Title: New Directions in the Treatment of Thyroid Cancer
Author: You, Y. Nancy / Lakhani, Vipul / Wells, Samuel A., Jr
Reference: Journal of the American College of Surgeons, 205 (4 Supplement), p.S45-S48, Oct 2007
doi: 10.1016/j.jamcollsurg.2007.06.323
Abstract: …oncogenesis of several thyroid cancers. Gain-of-function…patients with papillary thyroid cancer (PTC) have chromosomal…form of the receptor in thyroid cells. These chromosomal…those linked with the Chernobyl accident) and in sporadic…
URL: http://www.sciencedirect.com/science/article/pii/S1072751507011775
Title: Gene rearrangements in thyroid carcinomas after irradiation during childhood: lessons from the Chernobyl reactor accident
Author: Rabes, Hartmut M
Reference: International Congress Series, 1234, p.193-200, May 2002
doi: 10.1016/S0531-5131(01)00608-2
Keywords: Papillary thyroid carcinoma; Gene rearrangement; DNA breakpoints; Irradiation; RET
Abstract: Papillary thyroid carcinomas (PTC) developed with a high incidence in children and young adults who had been exposed to radioactive fallout in contaminated regions of Belarus after the Chernobyl reactor accident. They are informative for a molecular genetic analysis of radiation-induced PTC. In contrast to spontaneous PTC, a high prevalence of gene aberrations was found with rearrangements of the receptor tyrosine kinase gene RET in the majority of cases and a few NTRK1 rearrangements. In the rearranged form of RET, the transmembrane and extracellular parts are replaced by regulatory units of other genes….
URL: http://www.sciencedirect.com/science/article/pii/S0531513101006082
Title: Post-Chernobyl thyroid carcinoma in children
Author: Leenhardt, Laurence / Aurengo, André
Reference: Best Practice & Research Clinical Endocrinology & Metabolism, 14 (4), p.667-677, Dec 2000
doi: 10.1053/beem.2000.0109
Keywords: Chernobyl; accidents, radiation; children, thyroid carcinoma; thyroid neoplasms/*genetics; carcinoma, papillary/*genetics; molecular sequence data; mutation/*genetics; gene rearrangement; Ukraine; Belarus
Abstract: The dramatic increase in childhood thyroid carcinoma observed in Belarus and Ukraine as early as 4 years after the Chernobyl nuclear accident, is well recognized as being a consequence of exposure to radioactive iodine fallout. Uncertainties persist concerning the contamination and the dosimetric data. Thyroid nodule, cervical lymph nodes or systematic ultrasound thyroid screening in exposed children led to the diagnosis….
URL: http://www.sciencedirect.com/science/article/pii/S1521690X0090109X
Title: Scientific Facts on the Chernobyl Nuclear Accident
Reference: [PDF-328K]Mar 2012
Abstract: …UN Chernobyl Forum: “Chernobyl‘s legacy: Health…greenfacts.org/en/chernobyl/ This PDF Document is the…Introduction Where is Chernobyl? [see Annex 3, p…15 patients died from thyroid cancer, and it is roughly estimated…
URL: http://www.greenfacts.org/en/chernobyl/chernobyl-greenfacts.pdf
Title: Thyroid Cancer ATA Web Brochure
Reference: [PDF-962K]Jun 2012
Abstract: …X-rays, mammograms have not been shown to cause thyroid cancer. Thyroid cancer can also be caused by radioactive iodine released…nuclear disasters such as the 1986 accident at the Chernobyl power plant in Russia or the 2011 nuclear disaster…
URL: http://www.thyroid.org/wp-content/uploads/patients/brochures/ThyroidCancer_brochure.pdf
Title: Thyroid cancer after neck irradiation during childhood
Author: Kingston, Judith
Reference: The Lancet, 365 (9476), p.1986-1987, Jun 2005
doi: 10.1016/S0140-6736(05)66675-5
Abstract: …78% of all the secondary thyroid cancers. The paediatric thyroid gland appears to be particularly…increase (30-fold) of thyroid cancer in girls under the age of…radioactive fallout after the Chernobyl nuclear-reactor explosion…
URL:http://www.sciencedirect.com/science/article/pii/S0140673605666755
Title: Thyroid Cancer . A Comprehensive Guide to Clinical Management, 515, Edited by Leonard Wartofsky, Humana Press, 2000. ISBN-No.: 0-89603-429-1
Author: Vierhapper, H
Reference: European Journal of Radiology, 35 (3), p.224, Sep 2000
doi: 10.1016/S0720-048X(00)00151-0
Abstract: …Most patients with thyroid cancer face an excellent…type of endocrine cancer remain unanswered…nuclear power plant of Chernobyl. In regard to diagnosis…of patients with thyroid nodules, the comparatively…cases of thyroid cancer. To manage this fast…
URL: http://www.sciencedirect.com/science/article/pii/S0720048X00001510
Title: Thyroid diseases among children and adolescents in Kiev region 15 years after the Chernobyl accident
Author: Nikiforova, Natalya V / Elagin, Vladimir V / Sivachenko, Tamara P / Yatsuk, Nina N / Krivyakova, Elena V / Sribnaya, Valentina D / Tkachuk, Ludmila P,
Reference: International Congress Series, 1234, p.57-65, May 2002
doi: 10.1016/S0531-5131(01)00595-7
Keywords: Thyroid diseases; Kiev; Chernobyl
Abstract: …from 1996 to 2001, and thyroid cancer was found in 124 (34…age at the time of the Chernobyl accident, sex and age…examination. Sixteen of the cancer cases (7 males and 9 females…the risk of developing thyroid diseases. Thyroid abnormalities…
URL:http://www.sciencedirect.com/science/article/pii/S0531513101005957
Title: CHERNOBYL AND CANCER EPIDEMIOLOGY
Author: Jones, RobinRussell
Reference: The Lancet, 329 (8537), p.856, Apr 1987
doi: 10.1016/S0140-6736(87)91625-4
Abstract: …the NRPB use a thyroid cancer risk estimate of 100…produce almost 2500 extra thyroid cancers against an expected…will have reduced the thyroid dose by 36%, but this…cancers, though the total cancer detriment is closer to…radiological impact of the Chernobyl reactor accident on the…
URL: http://www.sciencedirect.com/science/article/pii/S0140673687916254
Title: Prevalence of thyroid autoantibodies in children and adolescents from Belarus exposed to the Chernobyl radioactive fallout
Author: Pacini, Furio / Vorontsova, Tatiana / Molinaro, Eleonora / Kuchinskaya, Elvira / Agate, Laura / Shavrova, Elena / Astachova, Larisa / (…) / Pincheia, Aldo
Reference: The Lancet, 352 (9130), p.763-766, Sep 1998
doi: 10.1016/S0140-6736(97)11397-6
Abstract: The long-term effects of ionising radiation, including radioiodine, on thyroid function are not well known. We compared thyroid immunity and function in two groups of children from Belarus, one of whom was exposed to the radioactive fallout of Chernobyl.
URL:http://www.sciencedirect.com/science/article/pii/S0140673697113976
