Reference: SOURCES AND EFFECTS OF IONIZING RADIATION UNSCEAR 2008  [PDF-6MB]Apr 2011

Keywords:

Abstract:… In the former Soviet Union, the contamination of fresh milk with 131I and the lack of prompt countermeasures led to high thyroid doses, particularly among children. In the longer term, mainly due to radiocaesium, the general population was also exposed to radiation externally from radioactive deposition and internally from consuming contaminated foodstuffs. However, in part because of the countermeasures taken, the resulting radiation doses were relatively low (the average additional dose in 1986–2005 in “contaminated areas”6 of the three republics was about equivalent to that from a computed tomography (CT) scan in medicine), and should not lead to substantial health effects in the general population that could be attributed to radiation exposure from the accident. Even so, the severe disruption caused by the accident, confounded with the remarkable political changes that took place in the Soviet Union and the new republics, resulted in major social and economic impact, and great distress for the affected populations….

URL: http://inst.nuc.berkeley.edu/NE104/Radiation%20Risks/Advance_copy_Annex_D_Chernobyl_Report.pdf

In the shadow of Chernobyl—a report of the first international conference of the European Commission, Belarus, Russian federation and Ukraine on the radiological consequences of the Chernobyl accident, 18–22 march 1996, Minsk, Belarus

 

Title: In the shadow of Chernobyl—a report of the first international conference of the European Commission, Belarus, Russian federation and Ukraine on the radiological consequences of the Chernobyl accident, 18–22 march 1996, Minsk, Belarus

Author: Storm, H.H.

Reference: European Journal of Cancer, 32 (11), p.1864-1865, Oct 1996

doi: 10.1016/0959-8049(96)00159-1

Keywords:

Abstract: …is the highly increased risk of thyroid cancer in children and young adults…surprise is not the occurrence of thyroid cancer (from radioactive iodine…of the accident will contract thyroid cancer during the next 50 years. Psychological…

URL: http://www.sciencedirect.com/science/article/pii/0959804996001591

The toll of Chernobyl – scientific data wanted

Title: The toll of Chernobyl – scientific data wanted

Author: Habeck, Martina

Reference: The Lancet Oncology, 1 (Supplement 1), p.5, May 2000

doi: 10.1016/S1470-2045(09)70270-0

Keywords:

Abstract: …Panos Since the Chernobyl disaster 14 years…thousand cases of thyroid cancer have been diagnosed…lymphoma and thyroid cancer among the people…in cleaning up Chernobyl after the disaster…study concerning thyroid cancer in children…

URL:http://www.sciencedirect.com/science/article/pii/S1470204509702700

U.S./Belarus/Ukraine joint research on the biomedical effects of the Chernobyl Reactor Accident. Final report

Title: U.S./Belarus/Ukraine joint research on the biomedical effects of the Chernobyl Reactor Accident. Final report

Author: Bruce Wachholz

Reference: Other Information: PBD: 20 Jun 2000
doi: 10.2172/760446

Keywords: children, cohort,cleanup workers

Abstract: The National Cancer Institute has negotiated with the governments of Belarus and Ukraine (Ministers/Ministries of Health, institutions and scientists) to develop scientific research protocols to study the effects of radioactive iodine released by the Chernobyl accident upon thyroid anatomy and function in defined cohorts of persons under the age of 19 years at the time of the accident. These studies include prospective long term medical follow-up of the cohort and the reconstruction of the radiation dose to each cohort subject’s thyroid. The protocol for the study in Belarus was signed by the US and Belorussian governments in May 1994 and the protocol for the study in Ukraine was signed by the US and Ukraine in May 1995. A second scientific research protocol also was negotiated with Ukraine to study the feasibility of a long term study to follow the development of leukemia and lymphoma among Ukrainian cleanup workers; this protocol was signed by the US and Ukraine in October 1996.

URL: http://www.osti.gov/bridge/product.biblio.jsp?query_id=2&page=0&osti_id=760446

THYROID RADIATION DOSE IN BRITAIN ARISING FROM THE CHERNOBYL ACCIDENT

 

Title: THYROID RADIATION DOSE IN BRITAIN ARISING FROM THE CHERNOBYL ACCIDENT

Author: Tucker, Anthony / Bowlt, Colin

Reference: The Lancet, 328 (8517), p.1220-1221, Nov 1986

doi: 10.1016/S0140-6736(86)92229-4

Keywords:

Abstract: …radioiodine in the human thyroid? , Greatest concern…did they differ in thyroid status, mass, and…that the handful of thyroid cancers arising from Chernobyl radioiodine can be…buried within annual cancer figures. **This…

URL: http://www.sciencedirect.com/science/article/pii/S0140673686922294

Proliferative Activity of Human Thyroid Cells in Various Age Groups and Its Correlation with the Risk of Thyroid

Title: Proliferative Activity of Human Thyroid Cells in Various Age Groups and Its Correlation with the Risk of Thyroid

Cancer after Radiation Exposure

Author: Ali G. Saad, Seena Kumar, Elaine Ron, Jay H. Lubin, Jerzy Stanek, Kevin E. Bove, Yuri E. Nikiforov

Reference: [PDF-275K]Jun 2009 The Journal of Clinical Endocrinology & Metabolism 91(7):2672–2677
Keywords:

Abstract: …result of the Chernobyl accident exhibited…elevated risk of thyroid cancer (10 –12…age the risk of thyroid cancer was no longer…exposed after the Chernobyl accident, the incidence of thyroid cancer also was inversely…

URL: http://path.upmc.edu/people/ynlab/Publication%20PDFs/Saad2006TheJournalofClinicalEndocrinologyandMetabolism.pdf

FEATURES One decade after Chernobyl: The basis for decisions A major international conference sums up the scientific understanding of the Chernobyl accident’s major consequences …

Title: FEATURES One decade after Chernobyl: The basis for decisions A major international conference sums up the scientific understanding of the Chernobyl accident’s major consequences …

Reference: [PDF-838K] Jul 2007

Keywords: children  diagnosis

Abstract: A highly significant increase in the incidence of thyroid cancer among those persons in the affected areas who were children in 1986 is the only clear evidence to date of a public health impact of radiation exposure caused by the Chernobyl accident. (In 1991, the report on the International Chernobyl Project had stated that “it is expected that there will be a radiogenic excess of thyroid cancer cases in the decades to come. This risk relates to thyroid doses received in the first months after the accident…” *.) This increase in incidence has been observed in Belarus and to a lesser extent in Ukraine and in the Russian Federation. The number of reported cases up to the end of 1995 is about 800 in children under 15 years old at the time of diagnosis; more than 400 of these cases were in Belarus. In most cases the diagnoses have been confirmed by international experts. …

URL: http://www.iaea.org/Publications/Magazines/Bulletin/Bull383/38304781423.pdf

100 Cancer incidence in the Republic of Belarus: from 1970 to 2030

Title: 100 Cancer incidence in the Republic of Belarus: from 1970 to 2030

Author: Veyalkin, I. / Averkin, Y.U. / Krasny, S.

Reference: European Journal of Cancer Supplements, 8 (5), p.26, Jun 2010

doi: 10.1016/S1359-6349(10)70908-3

Keywords:

Abstract: …level then. Thyroid cancer incidence…immediately after Chernobyl disaster…females. Thyroid cancer incidence…before-Chernobyl level in…level then. Thyroid cancer incidence…immediately after Chernobyl disaster…

URL: http://www.sciencedirect.com/science/article/pii/S1359634910709083

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