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Increased level of chromosomal aberrations in lymphocytes of Chernobyl liquidators 6–10 years after the accident

Title: Increased level of chromosomal aberrations in lymphocytes of Chernobyl liquidators 6–10 years after the accident

Author: Natalia Slozina, Elizaveta Neronova, Tatiana Kharchenko, Alexey Nikiforov

Reference: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, Volume 379, Issue 2, 6 October 1997, Pages 121–125

DOI:http://dx.doi.org/10.1016/S0027-5107(97)00113-9

Keywords: Chromosome aberration; Liquidator; Radiation; Micronucleus

Abstract: Chromosomal aberrations (CA) were used to investigate the level of cytogenetical damage in peripheral blood lymphocytes from the liquidators in a remote period (6–10 years) after the Chernobyl accident. There was a significantly higher frequency of chromosomal radiation markers (dicentrics and rings) in the peripheral lymphocytes of the liquidators than in the control subjects. No differences between these groups were demonstrated by the micronucleus (MN) test. Increased frequency of chromatid exchanges was associated with the smoking habits of the liquidators.

URLhttp://www.sciencedirect.com/science/article/pii/S0027510797001139

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