タグ「妊娠」
Title: Chernobyl fallout and outcome of pregnancy in Finland
Author: A Auvinen, M Vahteristo, H Arvela, M Suomela, T Rahola, M Hakama, and T Rytömaa
Reference: Environ Health Perspect. 2001 February; 109(2): 179–185.
Keywords: Finland, pregnancy
Abstract: Possible effects of Chernobyl fallout on outcome of pregnancy in Finland were evaluated in a nationwide follow-up study. The outcomes were the rate of live births and stillbirths, pregnancy loss, and induced abortions by municipality. Exposure was assessed based on nationwide surveys of radiation dose rate from the Chernobyl fallout, from both external and internal exposures. Using these measurements, we estimated the monthly dose rate for each of the 455 Finnish municipalities. On average, the dose rate from Chernobyl fallout reached 50 microSv per month in May 1986–a doubling of the natural background radiation. In the most heavily affected area, 4 times the normal background dose rates were recorded. Given the underlying regional differences in live birth, stillbirth, and abortion rates, we used longitudinal analysis comparing changes over time within municipalities. A temporary decline in the live birth rate had already begun before 1986, with no clear relationship to the level of fallout. A statistically significant increase in spontaneous abortions with dose of radiation was observed. No marked changes in induced abortions or stillbirths were observed. The decrease in the live birth rate is probably not a biological effect of radiation, but more likely related to public concerns of the fallout. The effect on spontaneous abortions should be interpreted with caution, because of potential bias or confounding. Further, there is little support in the epidemiologic literature on effects of very low doses of radiation on pregnancy outcome.
URL:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240640/
Title: Fear of the unknown: ionizing radiation exposure during pregnancy
Author: Reinou S. Groen, Jin Y. Bae, Kyoung J. Lim
Reference: American Journal of Obstetrics and Gynecology, Volume 206, Issue 6, June 2012, Pages 456-462
DOI: http://dx.doi.org/10.1016/j.ajog.2011.12.001
Keywords: lactation, nuclear, pregnancy, protective measures, radiation, Fukushima
Abstract: Ionizing radiation during pregnancy can negatively impact a fetus. In light of the Fukushima nuclear plant disaster in Japan, we discuss existing knowledge on the health effects of radiation and preventive measures for pregnant women. Overall, the risk of exposure to radiation is limited but severe defects can result from fetal radiation exposure >100 mGy equivalent to 10 rad (>1000 chest x-rays). While such high-level exposure rarely occurs during single medical diagnostic procedures, caution should be exercised for pregnant women. As a protective public health measure in light of a disaster, evacuation, shielding, and elimination of ingested radioactive isotopes should all be considered. Detailed radiation reports with health effects and precautionary measures should be available for a population exposed to more than background radiation.
URL: http://www.sciencedirect.com/science/article/pii/S0002937811023520
Author: LM Irgens, RT Lie, M Ulstein, T Skeie Jensen, R Skjærven, F Sivertsen, JB Reitan, F Strand, T Strand, F Egil Skjeldestad
Reference: Biomedicine & Pharmacotherapy, Volume 45, Issue 6, 1991, Pages 233-241
DOI: http://dx.doi.org/10.1016/0753-3322(91)90023-M
Keywords: Pregnancy outcome, Chernobyl, Norway
Abstract: Pregnancy outcome has been studied in terms of legal abortions, early spontaneous abortions and total number of pregnancies (in an ad hoc study covering 6 counties) as well as various perinatal health problems (on the basis of routinely recorded data for epidemiological surveillance from the Medical Birth Registry of Norway). Apparently, no effects were observed in terms of an increased occurrence of legal abortions, while spontaneous abortions increased from 2.4% of all pregnancies during the last 12 months before the accident to 3% after the accident. At the same time, the total number of pregnancies somewhat decreased. Based on monthly measurements in each municipality of external and internal (food-based) doses, dose-response associations were assessed for a number of perinatal health problems. No associations were observed.
URL: http://www.sciencedirect.com/science/article/pii/075333229190023M
タイトル：甲状腺の高分化型癌
著者：ブーンR. T., ファンC.-Y., ハンナE. Y.
典拠：北米耳鼻科クリニック、36(1)、73-90頁、2003年2月。
デジタルオブジェクト識別子：10.1016/S0030-6665(02)00127-5
キーワード：穿刺吸引生検、ステージング、病理、乳頭癌、濾胞癌、ヒュルトレ細胞癌、治療、甲状腺摘出、頸部郭清術、アジュバント治療、予後、特別な考慮事項、小児の甲状腺がん、妊娠中の甲状腺のがん
概要：…甲状腺疾患または癌の家族歴は…において重要…基本的な診断未確定の甲状腺疾患…。結節…チェルノブイリ原子力事故の余波…甲状腺質量および関連…の期間…甲状腺がん患者は通常…
URL:http://www.sciencedirect.com/science/article/pii/S0030666502001275
タイトル：分化型甲状腺癌に対する放射性ヨウ素高用量治療は女性の生殖能または子孫への遺伝的リスクの変化と関連ない
著者：バルC., クマーA., トリパチM., チャンドラセカールN., フォムH., ムラリN. R., チャンドラP., パンツG. S.
典拠：放射線腫瘍*生物学*物理学国際ジャーナル、63(2)、449-455頁、2005年10月。
デジタルオブジェクト識別子：10.1016/j.ijrobp.2005.02.043
キーワード：分化型甲状腺癌、放射性ヨウ素、妊娠、女性生殖能力、遺伝的危険率
概要：…3例において癌の形跡がない（43…甲状腺がんの診断と治療。自発的な…３例…甲状腺の残りの評価のために…切除…チェルノブイリ原子炉事故後の発がん性の影響…
URL:http://www.sciencedirect.com/science/article/pii/S0360301605004049
タイトル：妊娠中の甲状腺疾患
著者：D. A. クラエウスキ、K. D. バーマン
典拠：北アメリカ内分泌·代謝クリニック、40(4)、739-763頁、2011年12月。
デジタルオブジェクト識別子：10.1016/j.ecl.2011.08.004
キーワード：妊娠、甲状腺機能障害、母親の甲状腺機能低下症、妊娠中毒症、バセドウ病、産後甲状腺炎、産後甲状腺炎、胎児の神経発達、甲状腺がん
概要：…甲状腺がん治療のためのヨウ素131…。甲状腺における少量の摂取に注意…診断未確定の妊娠におけるパセドウ病および甲状腺がんの治療…。1週間…できる、甲状腺がんの既往歴をもつ二人の女性はレボチロキシンのさらなる増加を必要とした…
URL:http://www.sciencedirect.com/science/article/pii/S0889852911000697
