Kinase Expression and Chromosomal Rearrangements in Papillary Thyroid Cancer Tissues: Investigations at the Molecular and Microscopic Levels

Title: Kinase Expression and Chromosomal Rearrangements in Papillary Thyroid Cancer Tissues: Investigations at the Molecular and Microscopic Levels

Author: Weier, Heinz-Ulrich / Kwan, Johnson / Lu, Chun-Mei / Ito, Yuko / Wang, Mei / Baumgartner, Adolf / Hayward, Simon W. / (…) / Zitzelsberger, Horst F

Reference:  technical report Jul 2009

doi: 10.2172/983010

Keywords:

Abstract: Structural chromosome aberrations are known hallmarks of many solid tumors. In the papillary form of thyroid cancer (PTC), for example, activation of the receptor tyrosine kinase (RTK) genes, ret or the neurotrophic tyrosine kinase receptor type I (NTRK1) by intra- or interchromosomal rearrangements have been suggested as a cause of the disease. The 1986 accident at the nuclear power plant in Chernobyl, USSR, led to the uncontrolled release of high levels of radioisotopes…

URL: http://www.osti.gov/bridge/product.biblio.jsp?query_id=2&page=0&osti_id=983010

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