Title: Microvessel density is high in clear-cell renal cell carcinomas of Ukrainian patients exposed to chronic persistent low-dose ionizing radiation after the Chernobyl accident
Author: A. M. Romanenko, A. Ruiz-Saurí, L. Morell-Quadreny, G. Valencia, A. F. Vozianov, A. Llombart-Bosch
Reference: Virchows Archiv , June 2012, Volume 460, Issue 6, pp 611-619
DOI: 10.1007/s00428-012-1243-x
Keywords : Conventional renal cell carcinoma, Ionizing radiation, Angiogenesis, Microvessel density, CD31antibody
Abstract: During the 25-year period subsequent to the Chernobyl accident, the morbidity of malignant renal tumors in Ukraine has increased from 4.7 to 10.7 per 100,000 of the total population. Recent studies of our group have shown that increases in morbidity, aggressiveness, and proliferative activity of renal cell carcinomas (RCCs), especially clear-cell renal cell carcinoma (CCRCC), in Ukrainian patients continuously inhabiting the radio-contaminated areas could be explained by specific molecular changes influenced by the so-called “chronic persistent low-dose ionizing radiation” (CPLDIR) exposure. This study aimed to examine the role of angiogenesis in CCRCC carcinogenesis associated with CPLDIR in patients living more than 20 years in cesium 137 (137Cs) contaminated areas after the Chernobyl accident in Ukraine. Paraffin-embedded specimens of 106 CCRCs were studied: Control cases were 18 tumors from Spanish patients (group 1), 25 tumors from Ukrainian patients from so-called clean areas without known radio-contamination (group 2), and 63 tumors from Ukrainian patients from radio-contaminated areas (group 3).
URL：http://link.springer.com/article/10.1007/s00428-012-1243-x
Title: Neuropsychiatric aftermath of the Chernobyl disaster: current state of evidences
Author: Loganovsky K N
Reference: Укр. мед. часопис. (Ukrainian Medical Journal) , 6 (68) – XI/XII 2008
Keywords: Chernobyl accident, neuropsychiatric effects, ionizing radiation, brain radiosensitivity, cerebral radiation markers, State Mental Health Care System
Abstract: The neuropsychiatric aftermath of the Chernobyl disaster remain the most important medical and social problem, however their causes are at issue. There is a strong necessity to develop and implement the State Mental Health Care System for the survivors of the Chernobyl accident as well as possible in the future radiation accidents and terrorist attacks with radiologic dispersive devise (RDD or «dirty bomb»). The brain is a radiosensitive organ where its vulnerability to exposure to ionizing radiation is different: radiation brain injury is mainly localized in neocortex, cortical-limbic system and the dominant hemisphere. The neurophysiological and neuroimaging radiation markers, psychophysiological markers of prenatal irradiation and postradiation cognitive deficit are revealed.
URL:http://www.umj.com.ua/article/2205/nejropsixiatrichni-naslidki-chornobilskoi-katastrofi-suchasnij-stan-dokaziv#ru
Title: Increased incidence of malignancies in Sweden after the Chernobyl accident-a promoting effect?
Author: Martin Tondel, Peter Lindgren,1 Peter Hjalmarsson,Lennart Hardell, Bodil Persson4
Reference: AMERICAN JOURNAL OF INDUSTRIAL MEDICINE 49:159–168 (2006) [PDF-140K]Mar 2011
Keywords: caesium-137; ionising radiation; nuclear power; low dose; epidemiology; environment; background radiation; cancer; GIS; cohort
Abstract: After the Chernobyl accident in 1986, as much as 5% of the released caesium-137 was deposited in Sweden due to a heavy rainfall 2 days after the event. A study of increased incidence of malignancies was initiated after the accident.
URL: http://www.ippnw.org/pdf/chernobyl-increased-incidence-malignancies-sweden.pdf
