Author: T.K. Loganovska, S.Yu. Nechaev
Reference: Медичний всесвіт (Medical Journal), 2004
・For details of the article contact the publisher of the journal. Homepage of the publisher http://www.med-tech.com.ua/index.php?mod=perord&id=6
Author: K.N. Loganovsky
Reference: Український медичний часопис (Ukrainian Medical Magazine), 2009
Keywords: ionizing radiation, low doses, Chernobyl accident, brain, radiosensitivity, radiocerebral effects, exposure in utero.
Abstract: The aim is to analyze the current evidences on radiocerebral effects following exposure to 20 mSv on fetus and >300 mSv on thyroid in utero; 16–25 weeks — >10 mSv and >200 mSv, respectively. A life span study should be done for the cohort of prenatally irradiated persons as a result of the Chernobyl accident,as well as those exposed at the age of 0–1 years. These survivors are under increased risk of different neuropsychiatric disorders, including schizophrenia. Radiation exposure in childhood is obviously associated with dose-related cognitive decline in adulthood and neuropsychiatric disorders, including schizophrenia, later in life. The possible dose thresholds of delayed radiation brain damage are the doses as low as 0.1–1.3 Gy on the brain in childhood. In adults, the radiation-associated cerebrovascular effects were obtained at >0.15–0.25 Sv. Dose-related neuropsychiatric, neurophysiological, neuropsychological, and neuroimaging abnormalities following exposure to >0.3 Sv, neurophysiological and neuroimaging radiation markers at doses >1 Sv were revealed. Postradiation brain damage is predominantly localized in the frontal-temporal areas of the left hemisphere and involves both white and gray matter of the brain. The cerebral structural and functional abnormalities after irradiation are characteristic as frontal and temporal cortex atrophy, changes of subcortical structures and neuronal pathways, mainly in the dominant hemisphere. Adulthood radiation exposure is the risk factor for the Chronic Fatigue Syndrome as the predisposition for neurodegeneration, cognitive deficit and other neuropsychiatric disorders development, accelerating CNS ageing, as well as the new model of schizophrenia. Studies on radiation neuropsychiatric effects should be realized.
URL: http://www.umj.com.ua/wp-content/uploads/archive/71/pdf/1440_rus.pdf?upload
Author: Igumnov, S / Drozdovitch, V
Reference: European Psychiatry, 15 (4), p.244-253, Jun 2000
doi: 10.1016/S0924-9338(00)00237-6
Keywords: education; emotional disorder; exposure; prenatal; social factors; specific learning ; thyroid dose
Abstract: The study examined psychological development in 250 children at the age of 6–7 and 10–12 years who had been exposed in the prenatal period at the time of the Chernobyl accident in 1986. These children were compared to a control group of 250 children of the same age from non- and slightly contaminated areas of Belarus. The examination included psychiatric examination and intellectual assessment as well as the estimation of thyroid exposure in utero. The mean value of thyroid doses from 131I 0.39 Gy was estimated for the prenatal exposed children….
URL: http://www.sciencedirect.com/science/article/pii/S0924933800002376
Author: Igumnov, S / Drozdovitch, V
Reference: European Psychiatry, 15 (4), p.244-253, Jun 2000
doi: 10.1016/S0924-9338(00)00237-6
Keywords: education; emotional disorder; exposure; prenatal; social factors; specific learning disabilities; thyroid dose
Abstract: The study examined psychological development in 250 children at the age of 6–7 and 10–12 years who had been exposed in the prenatal period at the time of the Chernobyl accident in 1986. These children were compared to a control group of 250 children of the same age from non- and slightly contaminated areas of Belarus. The examination included psychiatric examination and intellectual assessment as well as the estimation of thyroid exposure in utero. The mean value of thyroid doses from 131I 0.39 Gy was estimated for the prenatal exposed children….
URL: http://www.sciencedirect.com/science/article/pii/S0924933800002376