カテゴリー「thyroid cancer」
Title: Thyroid surgery: what has changed from (1970 to 2004): a Turkish perspective
Author: Karakoc, Derya / Erol, Timucin / Memmedova, Bibihanim / Memis, Alptekin / Sayek, Iskender,
Reference: The American Journal of Surgery, 198 (1), p.12-16, Jul 2009
doi: 10.1016/j.amjsurg.2008.08.027
Keywords: Thyroid surgery; Pathology; Changes
Abstract: …factor such as the Chernobyl nuclear disaster…Unfortunately, thyroid cancer has become a problem…attributed to the Chernobyl disaster. 17 Turkey…know the relation of thyroid cancer to the Chernobyl accident, but as…
URL: http://www.sciencedirect.com/science/article/pii/S0002961009000944
Title: The silver anniversary of the Chernobyl accident. Where are we now?
Author: Richard Wakeford
Reference: Journal of Radiological Protection, 31 (1), p.1-7, Mar 2011
doi: 10.1088/0952-4746/31/1/E02
Abstract: …radiation-induced thyroid cancer would appear…released from Chernobyl [10]. The…radiation-induced thyroid cancer [11], based…cancers other than thyroid cancer that might be…as a result of Chernobyl contamination…
URL: http://iopscience.iop.org/0952-4746/31/1/E02/pdf/0952-4746_31_1_E02.pdf
Title: Chernobyl – 20 years on
Author: Richard Wakeford
Reference: Journal of Radiological Protection, 26 (2), p.125-126, Jun 2006
doi: 10.1088/0952-4746/26/2/E02
Abstract: Twenty years ago on 26 April 1986, the Chernobyl nuclear reactor accident occurred (or, more precisely, the explosion that marked the start of the accident occurred – the resultant fire lasted several days). This is by far the largest unintentional release of radioactive material into the environment and caused widespread contamination in Europe, which was sufficiently great in the vicinity of Chernobyl to require evacuation of the population. Much attention has been paid to the possible effects on health of the resulting exposure to radiation, but the rapidity of the appearance and the magnitude of the excess cases of childhood thyroid cancer in the heavily contaminated areas of Belarus, Ukraine and Russia took most people by surprise. The striking excess of thyroid cancer among those exposed as children is undoubtedly attributable to the high thyroid doses received from radioiodine released during the accident…
URL: http://iopscience.iop.org/0952-4746/26/2/E02
Title: Molecular cytogenetic characterization of a human thyroid cancercell line
Author: Weier, Heinz-Ulrich G. / Tuton, Tiffany B. / Ito, Yuko / Chu, LisaW. / Lu, Chung-Mei / Baumgartner, Adolf / Zitzelsberger, Horst F. / Weier, Jingly F.
Reference: Cytogenetics and Genome Research; Journal Volume: 114; Related Information: Journal Publication Date: 2006
Keywords: Thyroid cancer, Chernobyl, radiation effects, cytogenetics, structural chromosome aberrations, fluorescence in situ hybridization, spectral karyotyping, chromosome
Abstract: The incidence of papillary thyroid carcinoma (PTC) increases significantly after exposure of the head and neck region to ionizing radiation, yet we know neither the steps involved in malignant transformation of thyroid epithelium nor the specific carcinogenic mode of action of radiation. Such increased tumor frequency became most evident in children after the 1986 nuclear accident in Chernobyl, Ukraine. …To study the etiology of radiation-induced thyroid cancer, we formed an international consortium to investigate chromosomal changes and altered gene expression in cases of post-Chernobyl chPTC. Our approach is based on karyotyping of primary cultures established from chPTC specimens, establishment of cell lines and studies of genotype-phenotype relationships through high resolution chromosome analysis, DNA/cDNA micro-array studies, and mouse xenografts that test for tumorigenicity….
URL: http://www.osti.gov/bridge/purl.cover.jsp?purl=/901816-6SPdNw/
Title: Increased incidence of malignancies in Sweden after the Chernobyl accident-a promoting effect?
Author: Martin Tondel, Peter Lindgren,1 Peter Hjalmarsson,Lennart Hardell, Bodil Persson4
Reference: AMERICAN JOURNAL OF INDUSTRIAL MEDICINE 49:159–168 (2006) [PDF-140K]Mar 2011
Keywords: caesium-137; ionising radiation; nuclear power; low dose; epidemiology; environment; background radiation; cancer; GIS; cohort
Abstract: After the Chernobyl accident in 1986, as much as 5% of the released caesium-137 was deposited in Sweden due to a heavy rainfall 2 days after the event. A study of increased incidence of malignancies was initiated after the accident.
URL: http://www.ippnw.org/pdf/chernobyl-increased-incidence-malignancies-sweden.pdf
Title: Estimation of thyroid doses and health risks resulting from the intake of radioactive iodine in foods and drinking water by the citizens of Tokyo after the Fukushima nuclear accident
Author: Murakami, Michio / Oki, Taikan
Reference: Chemosphere, 87 (11), p.1355-1360, Jun 2012
doi: 10.1016/j.chemosphere.2012.02.028
Keywords: Cancer risk; Fukushima nuclear power plant accident; Ingestion dose; Internal exposure; I-131; Radionuclides
Abstract: …carcinogen, causing thyroid cancer in particular, the…from fallout from the Chernobyl accident of 1986 had…dose-related increase in thyroid cancer ( Cardis and Hatch…Health effects of the Chernobyl accident for most individuals…
URL: http://www.sciencedirect.com/science/article/pii/S0045653512002184
Title: The Evolution of Biomarkers in Thyroid Cancer From Mass Screening to a Personalized Biosignature
Author: Raymon H. Grogan †, Elliot J. Mitmaker † and Orlo H. Clark *
Reference: Cancers 2010, 2, 885-912; doi: [PDF-255K]Jun 2011
doi: 10.3390/cancers2020885
Keywords: thyroid cancer; biomarker; biological marker; molecular marker; tumor marker; molecular pathways; epigenetics; serum based biomarkers; Genomics;proteomics
Abstract: …in papillary thyroid cancer. The RET/PTC 1 and…been found in papillary thyroid cancers after radiation…nuclear accidents, such as Chernobyl, and from exposure to…in childhood papillary thyroid cancer. A high frequency of..
URL: http://www.mdpi.com/2072-6694/2/2/885/pdf
Title: Approach to and Treatment of Differentiated Thyroid Carcinoma
Author: Pacini, Furio / Castagna, Maria Grazia
Reference: Medical Clinics of North America, 96 (2), p.369-383, Mar 2012
doi: 10.1016/j.mcna.2012.01.002
Keywords: Thyroglobulin; rhTSH; 131I whole-body scan; Radioiodine therapy
Abstract: …familial nonmedullary thyroid carcinoma (FNMTC…environmental risk factor for thyroid carcinoma is exposure…the explosion of the Chernobyl nuclear reactor in 1986…incidence of malignant thyroid tumors (80 times more…development of thyroid cancer. 32–34 Presentation…
URL: http://www.sciencedirect.com/science/article/pii/S002571251200003X
Title: Influence of the Chernobyl accident on thyroid function and non-tumor morbidity
Author: Cheban, Anatoly K
Reference: International Congress Series, 1234, p.245-252, May 2002
doi: 10.1016/S0531-5131(01)00614-8
Keywords: Chernobyl disaster; Ionizing radiation; Thyroid gland; Nonstochastic effects; Chronic thyroiditis; Hypothyroidism
Abstract: We summarized the results of studies on the post-Chernobyl thyroid function among evacuees from the estrangement zone, “liquidators” of 1986 period and people living for a long time (“self-settlers”) and working in the 30-km zone. Studies were conducted using standardized procedures including clinical examination, thyroid ultrasound examination, and assay of serum thyroid hormones and anti-thyroid antibodies content. Both of the radiation exposure modes, e.g., short-term, prolonged, combined, and the radiation dose were taken into account in the analysis of the results. The data analyzed indicated that the thyroid function has been subjected to alteration through the post-Chernobyl period and that nonstochastic radiation effects on the thyroid function, i.e., chronic thyroiditis and hypothyroidism, have been emerging though gradually.
URL: http://www.sciencedirect.com/science/article/pii/S0531513101006148
Title: Histological characterization of papillary thyroid carcinoma in children, adolescents and young adults in Russia after the Chernobyl accident
Author: Lushnikov, Eugeny F / Abrossimov, Alexandre Yu
Reference: International Congress Series, 1234, p.239-244, May 2002
doi: 10.1016/S0531-5131(01)00613-6
Keywords: Chernobyl; Thyroid carcinoma; Histology
Abstract: The purpose of the study was to analyze the histological features of post-Chernobyl papillary thyroid carcinoma (PTC) that occurred in children, adolescents and young adults living in radionuclide-contaminated territories of the Russian Federation. We reviewed the histological sections of thyroid carcinoma in 123 patients (39 males and 84 females) aged 0–16 years at the time of accident from Bryansk, Kaluga, Oriol and Tula regions of Russia….
URL:http://www.sciencedirect.com/science/article/pii/S0531513101006136
