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タグ「remote period after the accident」

Neurological and psychopathological syndromes as remote period effects of ionizing radiatio

Author: K.N. Loganovsky

Reference: Журн. невропатол. и психиатр. им. С.С. Корсакова. (journal of neuropathology and psychiatry named after S.S. Korsakov), 2000

Keywords:

Abstract: Neurological, psychiatric and psycho-physiological (computer EEG) surveys were conducted on 100 victims of the Chernobyl disaster, in whom acute radiation syndrome (ARS) was diagnosed in 1986, 100 employees of the Chernobyl exclusion zone, who volunteered to work in the area from 1986-1987 for 5 years or more, as well as group of comparisons (control group) with 20 healthy individuals, 50 veterans of the war in Afghanistan with effects of post-traumatic stress disorder (PTSD) and 50 veterans with effects of PTSD and mild closed head injury. In remote period of exposure, left hemisphere cortico-limbic and diencephalic-right-brain syndromes were detected. Schizophrenia and other pathologies are observed.

URL: http://nature.web.ru/db/msg.html?mid=1174807&uri=index.html

Whether low doses of ionizing radiation affect the human brain?

Author: K.N. Loganovsky

Reference: Український медичний часопис (Ukrainian Medical Magazine), 2009

Keywords: ionizing radiation, low doses, Chernobyl accident, brain, radiosensitivity, radiocerebral effects, exposure in utero.

Abstract: The aim is to analyze the current evidences on radiocerebral effects following exposure to 20 mSv on fetus and >300 mSv on thyroid in utero; 16–25 weeks — >10 mSv and >200 mSv, respectively. A life span study should be done for the cohort of prenatally irradiated persons as a result of the Chernobyl accident,as well as those exposed at the age of 0–1 years. These survivors are under increased risk of different neuropsychiatric disorders, including schizophrenia. Radiation exposure in childhood is obviously associated with dose-related cognitive decline in adulthood and neuropsychiatric disorders, including schizophrenia, later in life. The possible dose thresholds of delayed radiation brain damage are the doses as low as 0.1–1.3 Gy on the brain in childhood. In adults, the radiation-associated cerebrovascular effects were obtained at >0.15–0.25 Sv. Dose-related neuropsychiatric, neurophysiological, neuropsychological, and neuroimaging abnormalities following exposure to >0.3 Sv, neurophysiological and neuroimaging radiation markers at doses >1 Sv were revealed. Postradiation brain damage is predominantly localized in the frontal-temporal areas of the left hemisphere and involves both white and gray matter of the brain. The cerebral structural and functional abnormalities after irradiation are characteristic as frontal and temporal cortex atrophy, changes of subcortical structures and neuronal pathways, mainly in the dominant hemisphere. Adulthood radiation exposure is the risk factor for the Chronic Fatigue Syndrome as the predisposition for neurodegeneration, cognitive deficit and other neuropsychiatric disorders development, accelerating CNS ageing, as well as the new model of schizophrenia. Studies on radiation neuropsychiatric effects should be realized.

URL: http://www.umj.com.ua/wp-content/uploads/archive/71/pdf/1440_rus.pdf?upload

Chronic cerebrovascular pathology in the chernobyl accident consequences liquidators, in remote period after radiation exposure

Author: N.V. Denisyuk

Reference: Український медичний часопис (Ukrainian Medical Magazine), 2006

Keywords: ionizing radiation, Chernobyl accident, ultrasonic Dopplerography, cerebrovascular pathology

Abstract: Clinical-angioneurological peculiarities of chronic cerebrovascular pathology in remote period after radiation exposure to doses ranged from 0.025 to 3.5 Sv were determined on the basis of comprehensive clinical and neurophysiological investigations, as well as qualitative and quantitative estimation of the ultrasonic Dopplerography parameters in 100 men exposed to ionizing radiation as a result of the Chernobyl accident (liquidators; main group), 135 patients with cerebrovascular pathology (comparison group) and 63 healthy men (control group). A target artery (left internal carotid artery/ICA) and the dopplerographic marker of the radiation brain injury in dose range 0.3–3.5 Sv (reduction of the systolic circulation in the left ACI) were revealed. Disturbances of the cerebral hemodynamics in remote period after radiation exposure are etiologically heterogenous; along with general risk factors (age, alcohol abuse, tobacco smoking, somatic pathology) a role of radiation factor was determined at doses exceeded 0.3 Sv. A dose–effect relationship was revealed towards the reduction of the systolic circulation in the left ICA in liquidators irradiated by 0.3–3.5 Sv and without bad habits and liver pathology.

URL:http://www.umj.com.ua/article/445/xronicheskaya-cerebrovaskulyarnaya-patologiya-u-uchastnikov-likvidacii-posledstvij-avarii-na-chernobylskoj-aes-v-otdalennyj-period-posle-oblucheniya

VERIFICATION OF ORGANIC BRAIN DAMAGE IN REMOTE PERIOD OF ACUTE RADIATION SICKNESS

Author: Loganovsky K N, Kovalenko A N, Yuryev K L, Bomko Maria A, Antipchuk Ekaterina Yu, Denisyuk N V, Zdorenko Leonid L, Rossokha A P, Chorny A I, Dubrovina G V

Reference: Український медичний часопис (Ukrainian Medical Magazine), 2003

Keywords: organic brain damage, clinical neuropsychiatric, neuropsychological, neurophysiological, and neuroimaging surveys

Abstract: The problem of verification of organic brain damage in remote period of acute radiation sickness (ARS) is of a great significance due to the radiovulnerability of the brain is still at issue. The goal of the study was to verify the organic brain damage in remote period of ARS by clinical neuropsychiatric, neuropsychological, neurophysiological, and neuroimaging surveys of cerebral structural and functional abnormalities. The endophormous (apathetic) postradiation brain organic syndrome (encephalopathy) is compressed by microfocal neurological signs, personality disorders, negative psychopathological symptoms, depression and cognitive deficit. The structural and functional brain damage involving the frontal lobes and the left temporal lobe together with their cortico-subcortical connections and deep brain structures were revealed by neuropsychological investigation. There were dominating EEG-patterns as follows: the disorganized with predominance of a- and big spectral power of slow activity EEG-pattern and low-voltage polymorphous EEG-pattern with predominance of d- and b-power. Atherosclerotic changes, hypertensive vessel tonus, interhemispheric asymmetry of blood supply (decreased in the left hemisphere), as well as high frequency of stenos were the causes of cerebral haemodynamics disorders. Brain structural pathology revealed by magnetic-resonance imaging, predominantly, brain atrophy, enlargement of ventricula, and lacunar brain abnormalities, supported the cerebro-organic nature of the disorders. Thus, the organic brain damage in remote period of ARS has been verified by clinical neuropsychiatric.

URL: http://www.umj.com.ua/article/1029/verifikaciya-organichnogo-urazhennya-golovnogo-mozku-u-viddalenij-period-gostroi-promenevoi-xvorobi

Structural-functional characteristics of organic brain disorder of the Liquidators of the Chernobyl accident, in the remote period after exposure

Author: M.O. Bomko

Reference: dissert.cand.med.sci., Kiev, 2005

Keywords: remote period, organic brain damage, MR, ARS

Abstract: The current work is in the frame of the government’s complex project for the liquidation of the aftermaths of Chernobyl and social protection of people, in the field of neurology. Purpose of the study: To identify structural and functional cerebral bases in remote period of exposure in the dose range 0,05-4,7 Sv and to verify organic brain damage in the Chernobyl liquidators.

For the first time a quantitative analysis of MR images in the Chernobyl liquidators, including persons who have been diagnosed with ARS, with organic brain damage in remote period exposure in the dose range 0,05-4,7 Sv, is conducted.

URL: http://librar.org.ua/sections_load.php?s=medicine&id=6920

Endoscopic diagnosis of gastrointestinal tract diseases among Chernobyl nuclear power plant accident liquidators in the remote period

Title: Endoscopic diagnosis of gastrointestinal tract diseases among Chernobyl nuclear power plant accident liquidators in the remote period

Author: Ivanova, Svetlana Vasilyevna

Reference: Moscow, 2005

Keywords: radiodiagnosis, radiation therapy, endoscopic diagnosis, diseases of the gastrointestinal tract, liquidators, remote period after the accident

Abstract: Research aim; to study the structure and characteristics of the gastrointestinal tract diseases among Chernobyl nuclear power plant liquidators in the late period with the subsequent development of recommendations for diagnostic procedures and dispensary observation of this contingent of patients.

URL:http://www.dissercat.com/content/endoskopicheskaya-diagnostika-zabolevanii-zheludochno-kishechnogo-trakta-u-likvidatorov-posl

The evaluation of several indicators of cattle in the remote period after the Chernobyl accident

Title: The evaluation of several indicators of cattle in the remote period after the Chernobyl accident

Author: Zarvanskaya, Svetlana Andreyevna

Reference: Moscow, 2004

Keywords: cattle, remote period after the accident, cesium-137, forage, milk

Abstract: Objective: To investigate the influence of incorporated Cs on some indicators of cows from farms of Klintsovsky Bryansk region in the remote period after the Chernobyl accident, and evaluate the effectiveness of the sorbents to reduce the transfer of Cs from forage into milk.

URL:http://www.dissercat.com/content/otsenka-nekotorykh-pokazatelei-sostoyaniya-krupnogo-rogatogo-skota-v-otdalennyi-period-posle

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