Results of radioactive iodine treatment in children from Belarus with advanced stages of thyroid cancer after the Chernobyl accident,
Author: Reiners, Christoph / Biko, Johannes / Demidchik, Evgueni P / Demidchik, Yuri E / Drozd, Valentina M
Reference: International Congress Series, 1234, p.205-214, May 2002
doi: 10.1016/S0531-5131(01)00610-0
Keywords: Childhood thyroid cancer; Chernobyl; Radioiodine treatment
Abstract: Exposure of the thyroid to ionising radiation leads to an increased cancer risk. Whereas the average excess relative risk after external exposure amounts to approximately 8 per Gy, this relative risk is lower by a factor of 2 after exposure to radioiodine. The risk is greatest in newborns and small children below age of 5, intermediate in adolescents and questionable in adults. Papillary thyroid cancer with a relative incidence of approximately 80% per se is typical for thyroid cancer in childhood and adolescence; however, after exposure to radioiodine, this relative frequency is increased close to 100%. Bilateral involvement, multicentric growth and cancer not limited to the thyroid gland seem to be characteristic for radiation-induced thyroid cancer. Up to now, approximately 1500 cases of thyroid cancer in children below age of 15 have been diagnosed between 1990 and 2000 after the Chernobyl accident in Belarus, the Ukraine and Russia….
URL: http://www.sciencedirect.com/science/article/pii/S0531513101006100
コメント