Author: Irina Yushkina
Reference: Вестник Могилева главная городская газета16 мая, 2013 (Bulletin of the main city of Mogilev, 16 May 2013)
Keywords:
Abstract: -How did radiation affect the thyroid gland?
– How can one determine the cells that are out of control and can bring some serious problems?
— Is there a disease prevention, and what is it?
– What should a person do if he/she suspects some change?
– The problem of iodine deficiency: this is not just a problem of Belarus: it exists in other countries too, particularly in Russia. Can we talk about tolerance, indifference, apathy manifested in people living in areas, which are endemic of iodine – is this a manifestation of the disease, or merely character traits?
URL: http://www.vestnik-mogileva.info/content/stati/irina-yushkina-o-
Title: Pregnancy outcome in Norway after Chernobyl
Author: LM Irgens, RT Lie, M Ulstein, T Skeie Jensen, R Skjærven, F Sivertsen, JB Reitan, F Strand, T Strand, F Egil Skjeldestad
Reference: Biomedicine & Pharmacotherapy, Volume 45, Issue 6, 1991, Pages 233-241
DOI: http://dx.doi.org/10.1016/0753-3322(91)90023-M
Keywords: Pregnancy outcome, Chernobyl, Norway
Abstract: Pregnancy outcome has been studied in terms of legal abortions, early spontaneous abortions and total number of pregnancies (in an ad hoc study covering 6 counties) as well as various perinatal health problems (on the basis of routinely recorded data for epidemiological surveillance from the Medical Birth Registry of Norway). Apparently, no effects were observed in terms of an increased occurrence of legal abortions, while spontaneous abortions increased from 2.4% of all pregnancies during the last 12 months before the accident to 3% after the accident. At the same time, the total number of pregnancies somewhat decreased. Based on monthly measurements in each municipality of external and internal (food-based) doses, dose-response associations were assessed for a number of perinatal health problems. No associations were observed.
URL: http://www.sciencedirect.com/science/article/pii/075333229190023M
Title: Incidence of legal abortion in Sweden after the Chernobyl accident
Author: V Odlind, A Ericson
Reference: Biomedicine & Pharmacotherapy, Volume 45, Issue 6, 1991, Pages 225-228
DOI: http://dx.doi.org/10.1016/0753-3322(91)90021-K
Keywords: Chernobyl, abortion
Abstract: The number of legal abortions in Sweden increased around the time of the Chernobyl accident, particularly in the summer and autumn of 1986. Although there was no recording of reasons for legal abortions, one might have suspected this increase to be a result of fear and anxiety after the accident. However, seen over a longer time perspective, the increase in the number of abortions started before and continued far beyond the time of the accident. There was also a simultaneous and pronounced increase in the number of births during the years subsequent to the accident. Therefore, it seems unlikely that fear of the consequences of radioactive fall-out after the Chernobyl accident resulted in any substantial increase of the number of legal abortions in Sweden.
URL: http://www.sciencedirect.com/science/article/pii/075333229190021K
Title: Mini-and microsatellite mutations in children from Chernobyl accident cleanup workers
Author: Robbert J.C Slebos, Ruth E Little, David M Umbach, Yurij Antipkin, Tamara D Zadaorozhnaja, Nikola A Mendel, Courtney A Sommer, Kathleen Conway, Eloise Parrish, Sara Gulino, Jack A Taylor
Reference: Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Volume 559, Issues 1–2, 11 April 2004, Pages 143-151
DOI: http://dx.doi.org/10.1016/j.mrgentox.2004.01.003
Keywords: Minisatellite, Microsatellite, Germline mutation, Chernobyl accident
Abstract: Knowledge about possible genotoxic effects of low-dose radiation on the human germline is limited and relies primarily on extrapolations from high-dose exposures. To test whether ionizing radiation can cause paternal genetic mutations that are transmitted to offspring, we enrolled families of 88 Chernobyl cleanup workers exposed to ionizing radiation. We analyzed DNA isolated from lymphocytes for mutations via DNA blotting with the multi-locus minisatellite probes 33.6 and 33.15 and via PCR in a panel of six tetranucleotide repeats. Children conceived before and children conceived after their father’s exposure showed no statistically significant differences in mutation frequencies. We saw an increase in germline microsatellite mutations after radiation exposure that was not statistically significant. We found no dependence of mutation rate on increasing exposure. A novel finding was that the tetranucleotide marker D7S1482 demonstrated germline hypermutability. In conclusion, our results do not support an increased level of germline minisatellite mutations but suggest a modest increase in germline mutations in tetranucleotide repeats. Small sample size, however, limited statistical power.
URL: http://www.sciencedirect.com/science/article/pii/S1383571804000099
Title: The influence of the post-Chernobyl fall out on birth defects and abortion rates in Austria
Author: Martin C.H. Haeusler, Andrea Berghold, Wolfgang Schoell, Peter Hofer, Monika Schaffer
Reference: American Journal of Obstetrics and Gynecology, Volume 167, Issue 4, Part 1, October 1992, Pages 1025-1031
DOI: http://dx.doi.org/10.1016/S0002-9378(12)80032-9
Keywords: Abnormalities, congenital, abortion, epidemiology, radioactive fallout, registries, Austria
Abstract: The influence of the radioactive fallout after the Chernobyl disaster on the rate and regional distribution of birth defects and abortion rates in southern Austria was analyzed.
URL: http://www.sciencedirect.com/science/article/pii/S0002937812800329
Author: Affiliate “Belarusian branch of the Russian-Belarusian- information center on the consequences of Chernobyl catastrophe” RSRUE “” Institute of Radiology” Ministry of Emergency Situations of the Republic of Belarus
Reference: Let us revive our Native Land together!
Keywords: thyroid cancer, cardiovascular diseases, neuropsychiatric disorders
Abstract: -Ecologic consequences, medical consequences…
Maps of deposition of iodine-131 and the number of thyroid cancer cases registered in the country, suggests that almost the entire population of Belarus has undergone “iodine shock”. In all categories of the victims of the Chernobyl accident, increases in the incidence of thyroid cancer, cardiovascular diseases, neuropsychiatric disorders are detected, which, however, in the current medical concepts, are not concerned with radiation…
-Socio-economic damages…
URL: http://www.rbic.by/index.php?option=com_content&view=article&id=107&Itemid=12
Reference: UN in Belorussia
Keywords: incidence rate, Belorussian children
Abstract: The growth of thyroid cancer in Belarus children peaked in 1995 when recorded 40 cases per 1 million young people of the republic (and in the Gomel region even more – 134 cases!), while the global incidence rate was equal to one case per million children. Since 1988, to the present, growth of the total incidence of Belarusian children has become 65.4 percent. The number of healthy children in the contaminated areas decreased from 60.5 to 20.3%, and those with chronic diseases – increased from 10.6 to 23.5%…
URL: http://un.by/chernobyl/docs/chpubtx4.html
Title: EARLY DIAGNOSIS OF RADIATION-INDUCED THYROID CANCER IN CHILDREN OF BELARUS BY ULTRASOUND
Author: V.M. Drozd, E.P. Demidchik, L.N. Harabets, A.P. Lychtchik, E.D. Cherstvoy, J. Terekhova, Chr. Reiners
Reference: International journal of radiation medicine 1999, 3.4 (3.4): 29.34
doi:
Keywords: Chernobyl accident, thyroid cancer, early diagnosis, ultrasound.
Abstract: Studies of medical consequences following the Chernobyl accident have shown that there is a need to solve specific tasks in how to use ultrasound: performing mass ultrasonic screening for early recognition of pathology; following up patients for early nosologic diagnosis, and conducting differentiated diagnosis between benignand malignant pathology of the thyroid. The purpose of the study was to explore ultrasonic visualisation of thyroid carcinoma for its early diagnosis.We have studied particularities of thyroid cancer (ultrasonic pictures) in 97 patients before surgical removal (female-male ratio 1.6:1). The ultrasonic picture of thyroid carcinoma can be categorised into two forms: nodular and diffuse. The nodular variant can be divided into nodes with limited spread (which have either regular or rather regular outlines) and nodes with a vast spread (with an irregular outline). More frequently the tumour is visualised as a hypoechogenic node. However, isoechogenic character of the node might indicate either the dissemination or multifocal growth of a tumour within the thyroid gland. Isoechogenic character of visualised cervical lymph nodes is likely to indicate the presence of malignancy in the thyroid. Thyroid carcinoma is frequently followed by metastases in the area of regional lymph nodes. Location of the node next to the thyroid capsule might cause extracapsular invasion of the tumour (pT4). Signs of «node ageing» cystic degeneration and calcification are rarely visible.
URL: http://www.physiciansofchernobyl.org.ua/magazine/PDFS/3-4_1999/3_3_99_64.pdf
Title: SCREENING OF THYROID CANCER AFTER CHERNOBYL
Author: Ashizawa K, Nagataki S
Reference: International Journal of Radiation Medicine 1999, 34 (34): 2528 25
doi:
Keywords: screening,
Abstract: Since an accurate estimation of basal incidence of thyroid diseases around Chernobyl is essentially needed to discuss the relationship between radiation and thyroid diseases. Within the framework of the Chernobyl Sasakawa Project, we have screened and monitored childhood thyroid diseases. This project completed its 5-year health screening project at the end of April 1996, and a total of about 160,000 children were examined at the diagnostic centres located around Chernobyl. The results of the health screening have been separately published every year since 1992 by the respective centres on the basis of their presentation at the Chernobyl Sasakawa Medical Symposium. In 1997 the summary of the past 5 years-medical examination has been published and now all the data of screening were open.
URL: http://www.physiciansofchernobyl.org.ua/magazine/PDFS/3-4_1999/3_3_99_63.pdf
Author: Andres-Mach M., Rola R., Fike J.R.
Reference: Cell Tissue Res. ― 2008. ― Vol. 331, № 1. ― P. 251–262.
Keywords: cognitive impairments, dentate subgranular zone
Abstract: Ionizing irradiation is an effective treatment for intracranial tumors but is limited by the potential adverse effects induced in surrounding normal brain. These effects can include cognitive impairments, and whereas the pathogenesis of such injury has not yet been definitively established, it may involve injury to the neurogenic cell population that exists in the dentate subgranular zone (SGZ) of the hippocampus. Understanding the issues surrounding this topic could have a major impact in the management of specific sequelae associated with cranial irradiation. Although radiation is now becoming a useful tool in investigations into the biology of neurogenesis, the perspective of this review is directed more toward the potential relevance of studying radiation and the stem/precursor cell response.
URL: http://www.atgcchecker.com/pubmed/17786480
