カテゴリー「thyroid cancer」
Title: National Academy of Clinical Biochemistry Guidelines for the Use of Tumor Markers in Differentiated Epithelial Thyroid Carcinom
タイトル：
Author: Kenneth B. Ain, Ronald J Whitley
Reference: NACB: Practice Guidelines And Recommendations For Use Of Tumor Markers In The Clinic Thyroid Cancer (Section 3O) [PDF-83K]Feb 2008
Keywords: thyroid carcinoma, follicular, papillary, thyroglobulin
Abstract: …North America, thyroid cancer shows the greatest…increasing rate of cancer mortality in American…nuclear reactor in Chernobyl, Belarus, in 1986…environmental influences. Thyroid carcinomas, mostly…presentation for thyroid cancer is as a painless…
URL: http://www.aacc.org/SiteCollectionDocuments/NACB/LMPG/tumor/chp3o_thyroid.pdf
Title: Cancer in the Ukraine, post-Chernobyl
Author: Prisyazhiuk, Anatoly / Pjatak, O.A. / Buzanov, V.A. / Reeves, GillianK. / Beral, Valerie
Reference: The Lancet, 338 (8778), p.1334-1335, Nov 1991
doi: 10.1016/0140-6736(91)92632-C
Abstract: …leukaemia and thyroid cancer does not follow…living near Chernobyl, the increases…increase in cancer has yet occurred…result of the Chernobyl accident. The collection of cancer incidence data…in respect of thyroid cancer in children…
URL: http://www.sciencedirect.com/science/article/pii/014067369192632C
Title: Comet assay on children’s leukocytes 8 years after the Chernobyl disaster
Author: Frenzilli, G / Lori, A / Panasiuk, G / Ferdeghini, M / Barale, R
Reference: Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 415 (1-2), p.151-158, Jul 1998
doi: 10.1016/S1383-5718(98)00060-6
Keywords: Single cell gel electrophoresis; Human leukocyte; DNA damage; Bleomycin; Adaptive response
Abstract…. The children come from the Gomel region, one of the areas most heavily radio-contaminated by the Chernobyl fallout. In addition, leukocytes were treated with a challenge dose of bleomycin (BLM, 1.5 μg/ml), to assess the presence of an adaptive response (AR) potentially resulting from chronic exposure to radionuclides. As controls, 13 children living in Pisa (Italy) were enrolled in the study. Children with thyroid cancer show higher (p<0.001) DNA damage than healthy ones.. …
URL: http://www.sciencedirect.com/science/article/pii/S1383571898000606
Title: Mechanisms of chromosomal rearrangements in solid tumors: The model of papillary thyroid carcinoma
Author: Gandhi, Manoj / Evdokimova, Viktoria / Nikiforov, Yuri E.
Reference: Molecular and Cellular Endocrinology, 321 (1), p.36-43, May 2010
doi: 10.1016/j.mce.2009.09.013
Keywords: Thyroid cancer; RET/PTC; Nuclear architecture; DNA repair
Abstract: …risk factor for thyroid cancer, especially for papillary…increased incidence of thyroid cancer has been documented…radiation after the Chernobyl nuclear disaster in…2006 ). Studied of thyroid cancer in various populations…
URL:http://www.sciencedirect.com/science/article/pii/S0303720709004961
Title: Medical consequences of the Chernobyl Nuclear Power Plant accident: experience of 15-year studies
Author: Bebeshko, Vladimir G / Bobyliova, Olga A
Reference: International Congress Series, 1234, p.267-279, May 2002
doi: 10.1016/S0531-5131(01)00616-1
Keywords: Chernobyl disaster; Health status; Long-term monitoring; Incidence; Prevalence
Abstract:… All population health indexes have negative dynamics and are dramatically worse in comparison to the same age of Ukrainian population. The incidence of all cancers in clean-up workers increased. Since 1995, all cancer incidence rates are higher in the population of Ukraine. The thyroid incidence rate in evacuees exceeds the national rate by five to six times. The priority tasks for the achievement of the goals of health protection for the people who suffered as a result of the Chernobyl catastrophe were determined.
URL:http://www.sciencedirect.com/science/article/pii/S0531513101006161
Title: Molecular rearrangements in papillary thyroid carcinomas
Author: Zitzelsberger, Horst / Bauer, Verena / Thomas, Gerry / Unger, Kristian
Reference: Clinica Chimica Acta, 411 (5-6), p.301-308, Mar 2010
doi: 10.1016/j.cca.2009.11.028
Keywords: Papillary thyroid carcinoma; Gene rearrangement; Chromosome aberrations; Genetic heterogeneity
Abstract: …post-Chernobyl papillary thyroid carcinomas some researchers…radiation-associated thyroid carcinomas. However…contrast to the post-Chernobyl tumours, radiation-associated thyroid tumours either originated…in sporadic thyroid cancer in children [40…
URL: http://www.sciencedirect.com/science/article/pii/S0009898109006172
Title: Iodine nutrition in the Chernobyl area before and after the nuclear accident
Author: VanMiddlesworth, Lester
Reference: International Congress Series, 1234, p.163-168, May 2002
doi: 10.1016/S0531-5131(01)00605-7
Keywords: Iodine; Goiter; Chernobyl; Thyroid
Abstract: Reports from 1950 to 1960 suggest that goiter was frequent in the Chernobyl area and vigorous efforts were undertaken to distribute iodine supplements. There resulted enthusiastic reports stating that endemic goiter was no longer a problem. During the 1970s, the distribution of iodized salt became undependable and by 1980, goiter incidence was reported to have increased. Four to ten years after the Chernobyl nuclear accident, severe iodine deficiency was unusual but goiter by ultrasound measurement was found in more than 35% of the children. Unusual thyroid cancer appeared and its prevalence continues to increase.
URL: http://www.sciencedirect.com/science/article/pii/S0531513101006057
Title: DNA damage evaluated by alkaline single cell gel electrophoresis (SCGE) in children of Chernobyl, 10 years after the disaster
Author: Frenzilli, G / Bosco, E / Antonelli, A / Panasiuk, G / Barale, R
Reference: Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 491 (1-2), p.139-149, Apr 2001
doi: 10.1016/S1383-5718(01)00136-X
Keywords: Single cell gel electrophoresis; Human leukocytes; DNA damage; Bleomycin; Clastogenic factors
Abstract: Using the alkaline single cell gel electrophoresis (Comet) assay, the extent of DNA damage was evaluated in leukocytes of 43 Belarussian children (16 healthy and 27 affected by thyroid cancer). Thirty-nine healthy children from Pisa (Italy) were enrolled in the study as controls. In addition to basal levels of DNA damage, leukocytes were treated in vitro with bleomycin (BLM), a radiomimetic drug, to evaluate a possible adaptive response in different groups of children….
URL: http://www.sciencedirect.com/science/article/pii/S138357180100136X
Title: How shall we manage the incidentally found thyroid nodule?
Author: Aspinall, Sebastian R. / Ong, Sarah G.S. / Wilson, Michael S.J. / Lennard, Thomas W.J.
Reference: The Surgeon, In Press, Corrected Proof,Jan 2013
doi: 10.1016/j.surge.2012.11.004
Keywords: Thyroid; Thyroid nodule; Thyroid neoplasm; Ultrasonography; Cytology
Abstract: …Table 1 Risk factors for thyroid cancer on history. Risk factor for thyroid cancer Previous head and neck irradiation Exposure to nuclear fallout e.g. from Chernobyl Family history of medullary thyroid carcinoma or multiple endocrine neoplasia…
URL: http://www.sciencedirect.com/science/article/pii/S1479666X12001230
Title: Chromosomal aberrations in thyroid follicular-cell neoplasia: in the search of novel oncogenes and tumour suppressor genes
Author: Zitzelsberger, Horst / Thomas, Gerry / Unger, Kristian
Reference: Molecular and Cellular Endocrinology, 321 (1), p.57-66, May 2010
doi: 10.1016/j.mce.2009.11.014
Keywords: Follicular-cell neoplasia; Tumour suppressor gene; Oncogene; FISH; Chromosome; Rearrangement; Copy number alteration; Next-generation sequencing;Array CGH; Array painting
Abstract: …than just thyroid cancer, the reader…from the Chernobyl accident…papillary thyroid cancer. A recent…in post-Chernobyl and sporadic…in post-Chernobyl cases (aged…childhood thyroid papillary…papillary cancer are not necessarily…
URL: http://www.sciencedirect.com/science/article/pii/S0303720709005796
