タグ「Liquidators」
Title: Indicators of biological age and accelerated aging in liquidators of the consequences of radiation emergency
Author: E. I. Puchkova, N. V. Alishev
Reference: Advances in Gerontology , October 2011, Volume 1, Issue 4, pp 346-351
DOI: 10.1134/S2079057011040151
Keywords: biological age, accelerated aging, social-hygienic factors, functional classes of biological age, radiation accidents, medical consequences
Abstract: The biological age (BA) of the majority of liquidators of the consequences of radiation accidents in the navy and of the liquidators of the Chernobyl NPP accident exceeds the average standard and their DBA (due BA). The BA index can be a characteristic of the influence of social-hygienic factors on the health conditions in the Special Risk Subunit whose members liquidated the consequences of the radiation accidents. It was established that the radiation effect pertains to factors dramatically increasing BA and the rate of senescence in this group of people.
ＵＲＬ：http://link.springer.com/article/10.1134/S2079057011040151
Title: Analysis of Chromosome Aberrations in Human Lymphocytes after Accidental Exposure to Ionizing Radiation
Author: Galina SNIGIRYOVA and Vladimir SHEVCHENKO
Reference: Russian Scientific Center of Roentgeno-Radiology, MOH RF, N.I. Vavilov Institute of General Genetics, RAS
Keywords: chromosomes, ionizing radiation, liquidators
Abstract: Analysis of the results of cytogenetic examination and reconstruction of irradiation doses by the frequency of chromosome aberrations in the liquidators of the consequences of the Chernobyl NPP accident.
URL：http://www.rri.kyoto-u.ac.jp/NSRG/reports/kr79/kr79pdf/Snigiryova.pdf
Title: A study of the staff, working in the Chernobyl zone, and residents of Slavutych (Ukraine) to identify the effects of radiation exposure from the Chernobyl fallout
Author: Brenda J. Rogers and Laura K. Baker
Reference: Department of Biological Sciences, Texas Tech University
Keywords:
Abstract: In October 1999, a research of the following four groups was conducted: 1) the liquidators of the Chernobyl accident (which were directly involved in the work on decontamination), 2) Ukrainian scientists who conducted research in the 30-km exclusion zone, and 3) U.S. scientists who worked in the exclusion zone, and 4) residents of Slavutich (Ukraine), who weren’t affected due to their profession from the Chernobyl fallout.
ＵＲＬ：http://www.nsrl.ttu.edu/chornobyl/rus_radiation_workers.htm
Author: Cheburakov, Boris Yulievich.
Reference: Dissert. Cand. Med. Sci., St. Petersburg, 2002.
Keywords: liquidators, male
URL: http://leb.nlr.ru/edoc/160167/Состояние-системы-гипофиз-гонады-у-мужчин-ликвидаторов-последствий-аварии-на-Чернобыльской-АЭС
Title: Molecular Genetic Characterization of the Philadelphia Chromosome Detected in Reactor Personnel Highly Exposed to Radiation from the Chernobyl Accident
Author: Horst Zitzelsberger, Harald Hessel, Konstadinos Salassidis, Hans Mittermüller, Manfred Bauchinger
Reference: Cancer Genetics and Cytogenetics, Volume 104, Issue 2, 15 July 1998, Pages 86–93
DOI:http://dx.doi.org/10.1016/S0165-4608(97)00454-8
Keywords: chromosomes, liquidators
Abstract: Clonal del(22q) chromosome aberrations were coincidentally observed in highly exposed reactor personnel of the Chernobyl power plant accident in the course of retrospective biological dosimetry. These aberrant chromosomes were detected in PHA-stimulated cultures from peripheral blood after FPG staining and revealed a morphology similar to a Philadelphia chromosome. A rearrangement of the BCR gene on 22q11 could be confirmed in unstimulated peripheral blood by RFLP analysis from three of four del(22q) carrying cases. FISH analysis of the del(22q) carrying cases with BCR- and ABL-specific DNA probes additionally exhibited a BCR-ABL fusion in 5.2 to 9% of cells in unstimulated blood. Breakpoints within the BCR gene could be located either in the M-bcr or the m-bcr region and thus, a specific breakpoint region could not be detected in these four patients. Since typical clinical leukemic symptoms associated with the translocation (9;22)(q24;q11) could not be observed in these highly irradiated subjects (1.1 to 5.8 Gy), the role of this particular aberration in the development of a radiation-induced leukemia remains obscure.
ＵＲＬ：http://www.sciencedirect.com/science/article/pii/S0165460897004548
Title: Increased level of chromosomal aberrations in lymphocytes of Chernobyl liquidators 6–10 years after the accident
Author: Natalia Slozina, Elizaveta Neronova, Tatiana Kharchenko, Alexey Nikiforov
Reference: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, Volume 379, Issue 2, 6 October 1997, Pages 121–125
DOI:http://dx.doi.org/10.1016/S0027-5107(97)00113-9
Keywords: Chromosome aberration; Liquidator; Radiation; Micronucleus
Abstract: Chromosomal aberrations (CA) were used to investigate the level of cytogenetical damage in peripheral blood lymphocytes from the liquidators in a remote period (6–10 years) after the Chernobyl accident. There was a significantly higher frequency of chromosomal radiation markers (dicentrics and rings) in the peripheral lymphocytes of the liquidators than in the control subjects. No differences between these groups were demonstrated by the micronucleus (MN) test. Increased frequency of chromatid exchanges was associated with the smoking habits of the liquidators.
ＵＲＬ：http://www.sciencedirect.com/science/article/pii/S0027510797001139
Title: Cancer incidence among the participants of the liquidation of the consequences of the Chernobyl disaster
Author: Ivanov V.K., Rastopchin E.M., Gorskiy A.I., Ryvkin V.B.
Reference: Radioation and Lisk 1996 No.8
Keywords:incidence, liquidators
Abstract: The work presents data on incidence of solid malignant neoplasms among liquidators of the Chernobyl accident which have been gathered in Russian National Medical and Dosimetric Registry from 1986 to the beginning of 1996. RNMDR contains individual dosimetric data and results of annual medical check-ups of the liquidators living on the territory of Russia. The study involves male liquidators who had no oncological diseases before arrival to the 30-km zone and for whom the following information was available: confirmed dose of external irradiation, birth date, date of arrival to the 30-km zone, time spent in the 30-km zone, results of medical checkups. The number of liquidators under study was 114504 persons, which is about 68% of all liquidators registered in RNMDR. The average dose of the considered cohort is 108 mGy, the average age at the time of their first arrival to the 30-km zone is 34.3 year and the total number of person-years spent in the zone is 797781. The liquidatorsx27; cohort is briefly characterized, cancer incidence of liquidators is compared with that of the population of Russia as a whole by calculating standardized incidence ratio (SIR). SIRs with 95% confidence intervals for all solid malignant neoplasms and cancers of the digestive system were 1.23 (1.15; 1.31) and 1.11 (1.01; 1.24) respectively. Estimation of radiation risks for the same disease classes has revealed a statistically significant increase in cancer incidence with increase in external radiation dose of liquidators.
URL: http://cyberleninka.ru/article/n/onkologicheskaya-zabolevaemost-sredi-uchastnikov-likvidatsii-posledstviy-chernobylskoy-katastrofy
Title: Analysis Of The incidence and mortality with respect to malignant neoplasms of the digestive system in the Chernobyl liquidators 1986-1997
Author: Biryukov A.P., Ivanova I.N., Gorskiy A.I, Petrov A.V., Matyash V.A.
Reference: Radiation and Lisk 2001 No.12
Keywords:
Abstract: The paper provides analysis of information about incidence and mortality with respect to malignant neoplasms of the digestive system in the Chernobyl liquidators accumulated in the Russian National Medical and Dosimetric Registry (RNMDR) in the period from 1986 to the beginning of 1998. The study includes male liquidators registered in six regional centers of the RNMDR providing most reliable medical and dosimetric data on an annual basis, namely Northwest, Volgo-Vyatsky, Central-Chernozemny, Povolzhsky, North-Caucasian and Urals. The number of liquidators under study is 96026 persons, which accounts for 57% of all liquidators registered in the RNMDR. The mean dose in the study cohort is 108 mGy, the mean age at the time of entry in the zone is 34.3 years and the total accumulated number of person-years is 1011727. The incidence and mortality rates for cancers of the digestive system were compared for liquidators and the population of Russia in general through calculation of the standardized incidence ratio (SIR) and the standardized mortality ratio (SMR). The values of SIR and SMR with 95% confidence intervals (CI) for malignant neoplasms of the digestive system were estimated to be 0.88 (0.80; 0.97) and 0.72 (0.64; 0.80), respectively. For liquidators who arrived in the zone in 1986 these are 0.97 (0.85; 1.11) and 0.81 (0.70; 0.94), respectively. During the period of 1991-1997, when SIR in liquidators became stable, the values of SIR and SMR with 95% CI for malignant neoplasms of the digestive system were 1.00 (0.90; 1.10) and 0.87 (0.78; 0.98), respectively. For liquidators who arrived in the zone in 1986 these values were 1.15 (1.00; 1.33) and 1.02 (0.86; 1.19), respectively. Estimation of radiation risks for this class of diseases did not reveal any statistically significant increase in cancer incidence or mortality with increase in external radiation dose in liquidators.
URL: http://cyberleninka.ru/article/n/analiz-zabolevaemosti-i-smertnosti-ot-zlokachestvennyh-novoobrazovaniy-pischevaritelnoy-sistemy-sredi-likvidatorov-za-1986-1997-gody
Title: Value and structure of radiation dose for emergency workers as a function of the radiation emergency mitigation phase and activity
Author: Meshkov N.A.
Reference: Journal: Radiation and Risk (Bulletin of the National Radiation and Epidemiological Registry), Year: 2009 Volume: 18 Issue: 1
Keywords: Chernobyl disaster, radionuclides, volumetric activity, entering organism, liquidators, the nature of work being performed, 137Cs content in organism, Radiation doses, radiation dose structure
Abstract: There was performed a research of the radiation dose size and radiation dose structure of those who participated in the elimination of the Chernobyl disaster consequences. It was established that the levels of 90Sr, 137Cs and 239Pu received by means of inhaling by the «liquidators» worked at the Chernobyl atomic power station site in June and July of 1986 did not exceed the limits set by radiation standards-76/87 of that time. The average radiation doses of the «liquidators» in 1986, 1987 and 1988 were 186, 98 and 47 mGy, respectively. The most dangerous exposure to radiation was received by those who participated in the decontamination of the third power generating unit of the Chernobyl atomic power station in June and July of 1986, their radiation doses being from 205,0±10,0 to 242,0±5,6 mGy. The body burden structure of the «liquidators» participated in the elimination in 1986 consisted of exposure radiation dose of external gamma irradiation (86 %), external beta irradiation (10 %) and internal irradiation caused by inhaling radionuclides (4 %). It was established that body burden was influenced by the following factors: the level of air and area radioactive contamination, duration of work in the contaminated areas, the nature of work being performed and personal protective equipment efficacy.
URL:http://cyberleninka.ru/article/n/velichina-i-struktura-doz-oblucheniya-likvidatorov-v-zavisimosti-ot-etapa-likvidatsii-posledstviy-radiatsionnoy-avarii-i-vida-rabot
