Author: Mati Rahu, Kaja Rahu, Anssi Auvinen, Mare Tekkel, Aivars Stengrevics, Timo Hakulinen, John D. Boice Jr, Peter D. Inskip
Reference: International Journal of Cancer, Volume 119, Issue 1, pages 162–168, 1 July 2006
Keywords: neoplasms; incidence; cohort; Chernobyl; Estonia; Latvia; radiation effects
Abstract: Two cohorts of Chernobyl cleanup workers from Estonia (4,786 men) and Latvia (5,546 men) were followed from 1986 to 1998 to investigate cancer incidence among persons exposed to ionizing radiation from the Chernobyl accident. Each cohort was identified from various independent sources and followed using nationwide population and mortality registries. Cancers were ascertained by linkage with nationwide cancer registries. Overall, 75 incident cancers were identified in the Estonian cohort and 80 in the Latvian cohort. The combined-cohort standardized incidence ratio (SIR) for all cancers was 1.15 (95% confidence interval (CI) = 0.98–1.34) and for leukemia, 1.53 (95% CI = 0.62–3.17; n = 7). Statistically significant excess cases of thyroid (SIR = 7.06, 95% CI = 2.84–14.55; n = 7) and brain cancer (SIR = 2.14, 95% CI = 1.07–3.83; n = 11) were found, mainly based on Latvian data. However, there was no evidence of a dose response for any of these sites, and the relationship to radiation exposure remains to be established. Excess of thyroid cancer cases observed may have been due to screening, the leukemia cases included 2 unconfirmed diagnoses, and the excess cases of brain tumors may have been a chance finding. There was an indication of increased risk associated with early entry to the Chernobyl area and late follow-up, though not statistically significant. Further follow-up of Chernobyl cleanup workers is warranted to clarify the possible health effects of radiation exposure. (full article in English available on web)
URL: http://onlinelibrary.wiley.com/doi/10.1002/ijc.21733/full
Author: Ivanov V.K.
Reference: Health Phys. — 2007. — Vol. 93, №5. — P. 470–479.
Keywords: excess relative risk, leukemia, cerebrovascular diseases
Abstract: The presented work summarizes data on estimated radiation risks among Chernobyl emergency workers of the Russian Federation. In 1991-1998, the excess relative risk (ERR) of death from malignant neoplasm was statistically significant: excess relative risk per 1 Gy (ERR/Gy)=2.11 with 95% confidence interval (CI) (1.31-2.92). In 1991-2001, the ERR estimation for incident solid cancers gives a positive, but statistically insignificant value: ERR/Gy=0.34 with 95% CI (-0.39; 1.22). In 1986-2003, radiation risk for leukemia incidence was investigated. During the first 10 y after the Chernobyl accident (1986-1996) the relative risk (RR) of leukemia (excluding chronic lymphocytic leukemia) was statistically significant: RR=2.2 with 95% CI (1.3-3.8) for emergency workers with doses>0.15 Gy in comparison with less exposed workers. In 1986-2000, a statistically significant dose response was observed for incident cerebrovascular diseases: ERR/Gy=0.39, 95% CI=(0.004; 0.77). For doses>0.15 Gy a statistically significant risk of cerebrovascular diseases as a function of mean daily dose was observed: ERR per 0.1 Gy d(-1)=2.17 with 95% CI=(0.64; 3.69). Different but overlapping cohorts of Russian emergency workers were used for these estimations. No adjustments were made for recognized risk factors for cerebrovascular diseases. All results should be considered as preliminary.
URL: http://www.ncbi.nlm.nih.gov/pubmed/18049223
Author: Y. Iwata, K. Suzuki, T. Wakuda et al.
Reference: PLoS ONE. — 2008. — Vol. 3, № 5. — P. e2283.
Keywords: subgranular zone, immunohistochemistry, NMDA, subventicular zone
Abstract: Epidemiological studies suggest that radiation exposure may be a potential risk factor for schizophrenia in adult humans. Here, we investigated whether adult irradiation in rats caused behavioral abnormalities relevant to schizophrenia.
A total dose of 15-Gy irradiation in six fractionations during 3 weeks was exposed to the forebrain including the subventricular zone (SVZ) and subgranular zone (SGZ) with male rats in the prone position. Behavioral, immunohistochemical, and neurochemical studies were performed three months after fractionated ionizing irradiation. Three months after fractionated ionizing irradiation, the total numbers of BrdU-positive cells in both the SVZ and SGZ zones of irradiated rats were significantly lower than those of control (sham-irradiated) rats. Hyperactivity after administration of the dopaminergic agonist methamphetamine, but not the N-methyl-D-aspartate (NMDA) receptor antagonist dizocilpine, was significantly enhanced in the irradiated rats although spontaneous locomotion in the irradiated rats was significantly lower than that of controls. Behavioral abnormalities including auditory sensory gating deficits, social interaction deficits, and working memory deficits were observed in the irradiated rats.
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386242/?tool=pubmed
Author: D.A. Bazyka, S.V. Volovik, K.G. Manton et al.
Reference: International Journal of Psychophysiology. — 2004. — Vol. 54, № 1–2. — P. 118–119.
Title: Photo Planet: Chernobyl
Keywords: photography
Abstract: photos of Chernobyl
URL: http://foto-planeta.com/np/457/chernobyl.html
Title: Atlas of cesium contamination of Europe after the Chernobyl accident
Reference: Luxembourg Office for Official Publications of the European Communities, 1998
Keywords: atlas, Europe, contamination
Abstract: The European committee and ministries of Belarus, Russia and Ukraine, which are responsible for the elimination of the consequences of the accident at the Chernobyl Nuclear Power Plant, conducted a joint program to study the effects of the accident. The program was carried out during the 1992-1995 years, as part of a formal agreement between the European committee and the relevant Ministries of the three countries. One of the projects was devoted to the preparation of the Atlas fallout on the entire territory of Europe radioactive products emitted by the accident at the Chernobyl nuclear power plant.
URL: http://pripyat-city.ru/books/56-atlas-zagryazneniya-evropy-ceziem.html
Risk of development of breast cancer after exposure to ionizing radiation due to the Chernobyl accident Republican scientific-practical centre of radiation medicine and human ecology, Gomel
Author: E.Ya. Sosnovskaya, O.F. Semenenko, A.A. Silina
Reference: Медицинские новости. – 2006. – №3. – С. 31-36
Keywords: breast cancer
Abstract: The aim is of the research is to explore the causes and characteristics of frequency and dynamics of incidence of malignant tumour in women’s breasts in Gomel, having received various doses of exposure due to the Chernobyl accident, living in territories contaminated by Cesium137.
URL: http://www.mednovosti.by/journal.aspx?article=488
Author: Marchenko, Tatyana
Reference: St. Petersburg, 2005
Keywords: medical-psychological rehabilitation, population, remote period, social protection
Abstract: Objective: to study and develop concepts, principles and techniques of medical and psychological rehabilitation and social protection of the population affected by the large-scale radiation accident at the Chernobyl nuclear power plant, in the remote period.
URL:http://tekhnosfera.com/mediko-psihologicheskaya-reabilitatsiya-naseleniya-postradavshego-v-krupnomasshtabnyh-radiatsionnyh-katastrofah-v-otdalen
Author: P. Gourmelon, C. Marquette, D. Agay et al.
Reference: BJR. ― 2005. ― Suppl., 27. ― P. 62–68.
Keywords: Multiple organ failure, systemic inflammatory response syndrome, ARS
Abstract: The presence of multiple organ dysfunction syndrome (MODS) in victims of the recent accidents in Nesvizh and Tokai-mura suggests that radiation-induced systemic inflammatory response syndrome (SIRS) occurs in acute radiation sickness (ARS). Multiple organ failure (MOF) refers to the gradual and sequential failure of organs occurring after a wide spectrum of insults. MOF is believed to be the consequence of the host’s response to the insult and is strongly linked to SIRS. It is believed that SIRS is mediated by endogenous regulators that are released during the acute phase reaction. The resulting interplay of cytokines may compromise homeostasis of various organ systems, resulting in MODS. In the classical description of ARS, the role of the central nervous system (CNS) has been underestimated. Today, it is recognised that the CNS is a radiosensitive organ whose degree of dysfunction can be quantified by electrophysiological, biochemical and/or behavioural parameters. Abnormalities in CNS function defined by these parameters may occur at a low dose of whole body radiation. The evolving concept of radiation-induced MODS in ARS provides a framework for evaluating injury to the CNS. Ionising radiation also induces an inflammatory response that may be specific to the CNS. This response is observed after either local irradiation of the CNS or whole body irradiation. The relationship between inflammatory responses in the CNS and the peripheral nervous system is undefined. Whether or not the CNS inflammatory response syndrome is a consequence of SIRS or is an independent syndrome remains an open question. The answer to this question may have implications regarding therapy and medical management of irradiated victims.
URL: http://www.ncbi.nlm.nih.gov/pubmed/15975874
Title: The Poems of Lyubov Sirota
Author: Lyubov Sirota
Keywords: Pripyat, poetry
Abstract: The Chernobyl tragedy took place in front of Lubov Sirota’s eyes. She experienced the pain of parting with her home town, Pripyat, friends, family … Lyubov Sirota – a poet with a unique sense of time. Reflections on the mutilated nature, human tragedies, love – these are the main themes of her poetry.
URL: http://www.stihi.ru/avtor/svityk
http://public.wsu.edu/~brians/chernobyl_poems/chernobyl_index.html
