タグ「mental health」

Interhemispheric asymmetry as a cerebral basis of psychopathology in remote period after radiation exposure due the Chernobyl accident

Author: Loganovsky K N, Antipchuk Ekaterina Yu, Bomko Maria A, Denisyuk N V, Loganovskaja T K, Chuprovskaya N Yu, Yuryev K L, Zdorenko Leonid L

Reference: Український медичний часопис (Ukrainian Medical Magazine), 2006

Keywords: interhemispheric brain asymmetry, psychopathology, ionizing radiation, Chernobyl accident, neurophysiology, neuropsychology, ultrasonic dopplerography, magnetic resonance imaging

Abstract: The goal of the study was to recognize the interhemispheric asymmetry effects in appearance of psychopathology in Chernobyl accident’s survivors. Psychometric, neurophysiological, neuropsychological methods were used for assessment of the persons who had been diagnosed with Acute Radiation Sickness (ARS), clean-up workers (liquidators), prenatally exposed children, and relevant comparison and control groups. Also the ultrasonic dopplerography and magnetic resonance imaging with their qualitative and quantitative estimations were done. It was revealed that the damage of the left, dominant, hemisphere is characteristic for the ARS-patients, liquidators exposed to more than 0.3 Sv and prenatally exposed children. The structural and functional features of radiation brain damage consists of the reduction of the systolic circulation in the left internal carotid artery, pathology of cerebral cortex, subcortical structures, neuronal pathways and cortical-limbic system of the dominant hemisphere. This cerebral pathology is the cause of negative psychopathological symptoms, cognitive disorders, depression, and personality changes that are typical in remote period of Chernobyl accident for the liquidators exposed to more than 0.3 Sv and prenatally exposed children.

URL: http://www.umj.com.ua/article/383/mizhpivkulna-asimetriya-yak-cerebralnij-bazis-psixopatologii-u-viddalenij-period-oprominennya-vnaslidok-chornobilskoi-katastrofi

Health Effects of the Chernobyl Accident 1986-2011

Redactor: A.M. Serdyuk, V.G. Bebeshko, D.A. Bazyka

Reference: Тернопіль: ТДМУ «Укрмедкнига» (Ternopil State Medical University), 2011

Abstract: A book redacted by some of the leading Ukrainian experts. For details please contact the Ternopil State Medical University. University’s homepage: http://www.tdmu.edu.te.ua/eng/general/index.php

Ukrainian title: Медичні наслідки Чорнобильської катастрофи 1986–2011

Mental disorder in children affected by internal exposure due to the Chernobyl accident

Author: T.K. Loganovska

Reference: diss.cand.med.sci. Науковий центр радіаційної медицини АМН України (Research Center for Radiation Medicine AMS Ukraine), 2005

Keywords: prenatal acute exposure, mental disorder

Abstract: On the basis of clinical and psychophysical studies of dosimetric accompaniment of representative sample of children, who have suffered acute fetal irradiation (born between 26 April 1986 and 26 February 1987 from pregnant women evacuated from Pripyat to Kiev after the Chernobyl disaster), with a parallel population control (Kiev 50 children), we found radio-cerebral effects. Features comprehensive clinical and psychophysiological characteristic, developed diagnostic criteria of mental disorders, as a result of prenatal exposure and established risk factors affecting intellectual development, clinical and physiological state of these children etc.

URL: http://disser.com.ua/content/229475.html

Scientific rationale of the system to protect mental health in radiation emergency events (on the experience of the Chernobyl catastrophe)

Author: K.N. Loganovsky, M.A. Bomko, S.A. Chumak

Reference: Психиатрия, психотерапия и клиническая психология (Psychiatry, psychotherapy and clinical psychology), 2012

Keywords: cerebrovascular disease, organic mental disorders, depression, neurotic stress-related and somatoform disorders, protection measures

Abstract: In the victims of the Chernobyl disaster, especially the liquidators, revealed an excess of cerebrovascular disease, organic mental disorders, depression, neurotic, stress-related and somatoform disorders and alcohol dependence. Progredient character of the flow of the disease is confirmed. We have developed models for mental health care in radiation accidents and radiological terrorist attacks, differentiated algorithms of the provision of neuropsychiatric intensive care, in the structure of medical response in such events, and block model for neuropsychiatric intensive assistance for victims of radiological emergencies.


Neurological and psychopathological syndromes as remote period effects of ionizing radiatio

Author: K.N. Loganovsky

Reference: Журн. невропатол. и психиатр. им. С.С. Корсакова. (journal of neuropathology and psychiatry named after S.S. Korsakov), 2000


Abstract: Neurological, psychiatric and psycho-physiological (computer EEG) surveys were conducted on 100 victims of the Chernobyl disaster, in whom acute radiation syndrome (ARS) was diagnosed in 1986, 100 employees of the Chernobyl exclusion zone, who volunteered to work in the area from 1986-1987 for 5 years or more, as well as group of comparisons (control group) with 20 healthy individuals, 50 veterans of the war in Afghanistan with effects of post-traumatic stress disorder (PTSD) and 50 veterans with effects of PTSD and mild closed head injury. In remote period of exposure, left hemisphere cortico-limbic and diencephalic-right-brain syndromes were detected. Schizophrenia and other pathologies are observed.

URL: http://nature.web.ru/db/msg.html?mid=1174807&uri=index.html

Whether low doses of ionizing radiation affect the human brain?

Author: K.N. Loganovsky

Reference: Український медичний часопис (Ukrainian Medical Magazine), 2009

Keywords: ionizing radiation, low doses, Chernobyl accident, brain, radiosensitivity, radiocerebral effects, exposure in utero.

Abstract: The aim is to analyze the current evidences on radiocerebral effects following exposure to 20 mSv on fetus and >300 mSv on thyroid in utero; 16–25 weeks — >10 mSv and >200 mSv, respectively. A life span study should be done for the cohort of prenatally irradiated persons as a result of the Chernobyl accident,as well as those exposed at the age of 0–1 years. These survivors are under increased risk of different neuropsychiatric disorders, including schizophrenia. Radiation exposure in childhood is obviously associated with dose-related cognitive decline in adulthood and neuropsychiatric disorders, including schizophrenia, later in life. The possible dose thresholds of delayed radiation brain damage are the doses as low as 0.1–1.3 Gy on the brain in childhood. In adults, the radiation-associated cerebrovascular effects were obtained at >0.15–0.25 Sv. Dose-related neuropsychiatric, neurophysiological, neuropsychological, and neuroimaging abnormalities following exposure to >0.3 Sv, neurophysiological and neuroimaging radiation markers at doses >1 Sv were revealed. Postradiation brain damage is predominantly localized in the frontal-temporal areas of the left hemisphere and involves both white and gray matter of the brain. The cerebral structural and functional abnormalities after irradiation are characteristic as frontal and temporal cortex atrophy, changes of subcortical structures and neuronal pathways, mainly in the dominant hemisphere. Adulthood radiation exposure is the risk factor for the Chronic Fatigue Syndrome as the predisposition for neurodegeneration, cognitive deficit and other neuropsychiatric disorders development, accelerating CNS ageing, as well as the new model of schizophrenia. Studies on radiation neuropsychiatric effects should be realized.

URL: http://www.umj.com.ua/wp-content/uploads/archive/71/pdf/1440_rus.pdf?upload

Clinico-dosimetric analysis of peculiarities of intellectual development and emotional and behavioral disorders in children with oncologic pathologies on the thyroid gland

Author: S.A. Igumnov

Reference: Український медичний часопис (Ukrainian Medical Magazine), 1998

Keywords: thyroid cancer, intellectual development, emotional and behavioral disorders in children


A 25 Year Retrospective Review of the Psychological Consequences of the Chernobyl Accident

Title: A 25 Year Retrospective Review of the Psychological Consequences of the Chernobyl Accident
Author: Bromet, E.J. / Havenaar, J.M. / Guey, L.T.

Reference: Clinical Oncology, 23 (4), p.297-305, May 2011

doi: 10.1016/j.clon.2011.01.501

Keywords: Chernobyl; cognitive; epidemiology; mental health; psychological; radiation

Abstract: …A-bomb survivors, the Chernobyl evacuees found themselves…medical community. The Chernobyl disaster encompassed…responders, the high rate of thyroid cancer in exposed children…medical community that Chernobyl was the cause of illness…

URL: http://www.sciencedirect.com/science/article/pii/S0936655511005334