タグ「Molecular biology」
Title: Pathology of thyroid cancer in children and adolescents of Ukraine having been exposed as a result of the Chernobyl accident
Author: Bogdanova, Tetyana / Zurnadzhy, Lyudmila / Tronko, Mykola / Namba, Hiroyuki / Yamashita, Shunichi / Thomas, Geraldine
Reference: International Congress Series, 1299, p.256-262, Feb 2007
doi: 10.1016/j.ics.2006.09.013
Keywords: Thyroid carcinoma; Pathology; Molecular-biology; Latency; Chernobyl accident
Abstract: Pathology analysis of thyroid carcinomas removed in children and adolescents aged from 0 to 18 years at the time of the Chernobyl accident has been conducted in three age groups at the time of surgery (children aged up to 15, adolescents aged 15 to 18, and young adults aged 19 to 36 years) for three periods of observation: 1990–1995; 1996–2001; 2002–2004. In all age groups and for all periods of follow-up, papillary thyroid carcinomas (PTC) were predominant (> 90% of cases)….
URL: http://www.sciencedirect.com/science/article/pii/S0531513106006200
Title: The Chernobyl Tissue Bank, an international collaboration to investigate the relationship between the exposure to radiation in childhood and thyroid cancer
Author: Thomas, Geraldine A. / Tuttle, Michael / on behalf of the Collaborative Management Committee, Scientific Project Panel and Pathology and Blood Panels of the CTB,
Reference: International Congress Series, 1299, p.167-173, Feb 2007
doi: 10.1016/j.ics.2006.10.015
Keywords: Chernobyl; Tissue bank; Molecular biology
Abstract: The only unequivocal radiological effect of the Chernobyl accident on human health is the increase in thyroid cancer in those exposed in childhood. In response to the scientific interest in studying the molecular biology of thyroid cancer post-Chernobyl, the Chernobyl Tissue Bank (CTB: www.chernobyltissuebank.com) was established. The project is supported by the governments of Ukraine and Russia, and financially supported (US$3 M) by the European Commission, the National Cancer Institute of the USA, the Sasakawa Memorial Health Foundation of Japan and the World Health Organization. Full informed consent is obtained from donors; each case is subject to pathological review by an international panel. Aliquots of extracted nucleic acid (RNA and DNA from tissue, DNA from blood) serum are made available to researchers worldwide. …
URL: http://www.sciencedirect.com/science/article/pii/S0531513106005930
Title: The Chernobyl Tissue Bank, an international collaboration to investigate the relationship between the exposure to radiation in childhood and thyroid cancer
Author: Thomas, Geraldine A. / Tuttle, Michael / on behalf of the Collaborative Management Committee, Scientific Project Panel and Pathology and Blood Panels of the CTB
Reference: International Congress Series, 1299, p.167-173, Feb 2007
doi: 10.1016/j.ics.2006.10.015
Keywords: Chernobyl; Tissue bank Molecular biology
Abstract: The only unequivocal radiological effect of the Chernobyl accident on human health is the increase in thyroid cancer in those exposed in childhood. In response to the scientific interest in studying the molecular biology of thyroid cancer post-Chernobyl, the Chernobyl Tissue Bank (CTB: www.chernobyltissuebank.com) was established. ･･･
URL:http://www.sciencedirect.com/science/article/pii/S0531513106005930
