Title: Dynamics of thyroid cancer incidence in Russia following the Chernobyl accident
Author: V K Ivanov / A I Gorsky / A F Tsyb / M A Maksyutov / E M Rastopchin
Reference: Journal of Radiological Protection, 19 (4), p.305-318, Dec 1999
doi: 10.1088/0952-4746/19/4/302
Keywords:
Abstract: This paper presents an analysis of thyroid cancer incidence in the territories of Russia most contaminated after the Chernobyl accident. In the work, data on incidence in the Bryansk, Kaluga, Orel and Tula regions (5298 000 persons) are used. Altogether, 2599 cases of thyroid cancer are considered from 1982 to 1995. Of them, 143 cases were among the population who were children and adolescents at the time of the accident in 1986. The work uses the approach based on comparison of distributions of thyroid cancer cases by age at diagnosis and age at exposure. It has been shown that since 1991 the age structure of the incidence has changed significantly with a growing proportion of cases among children and adolescents. …
URL: http://iopscience.iop.org/0952-4746/19/4/302/
Title: Time trends of thyroid cancer incidence in Ukraine after the Chernobyl accident
Author: W F Heidenreich / T I Bogdanova / A G Biryukov / N D Tronko
Reference: Journal of Radiological Protection, 24 (3), p.283-293, Sep 2004
doi: 10.1088/0952-4746/24/3/007
Keywords:
Abstract: The rate of childhood thyroid cancer incidence observed in northern Ukraine during the period 1986–1998 is described as a function of time-since-exposure, age-at-exposure, and sex. Conclusions are drawn for the excess absolute risk per dose: after a minimal latency period of about three years it shows a linear increase with time-since-exposure for at least nine years. It is roughly constant in age-at-exposure, up to 15 years. For girls exposed very young it is about a factor 2 larger than for boys. For children exposed at age 16–18 this ratio increases to about 5. The thyroids of young children are not more sensitive to radiation dose than those of older ones in absolute risk in northern Ukraine in the currently used data set. As the background is increasing with age, a constant absolute risk gives a decreasing relative risk.
URL: http://iopscience.iop.org/0952-4746/24/3/007/
Title: THYROID CANCER AND RADON LINK? A PREVIEW OF A HOSPITAL STUDY IN COLORADO SPRINGS, CO
Author: James F. Burkhart, Perri L. Dumbacher
Reference: AARST[PDF-386K] Sep 2008
Abstract: A case-control study looking at a possible correlation between indoor radon exposure and thyroid cancer is just beginning in the Colorado Springs area. The study was prompted by an observation by one of the principal investigators of the high incidence of thyroid nodules and cancers in her practice compared to the previous location at which she worked in Florida. A study has been designed which selects the cases (people with thyroid cancer) and the controls (those without thyroid cancer) from a local endocrinologist with a very large practice (hence the name, hospital study). …
URL: http://www.aarst.org/proceedings/2007/4-BurkhartRadon_and_thyroid_talk.pdf
Title: The Chernobyl Tissue Bank—integrating international research on thyroid cancer
Author: Thomas, Geraldine A.
Reference: International Congress Series, 1258, p.21-30, Nov 2003
doi: 10.1016/S0531-5131(03)01141-5
Keywords: Chernobyl; Thyroid cancer; Tissue bank; Radiation
Abstract: The Chernobyl Tissue Bank (CTB) is a research resource for both ongoing and future studies of the health consequences of the Chernobyl accident. To date, the only cancer to have shown a verified increase is thyroid cancer. The research so far suggests that it is primarily those who were youngest at the time of the accident who show the greatest risk, and the increase is largely restricted to one particular type of cancer of the thyroid follicular cell, papillary carcinoma. …
URL: http://www.sciencedirect.com/science/article/pii/S0531513103011415
Title: Chernobyl, radiation and thyroid cancer
Author: Williams, Dillwyn
Reference: International Congress Series, 1299, p.219-224, Feb 2007
doi: 10.1016/j.ics.2006.10.020
Keywords: Chernobyl; Radiation; Thyroid cancer; Latency; Mutation; Sensitivity
Abstract: The effects of radiation on man have been largely based on atomic bomb studies, Chernobyl exposure differs in radiation type, dose rate and tissue distribution. This review analyses the way in which Chernobyl studies have altered our understanding of radiation and thyroid carcinoma. Latency for radiation-related thyroid carcinoma is not fixed at 10 years; the time of detection of the first cases depends on the size of the outbreak. Radioiodine is not of low carcinogenicity, it is an effective thyroid carcinogen for young children for explicable reasons. Clinical, morphological and molecular studies after Chernobyl show a correlation with tumour latency, with short latency tumours largely showing RET PTC3 rearrangements, a solid type of papillary carcinoma and an aggressive clinical behaviour. …
URL: http://www.sciencedirect.com/science/article/pii/S0531513106006224
Title: Twenty years’ experience with post-Chernobyl thyroid cancer
Author: Williams, Dillwyn
Reference: Best Practice & Research Clinical Endocrinology & Metabolism, 22 (6), p.1061-1073, Dec 2008
doi: 10.1016/j.beem.2008.09.020
Keywords: thyroid cancer; radiation; Chernobyl; latency; genotype–phenotype correlation
Abstract: Chernobyl, the largest ever nuclear accident, caused a huge release of radioactive isotopes, including nearly 2 × 1018 Bq of iodine-131. Four years later an increase in thyroid cancer incidence, virtually all papillary carcinomas in children, occurred in the highly exposed areas. The increase has continued, and with increasing latency the tumour molecular and morphological pathology has changed; further changes may occur in the future. Children under the age of 1 at exposure show the highest susceptibility, and carry this risk with them into adult life; 4000 cases have been attributed to the accident, but so far very few have died. The risk falls rapidly with increasing age at exposure; it is doubtful if there is any risk for adults at exposure. Other factors linked to susceptibility to thyroid carcinogenesis after Chernobyl include dose, iodine deficiency, and genetic factors. Other consequences are briefly covered.
URL: http://www.sciencedirect.com/science/article/pii/S1521690X08001176
Title: The Chernobyl Tissue Bank, an international collaboration to investigate the relationship between the exposure to radiation in childhood and thyroid cancer
Author: Thomas, Geraldine A. / Tuttle, Michael / on behalf of the Collaborative Management Committee, Scientific Project Panel and Pathology and Blood Panels of the CTB
Reference: International Congress Series, 1299, p.167-173, Feb 2007
doi: 10.1016/j.ics.2006.10.015
Keywords: Chernobyl; Tissue bank Molecular biology
Abstract: The only unequivocal radiological effect of the Chernobyl accident on human health is the increase in thyroid cancer in those exposed in childhood. In response to the scientific interest in studying the molecular biology of thyroid cancer post-Chernobyl, the Chernobyl Tissue Bank (CTB: www.chernobyltissuebank.com) was established. ･･･
URL:http://www.sciencedirect.com/science/article/pii/S0531513106005930
Title: No increase in thyroid cancer among children and adolescents in Finland due to Chernobyl accident
Author: But, Anna / Kurttio, Päivi / Heinävaara, Sirpa / Auvinen, Anssi,
Reference: European Journal of Cancer, 42 (8), p.1167-1171, May 2006
doi: 10.1016/j.ejca.2006.03.006
Keywords: Radiation effects; Thyroid neoplasms; Incidence; Chernobyl; Finland
Abstract: The aim of the study was to assess whether radioactive fallout from the Chernobyl accident in 1986 influenced thyroid cancer incidence among children and adolescents in Finland. The population was divided into two: those with thyroid doses less than 0.6 mSv and above 0.6 mSv. Cumulative incidence of thyroid cancer was identified from the Finnish Cancer Registry from a population aged 0–20 years in 1986 with a total of 1,356,801 persons. No clear difference in underlying thyroid cancer incidences rates were found during the pre-Chernobyl period (1970–1985) (rate ratio RR 0.95, 95% confidence interval CI 0.81–1.10). During the post-Chernobyl period (1991–2003), thyroid cancer incidence was lower in the more exposed population than in the less exposed population (RR 0.76, 95% CI 0.59–0.98). Our results did not indicate any increase in thyroid cancer incidence related to exposure to radiation from the Chernobyl accident.
URL: http://www.sciencedirect.com/science/article/pii/S0959804906002358
- Title: Application of the ERICA Assessment Tool to freshwater biota in Finland
Author: Vetikko, V.; Saxe´n, R.
Reference: Journal of Environmental Radioactivity, Jan. 2010, vol.101, no.1, pp. 82-7
doi: 10.1016/j.jenvrad.2009.09.001
Keywords: Aquatic plants; Assessment; Dose rate; ERICA; Fish; Freshwater biota; Radioactivity
Abstract: In recent years there has been growing international interest in the assessment of doses and risks from ionising contaminants to biota. In this study the ERICA Tool, developed within the EC 6th Framework Programme, was applied to estimate incremental dose rates to biota in freshwater ecosystems in Finland mainly resulting from exposure to the Chernobyl-derived radionuclides 137Cs, 134Cs and 90Sr. Data sets consisting of measured activity concentrations in fish, aquatic plants, lake water and sediment for three selected lakes located in a region with high 137Cs deposition were applied in the assessment. The dose rates to most species studied were clearly below the screening level of 10 μGy h−1, indicating no significant impact of the Chernobyl fallout on these species. However, the possibility of higher dose rates to certain species living on or in the bottom sediment cannot be excluded based on this assessment.
URL: http://www.sciencedirect.com/science/article/pii/S0265931X0900215X
- Title: Testing models for predicting the behaviour of radionuclides in aquatic systems
Author: Monte, Luigi; Boyer, Patrick; Brittain, John E.; Goutal, Nicole; Heling, Rudie; Kryshev, Alexander; Kryshev, Ivan; Laptev, Gennady; Luck, Marilyne; Periañez, Raul; Siclet, Françoise; Zheleznyak, Mark.
Reference: Applied Radiation & Isotopes; Nov2008, Vol. 66 Issue 11, p1736-1740, 5p
doi: 10.1016/j.apradiso.2007.09.020
Keywords: Model; Aquatic environment; Radionuclides; Model testing; Model uncertainty
Abstract: The paper describes the main results of the international EMRAS model testing exercise for radionuclide transport in watershed-river and estuarine systems. The exercises included the following scenarios: multi-point source of 3H discharge into the Loire River (France), radioactive contamination of the Dnieper–Southern Boug estuary (Ukraine), remobilisation of radionuclide contamination from the Pripyat River floodplain (Ukraine) following the Chernobyl accident, release of radionuclides into the Techa River (Russia) and behaviour of 226Ra in the Huelva estuary (Spain).
URL: http://www.sciencedirect.com/science/article/pii/S096980430800256X
