Title: SP193 – Changes in thyroid cancer incidence in Scotland post-Chernobyl
Author: Fleming, Jason / Kapoor, Karan / Black, Ian Myles
Reference: Otolaryngology – Head and Neck Surgery, 141 (3 Supplement 1), p.P146-P147, Sep 2009
doi: 10.1016/j.otohns.2009.06.466
Keywords:
Abstract: …Objectives The incidence of thyroid cancer has been shown to be…of populations. The Chernobyl nuclear power plant…incidence trends of thyroid cancer in Scotland following…incidence data for thyroid cancer by sex was obtained…
URL: http://www.sciencedirect.com/science/article/pii/S0194599809009164
Title: DNA Copy Number Alterations in Radiation-induced Thyroid Cancer
Author: Zitzelsberger, H. / Unger, K.
Reference: Clinical Oncology, 23 (4), p.289-296, May 2011
doi: 10.1016/j.clon.2011.01.154
Keywords: Array CGH; CGH; Chernobyl; genomic copy number; thyroid cancer
Abstract: For many years, gene alterations of the mitogen activated protein kinase pathway have been investigated in papillary thyroid carcinomas (PTC) and the radiation-specific induction of Ret/PTC rearrangements has been discussed in the published literature. According to recent studies, these alterations are now considered as age-related changes rather than radiation-specific changes in PTC. Thus, there is a strong motivation to search for novel alterations that might represent radiation-specific markers in PTC….
URL: http://www.sciencedirect.com/science/article/pii/S0936655511001555
Title: Kinase Expression and Chromosomal Rearrangements in Papillary Thyroid Cancer Tissues: Investigations at the Molecular and Microscopic Levels
Author: Weier, Heinz-Ulrich / Kwan, Johnson / Lu, Chun-Mei / Ito, Yuko / Wang, Mei / Baumgartner, Adolf / Hayward, Simon W. / (…) / Zitzelsberger, Horst F
Reference: technical report Jul 2009
doi: 10.2172/983010
Keywords:
Abstract: Structural chromosome aberrations are known hallmarks of many solid tumors. In the papillary form of thyroid cancer (PTC), for example, activation of the receptor tyrosine kinase (RTK) genes, ret or the neurotrophic tyrosine kinase receptor type I (NTRK1) by intra- or interchromosomal rearrangements have been suggested as a cause of the disease. The 1986 accident at the nuclear power plant in Chernobyl, USSR, led to the uncontrolled release of high levels of radioisotopes…
URL: http://www.osti.gov/bridge/product.biblio.jsp?query_id=2&page=0&osti_id=983010
Title: Radiation treatment of patients with primary pediatric malignancies: risk of developing thyroid cancer as a secondary malignancy
Author: Rose, Jessica / Wertheim, Betsy C. / Guerrero, Marlon A.
Reference: The American Journal of Surgery, 204 (6), p.881-887, Dec 2012
doi: 10.1016/j.amjsurg.2012.07.030
Keywords: Thyroid cancer , Pediatric malignancies , Radiation treatment
Abstract: …during the 1986 Chernobyl nuclear power…accident developed thyroid cancer sooner than patients…years after the Chernobyl accident, the…incidence of pediatric thyroid cancer was 62 times higher…accident. The Chernobyl population also…
URL: http://www.americanjournalofsurgery.com/article/S0002-9610(12)00465-5/abstract
Title: Thyroid, Racial/Ethnic Patterns of Cancer in U.S., 1988-1992
Reference:National Cancer Institute [PDF-47K]Aug 2008
Abstract: …groups, thyroid cancer reaches its highest…association between thyroid cancer and radiation exposure…vicinity of the Chernobyl nuclear plant disaster…Goiter and other thyroid diseases, as well…Program National Cancer Institute United…
URL: http://seer.cancer.gov/publications/ethnicity/thyroid.pdf
Title: 530 Clinical aspects and surgical treatment of post-chernobyl children’s and adolescents thyroid cancer
Author: Komissarenko, I.V. / Rybakov, S.I. / Kovalenko, A.Y. / Kvachenyuk, A.N.
Reference: European Journal of Cancer, 31 (Supplement 6), p.S113, Nov 1995
doi: 10.1016/0959-8049(95)95784-4
Keywords:
Abstract: The cases of children’s and adolescent’s thyroid cancer treated in the Surgical Clinic of the Institute of Endocrinology and Metabolism during the period from 1980 to 1994 were reviewed retrospectively. 199 patients with thyroid cancer were operated on. The analysis has shown a substantial increase in thyroid cancer incidence among children in Ukraine after the Chernobyl accident (1990 to 1994) which differs by its clinical characteristics and a high level of aggression….
URL:http://www.sciencedirect.com/science/article/pii/0959804995957844
Title: Gene Expression Profiles for Radiation-induced Thyroid Cancer
Author: Maenhaut, C. / Detours, V. / Dom, G. / Handkiewicz-Junak, D. / Oczko-Wojciechowska, M. / Jarzab, B.
Reference: Clinical Oncology, 23 (4), p.282-288, May 2011
doi: 10.1016/j.clon.2011.01.509
Keywords: Cancer; Chernobyl;papillary;radiation; thyroid; transcriptome
Abstract: The question whether radiation-induced thyroid cancer differs by its molecular biology from sporadic disease still remains. Studies on tissue from patients who developed thyroid cancer after the Chernobyl accident have provided a unique opportunity to look for biological consequences of low-dose irradiation by comparing the gene expression profile of sporadic papillary thyroid cancer (PTC), whose aetiology is unknown, and PTC induced by internal radiation. So far, four transcriptomic studies comparing radiation-induced and sporadic thyroid cancer have been reported….
URL: http://www.sciencedirect.com/science/article/pii/S0936655511005413
Title: Urinary Iodine and Goiter Prevalence in Belarus: Experience of the Belarus-American Cohort Study of Thyroid Cancer and Other Thyroid Diseases Following the Chernobyl Nuclear Accident
Author: Hatch, M. / Polyanskaya, O. / McConnell, R. / Gong, Z. / Drozdovitch, V. / Rozhko, A. / Prokopovich, A. / (…) / Zablotska, L.
Reference: Annals of Epidemiology, 20 (9), p.697, Sep 2010
doi: 10.1016/j.annepidem.2010.07.021
Keywords:
Abstract: …exposure to increase risk of thyroid disease, we examined iodine…of young people exposed to Chernobyl accident fallout who were subsequently…with the Belarus-American
URL: http://www.sciencedirect.com/science/article/pii/S1047279710001857
Title: Pathology of thyroid cancer in children and adolescents of Ukraine having been exposed as a result of the Chernobyl accident
Author: Bogdanova, Tetyana / Zurnadzhy, Lyudmila / Tronko, Mykola / Namba, Hiroyuki / Yamashita, Shunichi / Thomas, Geraldine
Reference: International Congress Series, 1299, p.256-262, Feb 2007
doi: 10.1016/j.ics.2006.09.013
Keywords: Thyroid carcinoma; Pathology; Molecular-biology; Latency; Chernobyl accident
Abstract: Pathology analysis of thyroid carcinomas removed in children and adolescents aged from 0 to 18 years at the time of the Chernobyl accident has been conducted in three age groups at the time of surgery (children aged up to 15, adolescents aged 15 to 18, and young adults aged 19 to 36 years) for three periods of observation: 1990–1995; 1996–2001; 2002–2004. In all age groups and for all periods of follow-up, papillary thyroid carcinomas (PTC) were predominant (> 90% of cases)….
URL: http://www.sciencedirect.com/science/article/pii/S0531513106006200
Title: Ukrainian thyroid–cancer rates greatly increased since Chernobyl
Author: Mitchell, Peter
Reference: The Lancet, 354 (9172), p.51, Jul 1999
doi: 10.1016/S0140-6736(05)75320-4
Keywords:
Abstract: Thyroid cancers have…since the 1986 Chernobyl nuclear power…epidemiological study ( Cancer 1999; 86: 148…of paediatric thyroid carcinomas had…the immediate Chernobyl area, the incidence of thyroid cancer has now reached…
URL: http://www.sciencedirect.com/science/article/pii/S0140673605753204
