Molecular pathology of thyroid cancer: diagnostic and clinical implications

Title: Molecular pathology of thyroid cancer: diagnostic and clinical implications

Author: Fagin, James A. / Mitsiades, Nicholas

Reference: Best Practice & Research Clinical Endocrinology & Metabolism, 22 (6), p.955-969, Dec 2008

doi: 10.1016/j.beem.2008.09.017

Keywords: thyroid cancer; pathogenesis; oncogene; RET; BRAF; RAS; molecular diagnostics; PTEN; PI3 kinase

Abstract: …receptor (RET/PTC) in thyroid cells that are constitutively…a very early event in thyroid cancer development. Thus…11 or RET/PTC3 12 in thyroid cells. In addition…characteristics. In post-Chernobyl pediatric cancers RET…

URL: http://www.sciencedirect.com/science/article/pii/S1521690X08001127