タグ「Tissue bank」
Title: The Chernobyl Tissue Bank A Repository for Biomaterial and Data Used in Integrative and Systems Biology Modeling the Human Response to Radiation
Author: Geraldine Thomas, Kristian Unger, Marko Krznaric, Angela Galpine, Jackie Bethel, Christopher Tomlinson, Mark Woodbridge, Sarah Butcher
Reference: Genes 2012, 3, 278-290; [PDF-203K]May 2012
doi:10.3390/genes3020278
Keywords: Chernobyl; Tissue Bank; systems biology
Abstract: The only unequivocal radiological effect of the Chernobyl accident on human health is the increase in thyroid cancer in those exposed in childhood or early adolescence. In response to the scientific interest in studying the molecular biology of thyroid cancer post Chernobyl, the Chernobyl Tissue Bank (CTB: www.chernobyltissuebank.com) was established in 1998. Thus far it is has collected biological samples from 3,861 individuals, and provided 27 research projects with 11,254 samples. The CTB was designed from its outset as a resource to promote the integration of research and clinical data to facilitate a systems biology approach to radiation related thyroid cancer. The project has therefore developed as a multidisciplinary collaboration between clinicians, dosimetrists, molecular biologists and bioinformaticians and serves as a paradigm for tissue banking in the omics era.
URL: http://www.mdpi.com/2073-4425/3/2/278/pdf
Title: PP94 The Chernobyl Tissue Bank – a model for integrating “omics” research on single blocks of tissue
Author: Thomas, G.
Reference: European Journal of Cancer Supplements, 7 (4), p.31, Oct 2009
doi: 10.1016/S1359-6349(09)72214-1
Abstract: …by fallout from the Chernobyl accident and who developed thyroid cancer. Patients give generic…each patient with cancer presented an overlapping…by fallout from the Chernobyl accident and who developed thyroid cancer. Patients give generic…
URL: http://www.sciencedirect.com/science/article/pii/S1359634909722141
Title: Chernobyl Sasakawa Health and Medical Cooperation Project
Author: Shigematsu, Itsuzo
Reference: International Congress Series, 1234, p.3-6, May 2002
doi: 10.1016/S0531-5131(01)00589-1
Keywords: Chernobyl accident; Sasakawa Project; Thyroid cancer; Tissue bank; Telemedicine
Abstract: …A telemedicine program between the Gomel Center and Nagasaki University School of Medicine, and an international cooperative project to establish thyroid cancer tissue banks are also being implemented. It is expected that all these programs have contributed to their original objectives, which were to provide support for the three Republics in their efforts to supply the best medical care for the people affected by the Chernobyl accident.
URL: http://www.sciencedirect.com/science/article/pii/S0531513101005891
Title: Ten-year Chernobyl aid programmes of the Otto Hug Strahleninstitut-MHM: treatment and research projects on thyroid cancer in Belarus
Author: Lengfelder, Edmund / Demidchik, Evgueni P. / Demidchik, Yuri E. / Sidorov, Yury D. / Gedrevich, Zigmund E. / Birukova, Ludmila W. / Gamolina, Larisa I. / (…) / Frenzel, Christine
Reference: International Congress Series, 1234, p.201-204, May 2002
doi: 10.1016/S0531-5131(01)00609-4
Keywords: Chernobyl; Thyroid cancer; Thyroid pathology; Medical care; Tissue bank
Abstract: The unexpected serious increase in the incidence of thyroid cancer following the reactor accident in Chernobyl led to considerable research efforts from abroad and the support of Belarus in order to mitigate these health problems. In 1991, the Otto Hug Strahleninstitut-MHM (Otto Hug Radiation Institute), a German non-governmental medical–scientific charity organization, started several long-term aid programmes and treatment and research projects on thyroid cancer and other diseases of this organ. Since 1993, the project “Thyroid Center Gomel” had more than 70 000 patients from this region for the diagnosis and treatment of thyroid diseases including cancer. …More than 6500 thyroid tumours were diagnosed, preparing over 30 000 pathological slides. In 1997, the project of “Radioiodine Therapy” started in Gomel, giving treatment to more than 450 patients since that time. …
URL:http://www.sciencedirect.com/science/article/pii/S0531513101006094
Title: The Chernobyl Tissue Bank, an international collaboration to investigate the relationship between the exposure to radiation in childhood and thyroid cancer
Author: Thomas, Geraldine A. / Tuttle, Michael / on behalf of the Collaborative Management Committee, Scientific Project Panel and Pathology and Blood Panels of the CTB,
Reference: International Congress Series, 1299, p.167-173, Feb 2007
doi: 10.1016/j.ics.2006.10.015
Keywords: Chernobyl; Tissue bank; Molecular biology
Abstract: The only unequivocal radiological effect of the Chernobyl accident on human health is the increase in thyroid cancer in those exposed in childhood. In response to the scientific interest in studying the molecular biology of thyroid cancer post-Chernobyl, the Chernobyl Tissue Bank (CTB: www.chernobyltissuebank.com) was established. The project is supported by the governments of Ukraine and Russia, and financially supported (US$3 M) by the European Commission, the National Cancer Institute of the USA, the Sasakawa Memorial Health Foundation of Japan and the World Health Organization. Full informed consent is obtained from donors; each case is subject to pathological review by an international panel. Aliquots of extracted nucleic acid (RNA and DNA from tissue, DNA from blood) serum are made available to researchers worldwide. …
URL: http://www.sciencedirect.com/science/article/pii/S0531513106005930
Title: The Chernobyl Tissue Bank—integrating international research on thyroid cancer
Author: Thomas, Geraldine A.
Reference: International Congress Series, 1258, p.21-30, Nov 2003
doi: 10.1016/S0531-5131(03)01141-5
Keywords: Chernobyl; Thyroid cancer; Tissue bank; Radiation
Abstract: The Chernobyl Tissue Bank (CTB) is a research resource for both ongoing and future studies of the health consequences of the Chernobyl accident. To date, the only cancer to have shown a verified increase is thyroid cancer. The research so far suggests that it is primarily those who were youngest at the time of the accident who show the greatest risk, and the increase is largely restricted to one particular type of cancer of the thyroid follicular cell, papillary carcinoma. …
URL: http://www.sciencedirect.com/science/article/pii/S0531513103011415
Title: The Chernobyl Tissue Bank, an international collaboration to investigate the relationship between the exposure to radiation in childhood and thyroid cancer
Author: Thomas, Geraldine A. / Tuttle, Michael / on behalf of the Collaborative Management Committee, Scientific Project Panel and Pathology and Blood Panels of the CTB
Reference: International Congress Series, 1299, p.167-173, Feb 2007
doi: 10.1016/j.ics.2006.10.015
Keywords: Chernobyl; Tissue bank Molecular biology
Abstract: The only unequivocal radiological effect of the Chernobyl accident on human health is the increase in thyroid cancer in those exposed in childhood. In response to the scientific interest in studying the molecular biology of thyroid cancer post-Chernobyl, the Chernobyl Tissue Bank (CTB: www.chernobyltissuebank.com) was established. ･･･
URL:http://www.sciencedirect.com/science/article/pii/S0531513106005930
